Eicosanoid drugs Flashcards

1
Q

Alprostadil

A

PGE1

relaxes smooth muscles and expands blood vessels

erectile dysfunction

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2
Q

Misoprostol

A

PGE1 derivative

cytoprotective

prevents peptic ulcer

terminates early pregnancy in combination with mifepristone

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3
Q

Latanoprost

A

topically active PGF 2a derivative

constrict blood vessels

treat high blood pressure inside the eye (glaucoma)

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4
Q

Prostacyclin

A

PGI2

inhibitor of platelet aggregation

used to treat pulmonary arterial hypertension

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