topic 3 - genetics Flashcards

1
Q

what are the advantages of sexual reproduction?

A

-produce variation (due to genetic variation)
-survival advantage by natural selection
-> sped up by humans in selective breeding

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2
Q

what are the disadvantages of sexual reproduction?

A

-lots of time and energy needed to find a mate
-not possible for isolated individual to reproduce

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3
Q

what are the advantages of asexual reproduction?

A

-only 1 parent needed -> more energy and time efficient (no wasted gametes)
-more reliable offspring
-identical offspring - can be produced in favourable conditions

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4
Q

what are the disadvantages of asexual reproduction?

A

-doesn’t lead to genetic variation in population
-species may only be suited to 1 habitat
-disease may affect all individuals

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5
Q

what are gametes?

A

sex cells (sperm and egg)

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6
Q

what is a zygote?

A

fertilized egg

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7
Q

what are the stages of mitosis?

A

IPMATC

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8
Q

what is DNA organised into in the nucleus?

A

chromosomes

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9
Q

how many chromosomes do normal body cells have?

A

46 - diploid

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10
Q

how many chromosomes do gametes have?

A

23 - haploid

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11
Q

what is meiosis?

A

type of cell division that results in 2 daughter cells - each with half the number of chromosomes of the parent cells (production of gametes)

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12
Q

describe meiosis?

A

-DNA duplicates
-divides into 2 cells - each have 1 full set of DNA
-cross over occurs - mixes DNA of mother and father
-second division occurs - leaves 4 genetically different daughter cells each with half set of DNA - making them haploid (1n)

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13
Q

how many chromatids are in 2 replicated chromosomes after meiosis?

A

4 sister chromatids

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14
Q

what is meiosis’ role in sexual reproduction and growth of the embryo?

A

-meiosis needed to form gametes
-these fuse to from zygote
-zygote divides by mitosis to form embryo

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15
Q

what is the genome?

A

entire genetic material of an organism

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16
Q

what is a gene?

A

short section of DNA that instructs for a particular protein

17
Q

what is DNA?

A

deoxyribonucleic acid - polymer of nucleotides made up of 2 strands that form a double helix

18
Q

what are the bases of DNA?

A

C, G, A, T

19
Q

what are the pairs of bases?

A

C with G and A with T

20
Q

what is the structure of DNA?

A

-polymer - joined by nucleotides - sugar phosphate backbone
-2 strands coil to form a double helix
-linked by series of complementary bases joined by weak hydrogen bonds

21
Q

what is the hydrogen bonding rule for the base pairs?

A

C bonds to G with 3 hydrogen bonds
A bonds to T with 2 hydrogen bonds

22
Q

how can DNA be extracted from fruit cells?

A
  1. mash strawberries in beaker containing detergent and salt
  2. detergent breaks down cell membranes releasing DNA - salt clumps DNA together
  3. filter mixture to get froth and big insoluble bits of cell out
  4. add ice-cold ethanol slowly stop when as much has been added as there is filtrate
  5. DNA insoluble in cold ethanol so will appear as a stringy white precipitate
23
Q

what does the DNA base sequence code for?

A

sequence of amino acids in the polypeptide chain of a protein which fold to produce specifically shaped proteins (e.g. enzymes)

24
Q

where does protein synthesis occur?

A

ribosomes but DNA is too large to leave nucleus so has to go through transcription

25
Q

what is transcription?

A

where bases in DNA is used to make small, single strand of mRNA

26
Q

what bases does RNA use?

A

C, G, A, U - instead of T

27
Q

describe transcription

A
  1. section of DNA (gene) unwinds and unzips (hydrogen bonds between 2 stands breaks)
  2. RNA nucleotides bind to exposed bases on template strand - RNA polymerase joins
  3. forms mRNA - complementary to template strand + matches coding strand (but RNA)
  4. mRNA leaves nucleus to go to ribosomes
  5. 2 strands of DNA join back up
28
Q

describe translation

A
  1. first mRNA codon is read and a tRNA molecule with complementary anticodon binds bringing the first amino acid
  2. next codon read and tRNA with complementary anti-codon binds with 2nd amino acid - peptide bond forms between amino acids
  3. only 2 tRNA’s can attach at a time so first one leaves and is free to collect another amino acid
  4. chain grows as process continues and ribosome moves down mRNA
  5. polypeptide formed