Topic 3B (part 2) - More exchange and transport systems Flashcards
Look at questions about interpreting data on the cardiac cycle
IN BOOK
How are atheromas formed?
DIAGRAM
- The wall of an artery is made up of several layers
- The endothelium (inner lining) is usually smooth and unbroken
- If damage occurs to endothelium (by high blood pressure), white blood cells (mostly macrophages) and lipids from blood, clump together under lining to form fatty streaks
- Over time, more white blood cells, lipids and connective tissue build up and harden to form a fibrous plaque called an atheroma
Why are atheromas harmful?
They partially block lumen of artery and restrict blood flow, which causes blood pressure to rise
When does CVD occur?
When the coronary arteries have too many atheromas, which restricts blood flow to the heart muscle. This can lead to myocardial infarction
What do atheromas increase the risk of?
- Aneurysm - balloon like swelling of the artery
2. Thrombosis - formation of a blood clot
How can atheromas increase the risk of an aneurysm?
- Atheroma plaques damage, weaken and narrow arteries, increasing blood pressure
- When blood travels through weakened artery at high pressure, it may push the inner layers of the artery through the outer layer to form a balloon-like swelling - an aneurysm
- This aneurysm may burst, causing a haemorrhage
How can atheromas increase the risk of thrombosis?
- Atheroma plaque can rupture artery’s endothelium, damaging artery walls and leaving a rough surface
- Platelets and fibrin (a protein) accumulate at site of damage and forms a blood clot (a thrombus)
- This blood clot can cause total blockage of artery, or it can become dislodged and block a blood vessel elsewhere in the body
- Debris from the rupture can cause another blood clot to form further down the artery
How does a myocardial infarction (heart attack) occur?
- Heart is supplied with blood by coronary arteries
- Blood contains O2 needed for heart muscle cells to carry out respiration
- If coronary artery is blocked,area of heart muscle will be totally cut off from blood supply, receiving no O2
What can a heart attack lead to?
Heart failure, which can be fatal
What are symptoms of a heart attack?
- Shortness of breath
2. Sweating
What are the 2 most common risk facts for CVD?`
- Lifestyle factors e.g. smoking, bad diet.
2. Genetic predispositions e.g. age/sex Diabetes type 1
How can high blood cholesterol increase the risk of CVD?
- Cholesterol is one of main constituents of fatty deposits that form atheromas
- Atheromas can lead to increased blood pressure and blood clots
- This can block flow of blood to coronary arteries, which can cause a myocardial infarction
How can a poor diet increase the risk of CVD?
- It is associated with high blood cholesterol levels
2. A diet high in salt increases risk of CVD as it increases the risk of high blood pressure
How can cigarette smoking increase the risk of CVD?
- Nicotine and CO, in cigarette smoke, increase risk of CVD
- Nicotine increases risk of high blood pressure
- CO combines with Haemoglobin and reduced amount of O2 transported in blood, and so reduces the amount of 02 available to tissues Not enough O2 = heart attack - Smoking decreases amount of antioxidants in blood - these are important in protecting cells from damage. Fewer antioxidants means cell damage in coronary artery walls is more likely, which can lead to atheroma formation
How can high blood pressure increase the risk of CVD?
It increases risk of damage to artery walls - so increases risk of atheroma formation and blood clots
- A blood clot could block flow of blood to heart muscle, leading to myocardial infarction. Therefore, anything that increases blood pressure, ,increases risk of CVD (e.g. being overweight, drinking too much, not exercising)
How can age/sex increase the risk of CVD?
Age - risk naturally increases with age
Sex - men are more at risk than women
What risk factors are in/out of our control?
- In our control: smoking, poor diet
- Out of our control: Genetic predispositions to CVD or having high blood pressure as result of another condition e.g. diabetes
Do questions on intepreting data on risk factors and cardiovascular disease
(DIAGRAM)
question of pg 77
What are the 2 different mass transport systems in plants?
- Xylem
2. Phloem
What is the function of the xylem tissue?
The xylem tissue transports water and mineral ions in solution
- These substances move up the plant from roots to leaves
What is the function of the phloem tissue?
The phloem tissue transports organic substances like sugars both up and down the plant
What is a mass transport system?
A system that allows substances to travel over large distances