Topic I/10) Forms of cutaneous tuberculosis, their diagnosis and treatment

Question 1

Exogenous infection

Answer 1

Primary inoculation tuberculosis (PIT)

Tuberculosis verrucosa cutis (TVC)

Question 2

Primary inoculation tuberculosis (PIT)

Answer 2

occurs in non-immune host
a papule appears at the inoculation site, 2-3 weeks after the wound is inflicted
The lesion eventually enlarges into a painless ulcer (tuberculous chancre) to up to 5 cm, with an overlying crust. Subcutaneous abscesses

Question 3

Tuberculosis verrucosa cutis (TVC)

Answer 3

occurs in previously exposed host
initially as a papule with a violet (erythematous) halo around. It then evolves into a hyperkeratotic, warty, firm plaque. Clefts and fissures may occur in the plaque with pus and keratinous material expressed.

Question 4

Endogenous infection

Answer 4

1. lupus vulgaris(neck or head with red-brown papules/nodules)
2. scrofuloderma
3. tuberculides
4. Metastatic tuberculous abscess („tuberculous gumma”)
5. Acute miliary tuberculosis
6. Orificial tuberculosis

Question 5

treatment of TB

Answer 5

isoniazid
streptomycin
pyrazinamide
ethambutol
rifampin