Topic 2 - Structure and Replication of DNA Flashcards
What makes up a DNA strand?
Nucleotides
Structure of a nucleotide in DNA
Deoxyribose sugar, phosphate and sugar
Structure of a DNA strand
Sugar Phosphate Backbone with complementary base pairing
Bases and who they’re paired with in DNA
Adenine and Thymine, Cytosine and Guanine
What bond holds the DNA strands together
Hydrogen Bonds
Is the DNA strand parallel or antiparallel?
Antiparallel
How would you describe the antiparallel structure of the strands?
Deoxyribose and Phosphate at a 3’ end and a 5’ end at each strand
What does DNA store for the person and where is it stored?
Genetic Information and in the base sequence of DNA
The genotype
Determined by the sequence of DNA bases
What is the structure of Chromosomes?
Tightly coiled DNA and are packaged with associated proteins
What is required to start DNA Replication?
DNA Polymerase and a primer
What is the first stage of DNA Replication?
The DNA is unwound and unzipped to form two template strands
What end does the complementary DNA nucleotides get added to on the DNA Strand?
The 3’ end
What happens to the 5’ end during DNA Replication?
The strand is copied in fragments and joined together in fragments
DNA Polymerase
This catalyses the formation of the sugar phosphate backbone in the daughter strand