TORCH infections Flashcards
What TORCH infection is most commonly transmitted via vaginal delivery rather than thru the placenta?
HSV-2
Name the microbes which may pass from mother to fetus?
- Toxoplasma gondii
- Rubella
- CMV
- HIV
- HSV-2
- Syphilis
ToRCHHeS are for PLEBS - Parvovirus B19
- Listeria
- E. coli
- group B Strep
What microbes may cause meningitis in newborn aquired from the mother?
- Listeria
- Group B strep
- E. coli
- HSV-2 -> meningoencephalitis
What organisms may cause hydrops fetalis?
- Parvovirus B19
- Syphilis
What TORCH infection may cause cataracts?
Rubella
What are the symptoms of Syphilis in the newborn? (4)
- HYdrops fetalis
- Facial abnormalitis -> notched teeth, saddle nose, short maxilla
- Saber shins
- CN VIII deafness
What is the classic triad of symptoms of Rubella in newborn?
- Cataracts
- Ear deafness
- PDA - congenital heart disease
- +/- Blueberry muffin rash
I (eye) love (heart) Ruby (rubella) Earrings
What diseases/organisms may cause a blueberry muffin rash on the newborn?
- CMV
- Toxoplasmosis
- Rubella
What are the classic triad of symptoms of Toxopalsma gondii in newborn?
- Chorioretinitis
- Hydrocephalus
- Intracranial calcifications
+/- blueberry muffin rash
What is the classic sign of HIV infection in newborn>
Chronic diarrhea
- Recurrent infections
What are the maternal manifestations of Rubella infection?
- Rash
- Lymphadenopathy
- Polyarthritis
- Polyarthralgia
Fever like symptoms w. rash
What disease can CMV mimic in the mother?
Mononucleosis
What are the symptoms of CMV in the newborn?
- Hearing loss
- Seizures
- Petechial “blueberry muffin” rash
- Chorioretinitis
- Periventricular calcifications
What are the symptoms of HSV-2 in newborn?
- Meningoencephalitis
- Herpetic (vesicular) lesions
What kind of calcifications are present in the brain in toxoplasma gondii and then with CMV infection in newborn?
- Intracranial - toxoplasma gondii
- Periventricular - CMV
