Toronto Notes - GI Flashcards
Commonly forgotten causes of vomiting
Drugs, uremia, CNS disease, pregnancy
Differential of Abdominal Distention (6 F’s)
Fat, Feces, Fetus, Flatus, Fluid, Fatal growth
Causes of acute upper abdominal pain
Consider chest sources including MI, pneumonia, dissecting aneurysm
Intermittent abdo pain precipitated by eating
Obstruction (gastric outlet, small bowel), pancreatitis, ischemic bowel
Obscure but treatable causes of Abdo pain
Porphyria, angioedema, Familial Mediterranean Fever, Vasculitis (polyarteritis nodosa)
Most common cause of constipation
inadequate fiber or fluid intake
Retroperitoneal structures (SAD PUCKER)
Suprarenal glands, Aorta/IVC, Duodenum (D2-4), Pancreas (tail is intra), Ureters, Colon, Kidneys, Esophagus, Rectum
Which part of the small intestine absorbs Vitamin B12 and bile acids?
ILEUM
Key questions in dysphagia
Difficulty starting swallowing, associated symptoms (regurg, voice change, weight loss), solids/liquids/both, intermittent/progressive, hx of heartburn, change in eating habits
Odynophagia
Pain on swallowing
Key questions to ask in GERD
Dysphagia, weight loss
Foods that aggravate GERD
ETOH, caffeine, tobacco, fried foods, chocolate, peppermint, spicy foods, citrus fruit juices
Treatment for Non-erosive reflux disease
Symptom relief only; PPI PRN
Treatment for Esophagitis
Heal inflammation by PPI indefinitely or surgical fundoplication
What % of patients with Barrett’s esophagus do not report GERD symptoms?
25%
Gastric vs. Duodenal ulcers
Gastric = ALWAY BIOPSY; Duodenal = rarely malignant
Management of Peptic Ulcer Disease
Stop NSAIDS, Acid neutralization, H. pylori eradication, Quit smoking
Relationship of smoking with PUD
risk of ulcer, complications, death from ulcer, impairs healing
Questions to ask in Acute Diarrhea (THOSE FADS WILT)
Travel, Homosexual, Outbreak, Seafood, Extra-intestinal signs of IBD, FH, Abx, Diet, Steatorrhea, Weight loss, Immunosuppressed, Laxatives, Tumor hx
Infectious causes of Inflammatory Diarrhea (CaSaDiff Coli-EhShY)
Campy, Salmonella, C diff, EHEC, E histolytica, Shigella, Yersinia
Symptoms of Salmonella typhi
Rose spot rash on chest, prodrome of high fever, bradycardia, HA, abdo pain; diarrhea is not initial presentation
Vitamin K dependent coagulation factors
2,7,9,10, protein C & S
Gluten containing products (BROW)
Barley, Rye, Oats, Wheat
Initial presentation of ulcerative colitis
Non-bloody diarrhea
Complications of Inflammatory Bowel Disease (ULCERATIVE COLITIS)
Urinary calculi, Liver, Cholelithiasis, Epithelial, Retardation of growth/sex, Arthralgia, Thrombophlebitis, Iatrogenic, Vitamin deficiencies, Eyes, Colorectal cancer, Obstruction, Leakage (perf), Iron deficiency, Toxic megacolon, Inanition (wasting), Strictures/fistula
Causes of Constipation (DOPED)
Drugs, Obstruction, Pain, Endocrine, Depression
Risk factors for mortality from bleeding peptic ulcer
co-morbid disease, hemodynamic unstable, Age > 60, transfusion required
If varices isolated to stomach, think
splenic vein thrombosis
When suspecting Lower GI Bleed, need to rule out
Upper GI Bleed
Differential for Lower GI Bleed (CHAND)
Colitis (radiation, infectious, ischemic, IBD (UC>CD)), Hemorrhoids/fissure, Angiodysplasia, Neoplastic, Diverticulitis
Melena vs. Hematochezia with regards to tumor localization
Melena = right; Hematochezia = left
Management Approach to Crohn’s
Nutrition/Symptomatic (loperamide/Tylenol) –> 5-ASA/Abx –> CS –> Immunosuppression (azathioprine, 6MP, MTX) –> Immunomodulators (TNFa) –> Experimental tx/Surgery
Meds for induced remission for Crohn’s disease
5ASA, CS, Immunosuppressive, Abx, MTX, Infliximab
Meds for maintenance of remission for Crohn’s disease
Immunosuppressive, MTX, Infliximab