Eicosanoid drugs Flashcards
1
Q
Alprostadil
A
PGE1
relaxes smooth muscles and expands blood vessels
erectile dysfunction
2
Q
Misoprostol
A
PGE1 derivative
cytoprotective
prevents peptic ulcer
terminates early pregnancy in combination with mifepristone
3
Q
Latanoprost
A
topically active PGF 2a derivative
constrict blood vessels
treat high blood pressure inside the eye (glaucoma)
4
Q
Prostacyclin
A
PGI2
inhibitor of platelet aggregation
used to treat pulmonary arterial hypertension