Topic E Flashcards
The brain uses exclusively _____ as an energy source. However, during starvation, it can use _____.
Glucose
Ketone bodies
Glucose can be stored as _____ in the _____ and _____ for daily use. It can also be stored as _____ in adipose tissue for long-term energy storage.
Glycogen
Liver & muscle
Fat
_____ is the conversion of non-CHO sources into glucose. Those non-CHO sources include/are ____ and _____.
Gluconeogenesis
Glycerol & amino acids
State of equilibrium of the internal environment of the body
Homeostasis
_____ are enzyme activators, many of which are vitamins. The 4 specific vitamins that act as these and are required for energy production are:
Coenzymes
Thiamin (B1), Riboflavin (B2), Niacin (B3), Pantothenic acid (B5)
_____ assist enzymes and are minerals.
Cofactors
Hormones are secretions from the ______ glands. They act as chemical messengers that trigger _____.
Endocrine glands
Enzymes
Thyroxine is a hormone that stimulates the processes of _____ and _____ in the liver in order to increase blood sugar.
Gluconeogenesis
Glycogenolysis
_____ _____ _____ is the minimum amount of ENERGY needed at rest IN FASTING. It can be affected by these 2 things:
Basal Energy Expenditure (BEE)
Extremes in environmental temps and drugs (caffeine, alcohol, nicotine)
Total Energy Expenditure (TEE) is equal to _____ + _____ + _____
BEE + EEPA (Energy Expended in Physical Activity) + TEF (Thermic Effect of Food)
The _____ is the energy needed to digest, absorb, and assimilate nutrients. It constitutes ~ __ % of TEE and is greater after consumption of the macronutrients _____ and _____ than after consumption of _____.
Thermic Effect of Food (TEF)
10%
CHO and protein
Fat (think fat is the only macronutrient not chemically digested until the small intestine)
This is MEASURED in the morning, when reclining, awake, relaxed, at normal body temp, at least 12 hours after last meal and several hours after strenuous activity
Basal metabolic rate (BMR)
The BMR is calculated based on the volume of _____ consumed. Factors that affect BMR include:
(1) Sex: women have 5-10% _____ BMRs than men.
(2) The level of activity of the endocrine glands of the ______.
(3) Body composition and surface area: the more lean (more muscle mass), the _____ the BMR.
(4) Age: the younger one is, the ______ the BMR.
Oxygen consumed Lower Thyroid Greater Greater
There is a _____ increase in BMR for each degree rise in temp.
7%
To calculate BMR, use these 4 parameters/measurements:
Age
Surface area (height and weight for BMI)
Body temperature
Sex
As we know, tyroxine increases gluconeogenesis and glycogenolysis in the liver. With more glucose manufacture, more _____ is needed for the aerobic process of glycolysis. Therefore, thyroxine also secondarily increase _____ consumption.
Oxygen
Oxygen
PBI stands for ___ ___ ___ and measures the activity of the ______ gland by measuring the level of _____ produced. When PBI is elevated, BMR is _____.
Protein-bound iodine
Thyroid
Thyroxine
Elevated (Think thyroxine is T4 – a hormone that contains iodine. When T4 is elevated, PBI will in turn be elevated, and when T4 is elevated more glucose is produced and more O2 is consumed… BMR will increase.)
_____ _____ _____ is the energy expenditure MEASURED under the conditions of a short rest and controlled intake of caffeine and alcohol. It is more frequently measured than BMR and is _____ than BMR by ~10-20%.
Resting Metabolic Rate (RMR)
Greater
Indirect calorimetry is the measurement of the amount of heat generated in an oxidation reaction by measuring the amount of intake of _____ or the release of _____ or _____ and translating these quantities into a _____ _____. The Mifflin St. Joer calculates within 10% of indirect calorimetry.
Oxygen
CO2 or Nitrogen
Heat equivalent
Following changes in _____ is the MOST practical way of measuring energy balance.
Weight
_____ _____ measures the heat produced in a respiration chamber (limited usefulness).
Direct calorimetry
The most practical type of calorimetry to use to determine which nutrients are being used for energy and in determining caloric needs. It is particularly useful for athletes and burn patients.
Indirect calorimetry
Respiratory quotients are used in _____ calorimetry and is equal to:
Indirect
Volume of CO2 expired divided by volume of O2 consumed
RQ for:
1) CHO =
2) Protein =
3) Fat =
4) Mixed intake =
1) 1.0
2) 0.82
3) 0.7
4) 0.85 (just memorize the RQ for each macronutrient and take the average of the 3)
Sucrose = ___ + ___
Glucose + fructose
Maltose = ___ + ___
Glucose + glucose
Lactose = ___ + ___
Glucose + galactose
Starch represents ~ ___ % of CHO intake
50%
The polysaccharide _____ is resistant to amylase and adds bulk.
Cellulose
_____ is a nondigestible polysacchride that has thickening quality and is found in fruits.
Pectin
_____ is animal starch and is stored in the liver and muscle.
Glycogen
_____ is the intermediate product of starch breakdown.
Dextrin
Sorbitol is a sugar alcohol derived from _____. It is converted to _____ during digestion.
Glucose
Fructose
Maltitol is derived from:
Maltose
Mannitol is derived from:
Fructose
Xylitol is derived from:
Xylose (5-C sugar)
_____ is a mixture of glucose and fructose derived from splitting sucrose into its two components.
Invert sugar
Rank the following in order of sweetness (most sweet to least sweet):
Sorbitol, mannitol, glucose, fructose, galactose, invert sugar, lactose, sucrose, maltose
1) Fructose
2) Invert sugar (mixture of glucose and fructose)
3) Sucrose (glucose + fructose)
4) Glucose
5) Sorbitol (glucose sugar alcohol)
6) Mannitol (fructose sugar alcohol)
7) Galactose
8) Maltose (glucose + glucose)
9) Lactose (glucose + galactose)
(Note that all fructose derivatives/combos are at the top of the list with the exception of mannitol. Note that all monosaccharides are sweeter than their disaccharide counterparts.)
The macronutrient _____ has the primary functions of: (1) provides energy, (2) spares protein so it can be used to tissue synthesis, (3) regulates fat metabolism by preventing ketosis
CHO
All proteins contain these 4 elements:
Carbon, Hydrogen, Oxygen, Nitrogen
_____ is an element unique to cysteine, cystine, and methionine.
Sulfur
_____ can be found in contaminated raw or undercooked eggs, poultry, and meat.
Salmonella
Which type of meat has the MOST bacteria?
Ground meat
Three safe ways to thaw food:
Refrigerator thawing
COLD water thawing
Microwave thawing
Clostridium perfringens is often found in:
Meat and gravied mixtures in large quantities
A food that is bacteria-safe has a _____ PH and is moist or dry?
Low
Dry
If CHO intake is increased, which particular B vitamin needs to be increased especially?
Thiamin
Prevention of an outbreak of _____ _____ requires special care because of its ability to grow at temps of 34-113oF (can grow in the refrigerator!)
Listeria monocytogenes
The _____ test is used to find the cause of vitamin B12 deficiency.
Schilling
Ceruloplasmin = _____ enzyme. It carries _____ (mineral) in the blood.
Ferrioxidase
Copper
Illness d/t Bacillus cereus is d/t contaminated:
Rice products and starchy foods
The atomic weight of sodium (must know for mEq equations)
23
When humans smell food, the hormone _____ is released which increases appetite.
Dopamine
In humans, serotonin _____ appetite indirectly by inhibiting _____ release.
Decreases
Dopamine
The base group of an amino acid is the _____ group. The acid group is the _____ group. With both a base and an acid group, amino acids are excellent _____.
Amino group (NH2) Carboxyl group (COOH) Buffers
What are the 9 essential amino acids?
Methionine Phenylalanine Leucine Lysine Histidine Valine Isoleucine Threonine Tryptophan
There are 2 conditionally essential amino acids during catabolic stress. What are they?
Arginine and glutamine
_____ is an amino acid that is a precursor to serotonin and niacin.
Tryptophan
Phenylalanine can be converted into this amino acid.
Tyrosine (think Patient Transport or Physical Therapy)
Methionine can be converted into this amino acid.
Cysteine (think MC)
The proportion of protein in food that can be readily broken down to be used for protein synthesis in the body is known as _____.
Biological value
A food high in biological value contains greater than or equal to ___ % protein.
75
The macronutrient _____ is used for tissue synthesis, growth, and maintenance and body process regulation. It is an insufficient source of energy because ___ must be removed first. Only ___ % of it can be converted to glucose.
Protein
Nitrogen
58%
Protein requirements:
___ g/kg body weight
___ - ___ % of total energy intake
0.8
10-15
Soy protein is equivalent in protein quality to _____ protein.
Animal
Soybeans are low in the amino acid _____.
Methionine
Legumes are low in ___, ___, and ___.
Methionine, tryptophan, and cystine
Gelatin is low in ___ and ___ and has no ___.
Methionine and lysine
Tryptophan
3 fatty acids + glycerol =
a triglyceride
Most fat in food is in the form of:
Triglycerides
_____ (type of fat) are present in cell membrane and control the passage of compounds in and out of the cell. Most are lecithin which contain the lipotropic factor _____. Lipotropic compounds help catalyze fat breakdown.
Phospholipids
Choline
Lecithin contains choline which helps prevent _____ accumulation in the liver by functioning in the transport and utilization of fatty acids and cholesterol using the enzyme _____.
Fat
LCAT (Lecithin-cholesterol acyl transferase)
A total of one double bond in a fatty acid chain means that the fat is _____ while 2 or more means that the fat is _____.
Monounsaturated
Polyunsaturated
_____ oil is the most polyunsaturated.
Safflower
There are 2 essential fatty acids. They are …
Omega-6 (linoleic acid)
Omega-3 (Linolenic acid)
Hallmark signs of an omega-__ deficiency include:
Eczema
Red, purple skin spots known as _____
Poor growth rate
6
Petechiae
(Think Six = S, S = skin)
The best source of omega-6 fatty acids is _____.
Safflower oil (Again, think Six = S = safflower oil)
Omega-___ fatty acids play a role in retinal and brain development.
3
Think linoleNic = N = braiN = retiNal
Omega-___ mainly comes from fish oils, DHA and EPA. Also, walnuts, flaxseed, and _____ oil.
3
Canola
Omega-__ fatty acids decrease TG levels but have little effect on cholesterol levels.
3
Think Three = T = TG only
In replacement of dietary CHO, omega-6 fatty acids lower ____ and raise ____. In replacement of saturated fat, they lower ____ and ____.
LDL
HDL
Total cholesterol and HDL
A mortality rate of 10 means that:
10 died out of 1,000 people
not a percentage!!!
A person consumed 10 g of protein and release 6 g of Nitrogen in the urine. Is this person in nitrogen balance or in (+) or (-) balance?
Negative
(g protein/6.25) – (g UUN + 4)
(10/6.25) – (6 +4) = a negative #
Acid-base abnormality in an uncontrolled diabetic
Metabolic acidosis (think d/t increased urination leading to increased loss of bicarb)
Fresh eggs in shell can be stored in the refrigerator for up to _____.
3 weeks
Normal saline has ___ mEq Sodium/L.
154
Clostridium perfringes has a _____ onset and is _____ (aerobic/anaerobic).
Slow
Anaerobic
Aseptic means _____.
Aseptically-packaged milk should be stored at what temp?
Sterile
Room temperature
According to Chinese beliefs, food and herbs that my be used to treat illness are group as yin which means _____ and yang which means _____.
Yin = dark and cold Yang = bright and hot
A fatty acid chain consists of _____ and _____ and _____ end groups.
Hydrocarbons
Methyl and Carboxyl
To name a fatty acid chain, one must consider these 3 things.
- Number of carbon atoms in the chain
- Number of double bonds
- Location of 1st double bond
Using omega nomenclature, the location of the 1st double bond in a fatty acid chain is counted from the _____ end. This number then is used after the omega symbol (i.e.: omega 6).
Methyl
(not from the end with the least # of carbon atoms before 1st double bond as in the other nomenclature system)
(think of omega symbol as a “w” and then turn it upside down for “m” = methyl)
The process of adding hydrogen at a double bond to unsaturated fatty acids to increase saturation and stability is known as _____.
Hydrogenation