topic 7 Flashcards
what is the difference between unintentional toxins and naturally occurring toxins?
unintentional toxins: accidental, they are not there naturally and often occur due to external processes (eg. improper use of pesticides; eg. coal burning causes accumulation of mercury in tuna which can be an issue for pregnant women).
naturally occurring toxins: occur naturally in foods, not due to any external processes (eg. coniine in hemlock, green potatoes that have solanine, poisonous mushrooms, mould, etc.)
How do unintentional toxins enter the food supply?
Due to human error/action. Aldicarb (pesticide) entered food due to improper use and mercury enters food web due to coal burning which goes into air, then reacts with bacteria in water which in turn turns into methyl mercury in fish (so higher trophic levels = + mercury).
How do naturally occurring toxins enter the food supply?
They are present there naturally so they don’t really enter per se. In some cases, they can arise from time (mould) or breakdown of proteins (histamine)
difference between celiac, silent celiac, latent celiac, non-celiac gluten sensitivity
celiac: diagnosis by positive endoscopy, positive anti-tissue transglutaminase test (ANTI-tTG)
silent celiac: no symptoms, but positive blood test and biopsy
latent celiac: positive blood tests, but normal endoscopy, watchful waiting without a gf diet
non-celiac gluten sensitivity: no positive blood test or biopsy, diet helps with certain symptoms
Classical food allergy leads to…
swelling, nausea, cramping, diarrhea, eczema, itching, vomiting, flatulence, asthma, rhinitis, anaphylaxis (collapse in circulatory system that can lead to death)
How do allergic reactions work?
Body’s immune system attacks foreign substance that presents no danger by generating antibodies (protein). The latter engulf the allergen which manifests an allergic reaction. 1st exposure leads to antibody formation, 2nd exposure leads allergen exposure reaction.
What can reverse an allergic reaction? Why do we need to go to the hospital anyways?
Epinephrine/adrenaline can reverse the allergic reaction, but epi-pen needs to be in reach. It just buys time, but reaction can reoccur, so must be monitored.
what is hypoglycemia and how is it treated?
low blood sugar, the solution is to have small meals rather than high carbohydrates meals.
T or F: hyperactivity is caused by sugar
False! not caused by sugar, but rather the situation (bday parties, playground, etc.). In fact, it has a calming effect. Eg. Sheriff put prisoners on ice cream diet to calm them down as simple carbohydrates actually have a calming effect.
Why does sugar cause sleepiness?
Most of the time a.a. absorption into brain, except for tryptophan which goes into muscle tissue. However, when we eat carbohydrates, this leads to insulin release which enhances absorption of competing a.a. into muscle tissue, leading to tryptophane absorption into the brain. Due to tryptophane being a precursor for serotonin, its absorption calms us down and might induce sleep.
What should you eat to stay awake?
To stay awake, you need to consume protein, which contains tyrosine. Tyrosine goes through a cascade (tyrosine – dopamine – norepinephrine – epinephrine) to produce epinephrine (adrenaline = fight or flight hormone!!) which will keep you alert. So it is better to eat tuna before an exam than a bunch of sugar.
what are Idiosyncratic reactions
Rare reactions whose origin is unknown
MSG causes what adverse food reaction?
Chinese restaurant syndrome or Kwok’s disease, it mimics a heart attack and can cause rare, but fatal asthma
How do bacteria cause problems
1.Bacterial infection: particular bacterium multiplies in body and overruns in body.
- Bacterial intoxication: reaction to poisons produced by bacteria.
Salmonella
A bacteria often associated with chicken, causes gastroenteritis symptoms.
Campylobacter Jejuni
A bacteria, gastroenteritis symptoms, can lead to guillain barre syndrome, similar to MS where protective layer around nerve is worn away, most ppl recover
listeria monocytogenes
bacteria founds in high protein foods (cheese and processes meats) that can grow at fridge temperatures. Can come into food due to contaminated equipment (eg.Maple leaf screw in cold cut machine led to infection.)
Staphylococci
Bacteria found in skin and nasal secretions (so sneezing is a risk of contamination), produces a toxin that is heat stable (so heating doesn’t get rid of it).