Topical glucocorticoids Flashcards
1
Q
Triamcinolone acetonide/Fluocinonide/Betamethasone
A
acetonide or ester forms have better potency due to high lipophilicity
2
Q
Clobetasol propionate/Halobetasol propionate/Halcinonide
A
contain 21-chloro group
enhances topical anti-inflammatory activity as it is more lipophilic
3
Q
Fluticasone propionate/Mometasone furoate
A
high lipophilicity and high binding affinity
low solubility (contains microcrystals)