topic 13 Flashcards
hypoxia
inadequate oxygen to tissue
ischemia
inadequate blood to tissue
type 1 morbid neuroligical outcome
cerebral death, non fatal strokes, new tia
type 2 morbid neuroligical outcome
new intellectual deterioration, new seizures upon discharge
type 1 predictors
70 4-9%risk, aortic atherosclerosis, hisory of prior neurological events-15% carotid stenosis
type 2 predictors
Low cardiac output states Atrial arrhythmias Systolic Hypertension Diabetes
Pulmonary Disease Excessive Alcoholism
neuro impairment
6.1%
post op delireum
10-60%
transient dysfunction
7-44%
permanent complications
1.6-23%
highest neurological risk during surgery
filling heart
how do perfusionist contribute to neuro injury
Focal Embolism Air Plaque Microemboli Left ventricular thrombus Fat Debris Hypoperfusion Inflammation Global Complete CardiacArrest Deep Hypothermic Circulatory Arrest Incomplete Hypotension Inadequate CPB flow
inflammation
ischemia reperfusion injury causes activation of leukocytes
vascular integrity causes foreign surface capillary plugging and liberation of free radical
tailoring o2 delivery
MAP, CO2,CI AND pump flow, HCT, mechanical issue
tailoring O2 consumption
anesthetic agent and depth temperature
brain monitoring
neuro exam, BP monitoring, EEG, Bispectral index, transcranial doppler, intra cranial monitoring, sat. of jugular venous O, venous sat. global, regional sat. of O2
EEG
records elec. activity of brain, 10-20 eectrodes or 2-4 leads, FTPO, odd # left hemi., even right hemi
alpha
8-13 hz. amp is medium,occipital, ralaxed awake
beta
13-30 hz, amp is low, frontal, alert awake
theta
4-8 hz., amp is high, diffuse, sleeping infant or child