Topicals Quiz

Question 1

A major therapeutic implication of extensive first-pass metabolism is that much larger oral doses than intravenous doses are required to achieve equivalent responses. Drugs in this category include all of the following EXCEPT:

A) Opioids
B) Beta adrenergic antagonists
C) Corticosteroids
D) Amiodarone

Answer 1

C

Question 2

A few published studies show that oral estrogen increases levels of CRP, a marker of inflammation that is associated with heart disease. A few studies of topical estrogen do not show an increase in CRP. What kind of evidence is this?

A) Level 1
B) Level 2
C) Level 3
D) Level 4
E) Level 5

Answer 2

E – expert opinion with explicit critical appraisal, or based on physiology, bench research or “first principles”

Question 3

Most medications are weak bases – resulting in a highly water soluble drug, In solution, a base _____ a proton. In solution, an acid _____ a proton.

Accepts, donates

Answer 3

Accepts, donates

Question 4

In solution, propranolol hydrochloride is a:

A) Weak acid
B) Weak base
C) Neutral

Answer 4

B

Question 5

Which statement is correct?

A) Estring contains estradiol and Femring contains estrace
B) Estring and Femring have the same indications
C) Femring provides about 5x as much bioavailable estradiol as Estring
D) Estring provides about 40x as much bioavailable estradiol as Femring

Answer 5

C

Question 6

Sunscreens: UVA and UVB

A) Are filtered by clear glass
B) Are present in constant levels throughout the year
C) Can cause photoaging
D) All are correct

Answer 6

C

Question 7

Sunscreens: SPF is a measure of a sunscreen’s protection against:

A) UVB
B) UVA-2
C) UVA-1
D) All are correct

Answer 7

A

Question 8

A 28 year old woman asks about use of sunscreen for her 10 month old child. Your advice

A) Only organic sunscreens are recommended for children less than 1 year old
B) Sunscreen use is generally recommended for children older than 6 months during any sun exposure that might burn unprotected skin
C) Sunscreen that has SPF > 50 should not be used in children less than a year old

Answer 8

B

Question 9

Which statement about inorganic sunscreens such as titanium dioxide and zinc oxide is correct?

A) Protect against UVA and UVB
B) The micronized formulations are more effective
C) Inorganic agents are more likely to cause skin irritation than organic preparations

Answer 9

A