topic 5- heritability Flashcards
what is heritability?
An estimate of the average proportion of variance in any behaviour thought to be accounted for by genetic factors across the population
aka how much phenotypic variance is attributable to genotypic variance
what is the additive assumption?
the assumption that argues there are only two components that determine phenotype:
- the genetic part
- the environment
- these will always add up to 100% of variance in a phenotype
what is shared enviroment?
- environmental variation which is shared with family members
what is an example of how heritability changes?
- the heritability of height is increasing with each generation
- this is because environmental influences are causing less variation as there is more equality in things such as nutrition and living conditions
what is the heritability formula?
H^2 = 2( rmz - rdz)
what is the concordance rates for IQ and how is this used to get a heritability estimate
MZ = 86% concordance DZ = 55% concordance
therefore there is a 0.62 heritability
what are examples of residual effects impacting concordance rates?
non shared enviroment, errors of measurement, developmental accidents, G x E interactions
What was Galtons observations of judges on the English bench
- 286 judges were appointed to the english bench between 1660 and 1865
- 109 had one or more relatives who were also ‘emminent’
What was Galtons adoption study?
- He compared sons of emminent men with adopted sons
- adopted sons were much less likely to achieve emminence than the natural sons were
- “the social helps are the same but hereditary gifts are wanting”
who was the founding president of the British Eugenics society?
Galton
what is the heritability of each FFM trait?
Extraversion- 56% Neuroticism- 80% Aggreableness- 46% Contientiousness- 72% Openness- 38%
what was Loehlin et al’s adoption study?
- compared personality dimensions between adoptive children and their biological and adoptive parents
- there was a stronger correlation between child and biological parent than there was child and adoptive parent
What was Pederson et als twi study?
- studied twins reared together and twins reared apart
- for extraversion, the concordence for identical twins reared apart was higher than the concordence for non identical twins reared together or apart.
(further results in 5.4 lecture 2)
what is narrow heritability?
- the fraction of the phenotype that is only due to additive genetic variance
- additive genetic variance is the variance explained by the sum of different gene variations that are involved
what does broad heritability include?
additive genetic variance
dominant genetic variance
epistatic genetic variance