tox final Flashcards
Insoluble Ca oxalate (ACID)
M= penetration of needle ca ox crystals CS= irritation of mouth, throat, lips
Inso Ca oxalate plants
Chinese, elephant, flamingo, fishtail, skunk, devil iv, cutleaf, arrowhead, umbrella, jack, cucoo, peace lily, calla lily, philodendrum, caladium, dumcane
sol oxalate (ACID)
M= hypoCa, precip in tissues C= kidney damage
sol ox plants
pigweed, lamb, greasewood, beet, sorrel, rubarb, halgeton, purselane
isocupressic acid (ACID)
vasoconstriction, decrease uterus blood fetal cortisol/abortion
isocupressic acid plants
ponderosa, monterey
quinone (ACID)
primary photosensitivation, skin stuff
quinone plants
st. johns wort, buckwheat
tannin (ACID)
GI, kidney (brown urine, constipation, GI monos)
tannin plants
oak tree, barbados
titerpene acid + plant (ACID)
VERVAIN (yellowsage/lantana) –liver damage and hepatic photosensitizaiotn (constipation, D+, icterus, photophobia, necrosis, sloughing)
colchicine (ALK)
antimitotic, many organs
colchicie plants
autum meadow, glory lily
Diterpene ALK
Competitive block of nicotininc receptors at muscle endplate
c- sudden death, muscle weak/stiff/stagger/bloat/recumbancy/collapse
Tx: physostigmine
Diterpene alk plant
delphinium, monkshade
ergot alkaloid
vasoconstriction, gangrene, uterine contraction
indolizine alk/swainsonine + plant
inhibit enzymes, decrease glycoproteins, neuronal degen, abnormal hoof and hair
CS: neuro, infertility, congentica defacts, heart failure, decreased immune
p= locoweed
lycorine alkaloid
emetic and purgative (bulb), VD, muscle tremors, seizures, salivation`
lyocrine alkaloid plants
narcissus, kaffir lily, spider lily, barbados lily, zephyr lily, river lily
muscarine alkaloid
shrooms- stim muscarinic recepters (CNS+)
Piperidine alkaloid
nicotinic effects ganglionic and NM + then blockade —> ataxia/incoord, birth defects
piperidine alkaloid plants
hemlock, lupines, tobacco, tree tobacco, coyte tobacco
pyridine alkaloids
nicotinic receptors at autonominc gangla and NMJ (low=depol, high=blockade) –> DUMBELLS
pyridine alkaloid plants
tobacco plant, tree tobacco, lobelia