Pediatric Pharm Quiz

Question 1

When compared to adults, the body content of a newborn is:

A) Mostly fat
B) Mostly water
C) Mostly muscle
D) Mostly awake

Answer 1

B

Question 2

When compared to adults, renal elimination in newborns is:

A) Significantly reduced
B) Significantly elevated
C) The same
D) Best estimated by dividing the ideal weight of a newborn by the natural logarithm of the serum creatinine

Answer 2

A

Question 3

When compared to adults, drug metabolism via the CYP 450 enzyme system in newborns is:

A) The same
B) Significantly elevated
C) Significantly reduced
D) All of the above

Answer 3

C

Question 4

When compared to adults, the acid secretion in the stomach is:

A) Significantly reduced
B) Significantly elevated
C) The same
D) Not important because all medications are 100% absorbed in the newborn

Answer 4

A

Question 5

Phase I (complex) drug metabolism is significantly reduced in newborns and in infants up to 3-5 years of age. Commonly used drugs include:

A) Antihistamines like diphenydramine
B) Cough suppressants like dextromethorphan
C) Analgesics like acetaminophen and ibuprofen
D) Antibiotics like erythromycin
E) All of the above

Answer 5

E

Question 6

In “The Spirit Catches You” book club assignment, the clinicians were careful to follow the following principles of conservative prescribing:

A) Avoid mistakenly prescribing additional drugs for refractory problems unless you appreciate the potential for patient nonadherence
B) Avoid repeating prescriptions for drugs a patient has previously failed
C) Avoid frequent switching to new drugs without clear, compelling, evidence ased reasons
D) Work with patient desires to be conservative with medications
E) Unfortunately when their patient did not have the expected response to treatment, they were unable to take a step back and consider the above statements

Answer 6

E