Topic 6.4: Gas Exchange Flashcards

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1
Q

Physiological respiration definition

A

O2 transport to cells within tissues, where energy production occurs

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2
Q

Stages of respiration

A

a) Ventilation
b) Gas exchange
c) Respiration

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3
Q

Definition of ventilation

A

Exchange of gases between the lungs and the atmosphere (via breathing)

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4
Q

Definition of gas exchange

A

Exchange of O2 and CO2 between the alveoli and the bloodstream (via diffusion)

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5
Q

Definition of respiration

A

Process by which ATP is produced from organic molecules

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6
Q

Structures of the respiratory system (10)

A

a) Nasal cavity
b) Pharynx
c) Larynx
d) Trachea
e) Bronchi
f) Bronchioles
g) Alveoli
h) Intercostal muscles
i) Diaphragm
j) Abdominal muscles

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7
Q

Steps of respiratory system (4)

A

a) Air passes through the nose and the pharynx to the trachea.
b) Air travels down the trachea until it divides into two bronchi.
c) Inside each lung, the bronchi divides into bronchioles.
d) Each bronchiole terminates with alveoli, where gas exchange with the bloodstream occurs.

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8
Q

Purpose of ventilation

A

Maintain concentration gradients of O2 and CO2 between air in alveoli and blood in adjacent capillaries.

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9
Q

Principles of ventilation (2)

A

a) Muscle contractions cause pressure changes by modifying the volume inside the thorax
b) Gases move via passive diffusion by creating these concentration gradients.

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10
Q

Inhaling mechanism (5)

A

a) Diaphragm and exterior intercostal contract
b) Abdominals and interior intercostal relax
c) Volume of the chest cavity increases
d) Pressure in lungs decrease below atmospheric pressure
e) Air flows into the lungs to equalize the pressure

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11
Q

Exhaling mechanism (5)

A

a) Diaphragm and exterior intercostal relax
b) Abdominals and interior intercostal contract
c) Volume of the chest cavity decreases
d) Pressure in lungs increases above atmospheric pressure
e) Air flows out of the lungs to equalize the pressure.

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12
Q

Alveoli definition

A

Clusters of small sacs found at the end of the bronchioles

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13
Q

Main features of alveoli that facilitate exchange of gases (4)

A

a) Thin wall (1 cell thick)
b) Spherical shape
c) Rich capillary network
d) Fluid layer

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14
Q

Type I pneumocytes

a) Shape
b) Function

A

a) Extremely thin

b) Makes up the alveolus wall, easy for diffusion.

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15
Q

Type II pneumocytes

a) Shape
b) Function

A

a) Cube-shaped
b) Secrete pulmonary surfactant to reduce surface tension and moist surface
c) Able to differentiate into Type 1 pneumocytes.

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16
Q

Causes of lung cancer

A

a) Intrinsic: Genetics / Age / Certain diseases

b) Extrinsic: Smoking / Asbestos / Radiation exposure

17
Q

Consequences of lung cancer

A

a) Uncontrolled cell proliferation, leading to tumors

b) Coughing blood / Wheezing / Weight loss

18
Q

Causes of Emphysema

A

a) Chemicals in cigarettes damage the alveoli
b) Phagocytes release elastase as part of immune response
c) Elastase destroys the elastic fibers in the alveolar walls
d) Huge air spaces develop in the lungs.

19
Q

Consequences of Emphysema

A

a) Abnormal enlargement of alveoli (lowering SA)

b) Shortness of breath / Expansion of ribcage