Top Hats Flashcards

1
Q

A point mutation (change in a single nucleotide base) is likely to have the most severe impact on gene function when it occurs in which region:

A

The exon

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2
Q

Considering the influence of U1 snRNA on transcription, what would you predict the impact on gene expression to be if the length of the first exon of a gene is increased?

A

Less expression

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3
Q

Why is the prokaryotic ribosome inhibitor clindamycin used to treat infections with certain eukaryotic protozoan parasites?

A

These protozoan parasites possess both eukaryotic and prokaryotic ribosomes.

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4
Q

Most mitochondrial diseases are caused by mutations in the ___________ genome.

A

Nuclear

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5
Q

Based on our discussion thus far about the cytoskeleton, what cell division defects would result from inhibiting actin polymerization?

A

Failure to separate a dividing cell into two distinct daughter cells.

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6
Q

What is correct for a protein destined to be inserted into the plasma membrane?

A

It would traffic through the constitutive exocytosis pathway.

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7
Q

The permeability of a membrane to a particular ion is dependent upon which of the following?

A

The presence of open channels in that membrane.

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