Tox Flashcards

1
Q

Serum iron levels correlating with significant GI toxicity?

A

> 300

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2
Q

Ferrous fumarate percentage of elemental iron

A

33%

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3
Q

Ferrous sulfate percentage of elemental iron

A

20%

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4
Q

Ferrous gluconate percentage of elemental iron

A

12%

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5
Q

How much whole bowel irrigation for adults? Kids?

A

2L/hr adults; 250-500 ml/h in kids

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6
Q

Indication for deferoxamine therapy

A

Serum iron >350 mcg/dL in symptomatic patient (vomiting or shock/seizures/acidosis/ams)

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7
Q

Dosing for deferoxamine

A

5mg/kg/hr. Can increase to 15mg/kg/hr if no hypotension. Not to exceed 6g in one day

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8
Q

What value of salicylate can you stop treatment

A

Less than 20

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9
Q

Two classes of threatening snakes

A

Crotalid: (pit vipers, rattlesnakes, cotton mouth)
Elapids: ( Coral snakes, cobras)

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10
Q

Crotalid venom contains:

A

Cytolytic-May cause edema, hemorrhage, and necrosis at bite site and systemic. Watch for the following: hemolysis, thrombocytopenia, DIC, vomiting, CV and Resp failure

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11
Q

Elapid venom contains:

A

Neurotoxic venom producing neurological symptoms (Diplopia, ptosis, respiratory depression, paresthesia). These symptoms tend to be delayed.

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12
Q

Characteristics of central retinal vein occlusion

A
  • Dilated and tortuous veins
  • Retinal and macular edema
  • Diffuse Retinal Hemorrhages
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13
Q

How many rotations to detorse a testicular torsion?

A

1.5 open book

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14
Q

Drunk/Obtunded cocktail

A

Thiamine, folate, Dextrose, +/- Narcan

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15
Q

Osmolal gap equation

A

Osmolal gap = measured osmolality – 2[Na] – Glucose/18 – BUN/2.8 – EtOH/4.6

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16
Q

Disposition for hypoglycemia secondary to long acting sulfonureas?

A

Admit due to long half life of sulfonylureas, could cause hypoglycemia 7-10 hours after ingestion

17
Q

Digoxin Toxicity Treatment

A

Digibind: 10 vials in acute overdose; 4-6 vials for chronic ingestion

18
Q

How to treat hyperkalemia in the setting of digoxin toxicity?

A

Everything but Calcium

19
Q

Toxic tylenol dosing

A

140 mg/kg or 7.5g ingesting in 24 hour period

20
Q

How much NAQ to give in tylenol OD

A

PO: 140mg/kg then 70 mg/kg q4hr for 17 doses
IV: 150mg/kg IV over 1 hour, then 50 mg/kg IV over 4 hours, then 100 mg/kg over 16 hours

21
Q

What is Wernicke Korsakoff?

A

Thiamine deficiency (Vitamin B1) seen in alcoholics, malnourished patients. Check for ataxia, ophthalmoplegia