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Top drugs > Top Drugs 2019 > Flashcards

Top Drugs 2019 Flashcards

1
Q

Donezepril

A

Aricept
Anti cholinesterase
For dementia / Alzheimer’s

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2
Q

Vorapaxar

A

Zontivity
Par-1 inhibitor
With low dose aspirin and - or Clopidogrel for secondary prevention of post mi or pad

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3
Q

Verelan

A

Verapamil

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4
Q

Plavix

A

Clopidogrel

Irreversibly blocks p2y12

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5
Q

Risk

A 
= (# patients unfavorable event)/
# in group
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6
Q

Latanoprost

A

Xalatan

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7
Q

Activase

A

Thrombolytic
Tpa
Produces fibrinolysis

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8
Q

Pristiq.

A

Devenslafaxine

SNRI

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9
Q

Exforge

A

Amlodipine/Valsartan

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10
Q

Dilt-XR

A

Diltiazem

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11
Q

Azilsartan

A

Edarbi.

ARB

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12
Q

Clopidogrel

A 
Plavix
Irreversible p2y12
Loading dose 300-600 mg then 75 mg PO we’d
Cyp2c19 enzymes convert to prodrug
D/c 5 days prior to surgery
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13
Q

Hydrocortisone, topical

A

Cory’s is

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14
Q

AScVD risk patients >= 20%

A

Who do not achieve ldl <= 70%

Add ezetimibe with statin

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15
Q

Inhaled corticosteroids

A

Beclomethasone (QVAR)
Budesonide (Pulmicort flexhaler)
Fluticasone ( Flovent HFA)

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16
Q

Interferon 1b

Betaseron. Extavia.

A

Room temp
SQ every other day
Flu like symptoms

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17
Q

Diazepam

A

Valium

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18
Q

Ariprazole

A

Ability

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19
Q

Methotrexate

A

Trexall
MOA: inhibits dihydrofolic acid
Inhibits purine and thymidyl acid
Interferes with DNA synthesis repair and cellular respiration S phase

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20
Q

Fluticasone

A

Flovent HFA, Flovent discus, Arnuity Elliott, Armonair respiclick

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21
Q

Twynsta

A

Amlodipine & telmisartan

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22
Q

Ocrelizumab

A

Ocrevus

Once every 6 mos.

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23
Q

Tiazac

A

Diltiazem

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24
Q

Evolocumab

A

Repatha.
Dec ldl
Psk9 inhibitors

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25
Q

Formoterol & mometasone

A

Dulera

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26
Q

Prestalia

A

Amlodipine & perindopril

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27
Q

Dolasetron

A

Anzemet

Anti emetic

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28
Q

Ca carbonate

Ca citrate

A

Ca carbonate .40 elemental Ca

Ca citrate.21 elemental iron

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29
Q

Folic acid

A

Vitamin B9

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30
Q

Dexamethasone

A

De pal

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31
Q

Lisinopril

A

Prinivil, Zestril,Qbrelis oral solution

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32
Q

Anti coagulants

A

Prevent fibrin formation

Glue between platelets

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33
Q

Colestipol

A

Coke stud
Bile acid sequestant
Dec ldl

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34
Q

Atorvastatin

A

Lipitor

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35
Q

Estradiol patch

A

Vivelle dot
Alora.
Climara
Estrogen

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36
Q

Silodosin

A

Rapaflo

Bph

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37
Q

Methylphenidate

A

Medrol
MOA: unknown
May block reuptake Norepinephrine & Dopamine into presumptive neurons

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38
Q

Losartan/HCTZ

A

Hyzaar

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39
Q

Duloxetine

A

Cymbalta
SNRI
Anti-depressant

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40
Q

Doxepin

A

Silenor.

TCA.

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41
Q

Albuterol

A

Proair hfa, proair respiclick, Proventil hfa, Ventolin hfa

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42
Q

Dypyridamole

A

Persantine.

Reversible inhibitor of platlet aggregation vasodilator

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43
Q

Ziac

A

Bisoprolol/HCTZ

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44
Q

Irbesartan

A

Avapro

ARB

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45
Q

Adenosine

A

Adenocard
pSVt
T 1/2 <10 seconds

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46
Q

Ciclesonide

A

Alvesco
Prodrug MSU solution
Don’t shake

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47
Q

Olopatadine

A

Pataday/ patanol.

Antihistamines ophthalmic

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48
Q

Benazepril

A

Lotensin

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49
Q

Ciprofloxacin

A

Cipro

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50
Q

Formoterol /Budesonide

A

Symbicort

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51
Q

Teriflunomide

A 
Aubagio
PO QD
Ms
Preg. Cat X
Hepatotoxic
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52
Q

Buprenorphine/Naloxone

A

Suboxone (SL film)
Bunavail (buccal film)
Zubsolv (SL tablet)

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53
Q

Premarin, conjugated

A

Premarin

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54
Q

Doxazosin

A

Cardura.

Bph & HTN

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55
Q

Argatroban.

A

Direct thrombin inhibitor

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56
Q

Mupirocin, topical

A

Bactroban

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57
Q

Simvastatin

A

Zocor

Ezetimibe & Simvastatin (Vytorin)

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58
Q

Losartan

A

Cozaar

ARB

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59
Q

Candesartan

A

Atacand

Arb

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60
Q

GoNitro

A

Nitroglycerin sublingual powder

GoNitro

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61
Q

Fluticasone propionate

A

Flonase allergy relief

Veramyst

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62
Q

Doxycyclomine

A

Ventolin

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63
Q

Fluticasone furoate/ Vilanterol

A

Breo. ellipta.

LABA

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64
Q

Ipratropium & Albuterol

A

Nebulized solution

Duoneb

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65
Q

Entresto

A

Sacubitril. &. valsartan

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66
Q

Buspirone

A

Buspar

Anti anxiety

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67
Q

Duragesic

A

Fentanyl patch

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68
Q

Diohenoxylate/Atropine

A

Lomotil

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69
Q

Vasotec

A

Enalapril

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70
Q

Escitalopram

A

Lexapro
SSRI
Anti depressant

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71
Q

Ezetimibe

A

Zetia.

Inhibits cholesterol absorption from intestinal brush border

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72
Q

Flovent

A

Fluticasone inhaler

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73
Q

Liraglutide

A

Victoza, ,Saxenda

Analog GLP-1 increases insulin secretion due to elevated glucose

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74
Q

Ezetimibe & Simvastatin

A

Vytorin

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75
Q

Insulin Lispro

A

Humalog

Humalog kwickpen

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76
Q

Insulin Detemir

A

Levemir, Levemir flextouch

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77
Q

Omega-3-acid

A

Lovaza

Fish oil epa/DHA

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78
Q

Doxazosin Ext Release

A

Carders xl

Bph only

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79
Q

Montelukast

A

Singulair

Anti leukotriene

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80
Q

Fenofibrate

A

PPAR alpha activators

Decrease Tgk

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81
Q

Acetaminophen/codeine

A

Tylenol #2,#3, #4

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82
Q

Sildenafil

A

Viagra

Revatio. PAH

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83
Q

Cymbalta

A

Duloxetine

SNRI

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84
Q

Lotrel

A

Amlodipine & benazepril

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85
Q

Ivabradine

A

Corlanor
Stable resting HR > 70 bpm
Systolic HF

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86
Q

Atomoxetene

A

Strateera.

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87
Q

Fenoldopam

A

Corlopam

Good for renal HTN emergency

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88
Q

Clonazepam

A

Klonopin

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89
Q

Exforge

A

Amlodipine & valsartan

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90
Q

Levetiracetam

A

Keppra

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91
Q

Nitrostat

A

Nitroglycerin sublingual

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92
Q

Methylprednisolone

A

Medrol

MOA: potent glucocorticoid.

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93
Q

Liptruzet

A

Atorvastatin & ezetimibe

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94
Q

Diltiazem

A

Cardizem,cardizem cd, cardizem la, cartia XT, tiazac

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95
Q

Vardenafil

A

Levitra.

Staxyn-ODT

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96
Q

Asamex

A

Mometasone

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97
Q

Cardiogenic. Shock

A

Dobutamine

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98
Q

Revefenacin

A

Yupeiri

QD nebulizer

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99
Q

Integrillin

A

Eptibatide
Anti platelet.
Blocks binding of fibrinogen - glycoproteins
2b/3a

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100
Q

Betrixaban

A

Bevyxxa
VTE prophylaxis
XA inhibitor

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101
Q

Felodipine

A

Plendil XR QD

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102
Q

Propranolol

A

Inderal

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103
Q

Bosentan

A

Tracleer

Pulmonary artery HTN

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104
Q

Insulin Glargine

A

Lantus, lantus solostar , to undo solostar

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105
Q

Salmeterol & fluticasone

A

Airduo respiclick

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106
Q

Epinephrine

A

Epipen. Epipen Jr. , Adrenaclick.

  1. 3 mg/0.3 ml
  2. 15 mg/ 0.15 ml
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107
Q

Ivabridine

A

Corlanor
Selective sinus node inhibitor
Slows HR without causing drop in BP

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108
Q

Metoprolol succinate ER

A

Toprol XR

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109
Q

Terazosin

A

Hytrin

BPH & HTN

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110
Q

RR

Relative risk

A

(Risk in Trt Grp)/(Risk in Control Grp)

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111
Q

Milrinone

A

Primacor
IV
Ionotropic class iii & IV
+ ionotrope and vasodilator

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112
Q

Celecoxib

A

Celebrex

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113
Q

Exforge

A

Amlodipine & Valsartan

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114
Q

Prazosin

A

Minipress HTN only

Alpha-1 blocker

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115
Q

Bromphenitamine
Pseudoephedrine
Dextromethorphan

A

Bromfed DM

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116
Q

Epoprostenol

A

Flolan IV
Treprostinil (tivaso! IV, SC, PO, inhalation)
Dilated pulmonary arteries & helps prevent blood clots
Inhibit platlet function

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117
Q

Nesititide

A

Nature or

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118
Q

Bivalrudin

A

Direct thrombin inhibitor

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119
Q

Ipratropium

A

Atrovent hfa QID

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120
Q

Ambrisenten

A

Letairis!
Oral
Birth defects

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121
Q

Benzonatate

A

Tessalon Perles

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122
Q

Metoprolol succinate

A

Topril xL

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123
Q

Naproxen high dose

A

N/a

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124
Q

Alrmtuzumab

A

Lemtrada
Relapsing MS IV

IV 5 consecutive days year 1
IV 3 consecutive days year 2

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125
Q

Fluoxetine

A

Prozac, Saracen
Major depressive disorder
OCD
SSRI

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126
Q

CI includes 1

A

Not statistically significant

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127
Q

Ezetimibe

A

Zetia.

Inhibits cholesterol absorption in small intestine

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128
Q

Edoxaban

A

Savaysa
No if crcl > 95 ml/min
XA inhibitor

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129
Q

Mitroxantrone

A

IV
Lifetime dose 140 mg/m**2
Cardiac s/E

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130
Q

Cytomel

A

Synthetic thyroid hormone

Liothyronine

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131
Q

LABA

Long acting beta agonist

A

Salmeterol (Serevent discus)

Both asthma and cops

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132
Q

Tasting XT

A

Diltiazem

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133
Q

Patients benefit high intensity statin?

A

High intensity statin
LDL >=190 mg/dL
Or
AScVD risk > 20%

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134
Q

Salmeterol & fluticasone

A

Advair
LABA & steroid
100/50, 250/50, 500/50
No changes is steroid

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135
Q

Icosapent ethyl

A

Vascepa

Fish oil

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136
Q

Lotrel

A

Amlodipine/benezepril

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137
Q

Azithromycin

A

Zithromax
Azithromax Z-pak
Zmax

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138
Q

Reopro

A

Abciximab

2b/3a

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139
Q

Enalapril

A

Vasotec, epaned IV

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140
Q

Lamotrigine

A

Lamictal, lamictal odt, lamictal starter kit

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141
Q

Bimatoprost

A

Lumigan, Latisse

Antiglacoma

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142
Q

Acludinium

A

Tur Diaz pressair
Bid
Dry powder inhaler

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143
Q

Merperidine

A

Demerol

50-150 mg IM/Sq/PO q 3-4 hrs

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144
Q

Albuterol/Ipratropium

A

Combivent Respimat

Albuterol beta 2 agonist bronchodilator

Ipratropium anitcholinergic

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145
Q

LAMA

Long acting muscarinic antagonist

A

Tiotropium
Spiriva respimat asthma
Spiriva handihaler respimat cops

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146
Q

Amturnide

A

Amlodipine aliskiren HCTZ

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147
Q

Abciximab

A 
IV Reopro
Mouse antibody
Gp2b3a
Adjunct to pci
Must use filter do not shake vial
No renal adjustments needed
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148
Q

Nortriptyline

A

Pamelor.

TcA

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149
Q

Penbutolol

A

Levatol

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150
Q

Cartelolol

A

Ophthalmic only

Beta blocker

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151
Q

RCT

Randomized control trial

A

Compares experimental treatment to control [placebp]

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152
Q

Eszopiclone

A

Lunesta

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153
Q

Alirocumab

A

Praluent sq psk9 inhibitors

Dec ldl

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154
Q

Nystatin

A

Bio-Statin

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155
Q

Empaglifloxin

A

Jardiance

SGLT2 inhibitors

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156
Q

Betaxolol

A

Kerlone
Ophthalmic Betoptic-S
Beta blocker

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157
Q

Alvesco

A

Ciclesonide

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158
Q

Estradiol topical/ring

A

Estrace
Earring
Vagifem

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159
Q

Nifedipine

A

Procardia xl, adalat cc

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160
Q

Ca corrected

A

= Ca serum + [(4- Albumin) * 0.8]

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161
Q

Diltiazem

A

Cardizem, Tiazac

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162
Q

BIdIL

A

Hydralazine & isorbide dinitrate TiD

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163
Q

Insulin Aspart

A

Novolog

Novolog Pen

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164
Q

Nitroglycerin

A

Nitrostat, Nitrolingual, NitroMist

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165
Q

Benztropine

A

Cogentin
Anti Parkinson’s
Anticholinergic

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166
Q

Telmisartan

A

Micardis

ARB

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167
Q

Gemfibrozil

A

Lipid
Decreased fatty acid uptake hepatic
Increases HDL.

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168
Q

HCTZ

A

Microzide

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169
Q

Nicardipine

A

Cardene IV

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170
Q

Sotolol

A

Betapace

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171
Q

Lovenox

A

1 mg/kg SQ q12 or

1.5 mg/kg we

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172
Q

Lorazepam

A

Ativan
Benzodiazepine
Increases GABA inhibitor neurotransmitter

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173
Q

Alfuzosin ext release

A

Uroxatral

Bph

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174
Q

Digoxin levels

A

A fib 0.8 - 2.0

CHF 0.5 - 0.8

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175
Q

Triamterene/HCTZ

A

Maxzide/Maczide 25,Dyazide

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176
Q

Budesonide

A

Pulmicort respules

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177
Q

Butalbital/acetaminophen/ caffeine

A

Fioricet

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178
Q

Bisoprolol

A

Zebeta

Beta blocker

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179
Q

Nitrofurantoin

A

Macrobid, Macrodantin

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180
Q

Inducers

A 
Phenytoin
Smoking
Phenobarbitals 
Oxcarbezapine
Rifampin
Carmezapinr
St. John’s wart

Psporcs

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181
Q

Docusate

A

Colace

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182
Q

Tadalafil

A

Cialis

Adcirca. pAH

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183
Q

Hydromorphone

A

Dilaudid

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184
Q

Ipratropium & Albuterol

A

Combivent respimat

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185
Q

Antiplatelets

A

Prevent platlet. Aggregation

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186
Q

Ethinyl estradiol/ norethinddrone FE

A

Junel. Loestrin

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187
Q

Losartan/HCTZ

A

Hyzaar

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188
Q

Digoxin

A

Digital, Lanoxin

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189
Q

Amiodarone

A

Pacerone

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190
Q

Methadone

A

dolophine.
Narcotic agonist-analgesic of opiate receptors; inhibits ascending pain pathways, thus altering perception and response to pain; produces analgesia, respiratory depression, and sedation

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191
Q

Mirtazapine

A

Remeron,remeron Zoltan

MOA: tetracyclic structure different than SSRIs TCAs MAOIS THRU ITS CENTRAL PRESYNATIC ALPha 2 adrenergic antagonist effects
Stimulates norepi, seretonin release

Indications: major depressive disorder
Off label insomnia

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192
Q

Fenofibrate

A

Fibrin acid derivative

Lower TG

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193
Q

Linaclotide

A

Linzess.
Irritable bowel syndrome
Chronic idiopathic constipation

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194
Q

Isradipine bid

A

Dynacirc

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195
Q

Citalopram

A

Celexa

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196
Q

Olmesartan

A

Benicar

ARB

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197
Q

Avanafil

A

Stendra.

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198
Q

Nadolol

A

Corgard

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199
Q

Salmeterol

A

Serevent

LABA

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200
Q

Sildenafil

A

Viagra, Revatio (PAH)

Thanks again

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201
Q

Nisoldipine

A

Sular

Extended release tabs

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202
Q

Levocetirizine

A

Xyzal

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203
Q

Medroxyprogesterone

A

Provera.
Amenorrhea
Contraception
Endometrial hyperplasia

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204
Q

Amlodipine

A

Norvasc

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205
Q

Zafirlukast

A

Accolate

Anti-leukotriene

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206
Q

Carbidopa/levodopa

A

Sinemet

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207
Q

Ramipril

A

Altace only caps

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208
Q

Ofloxacin.

A

Ocuflox
Fluroquinolone
Inhibits DNA guarded
Inhibits transcriptions

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209
Q

Brillinta

A

Titagrelor

P2y12

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210
Q

Fondaparinux

A

Arixtra
No if Crcl < 30 ml/min
Indirect XA inhibitor

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211
Q

Fluvastatin

A

Lescol(generic)

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212
Q

Clarithromycin

A

Biaxin

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213
Q

Hydrocodone/Acetaminophen

A

Portable, Lorcet, Norco, Vicodin

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214
Q

Atenolol

A

Tenormin

Beta blocker

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215
Q

Neomycin/polymyxin/dexamethasone

A

Maxitrol
MOA: inhibits protein synthesis by binding to 30S ribosomal subunits

Ophthalmic susp/oint for bacterial eye infection

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216
Q

Losartan

A

Cozaar

ARB

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217
Q

Eprosartan

A

Teveten

ARB

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218
Q

Factorial design

A

> 2 groups

Randomizes to more than usual 2 groups to test experimental conditions.

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219
Q

Digoxin

A

Lanoxin, lanoxicaps, digital

+ ionotrope
- chronotropic

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220
Q

Apixaban

A

Eloquis

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221
Q

Eptifibatide

A

Integrillin
Acute coronary syndrome
PCI with or without stents IIb/3A

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222
Q

Loratadine

A

Claritin
2nd gen antihistamine
Selective H1 antagonist activity

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223
Q

Isosorbide dinitrate
Isordil titradose
Bid,tid

A

7 am, noon, 5 pm

Nitrate free interval >= 14 hours

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224
Q

Anion gap

A

Na. - CL. - HCO3

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225
Q

Dulaglutide

A

Trulicity

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226
Q

Atenolol

A

Tenormin

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227
Q

Zileuton

A

Zyflo, Zyflo CR

5-lipoxygenase inhibitor

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228
Q

Hyzaar

A

Losartan & Hydrochlorothiazide

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229
Q

Tranolopril

A

Mavik

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230
Q

Cephalexin

A

Keflex

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231
Q

Lisinopril/HCTZ

A

Zestoretic

232
Q

Metronidazole

A

Flagyl

MOA: inhibits nucleic acid synthesis by disrupting DNA causing strand breakage

Indications: anaerobic bacterial infection/STIs

233
Q

Mometasone/Formoterol

A

Dulera

MOA: glucocorticoid inhaled- mometasone

Formoterol LABA

234
Q

Rosuvastatin

A

Creator most potent

235
Q

Irbesartan

A

Avapro

236
Q

Acyclovir

A

Zovirax

237
Q

Metoprolol Tartrate IR

A

Lopressor

238
Q

Dimethyl fumarate

A 
Tecfidera
Ms 
MOA: antioxidant 
S/E pML flushing
Monitor CBC include lymphocytes count
239
Q

Gemfibrozil

A

Lopid.

240
Q

Cangrelor

A

Kengreal

IV

241
Q

Dabigatran

A

Direct thrombin inhibitor
PO
Pradaxa

242
Q

PH

A

7.35-7.45

243
Q

Beclomethasone

A

QVAR

244
Q

Baclofen

A

Lioresal

245
Q

Beclomethasone

A

QVAR redihaler

246
Q

Fluconazole

A

Diflucan

247
Q

Isordil titradose

Isosorbide dinitrate

A

7am noon 5 pm

Nitrate free period >=14 hrs

248
Q

Hydralazine

A

N/a

249
Q

Cyclosporine

A

Restasis

250
Q

Fosinopril

A

Monopril.

251
Q

Pulmicort

A

Budesonide

252
Q

Glyburide

A

Glynase, Disney’s

Increases insulin secreation beta cells

253
Q

Ketoconazole topical

A

Nizoral, Nizoral A-D (otc)

254
Q

Amlodipine

A

Norvasc

255
Q

QVAR

A

Beclomethasone

256
Q

Rivaroxaban

A

Xarelto
XA inhibitor
10, 15, 20 mg QD

257
Q

Metoprolol tartrate

A

Lopressor

Beta blocker

258
Q

Dexlansoprazole

A

Dexilant

259
Q

Effient.

A

Prasugrel
Anti platlet
P2y12

260
Q

Atenolol/Chlorthalidone

A

Tenoretic

261
Q

Nifedipine ER

A

Adaptation CC, Procardia XL

262
Q

Omega 3 carboxylic acid

A

Eponova

263
Q

Septic shock

A

Levi/ dopamine

264
Q

Ethinyl estradiol and norgestimate

A

Ortho tricyclen, sprinter, trinessa

265
Q

Catapres-TTS

A

Clonidine patch

Change every 7 days

266
Q

Nitroglycerin transdermal patch

A

Mini Tran, Nitro-Dur

267
Q

Acebutolol

A

Sectral
Drug induced lupus
Beta blocker

268
Q

Clevidipine

A

Cleviprex iv

269
Q

Memantine

A

Namenda.
NMDA receptor antagonist
Altzheimer type dementia

270
Q

Famotidine

A

Pepcid

271
Q

Nitroglycerin sublingual spray

A

Nitrolingual, NitroMist
0.4 mg spray
Do not shake container
Must prime pump

Nitrolinual spray 5 times
NitroMist 10 times

Bottle is primed for 5 weeks

272
Q

Spiriva respimat

A

Soft mist inhaler

273
Q

Apixaban

A

eliquis

XA inhibitor

274
Q

Aggreenox

A

Aspirin & ER dypyridamole

Decrease risk of stroke in patients with history of TIA and stroke

275
Q

Effexor

A

Venlafaxine

SNRI

276
Q

Nimodipine

A

Nimotop

277
Q

ARR

Absolute risk reduction

A

(% risk control group - % risk trt grp)

278
Q

ICS/LABA

A

Budesonide/formoterol (symbicort)
Fluticasone/ Salmeterol (Advair HFA, Airduo respiclick)
Mometasone/formoterol (Dulera)
Fluticasone/vilanterol (Breo Elliott)

279
Q

Chlorthalidone

A

Hygroton, thaline

Diuretics thiazides

280
Q

Dextromethorphan/promethazine

A

Promethazine DM

Antitussive/1st gen anti-histamine

281
Q

Doxycycline

A

Vibramycin

282
Q

Meta analysis

A

Combines results from multiple studies

283
Q

Nitroprusside

A

Nipride

284
Q

Peridopril

A

Aceon

285
Q

Apixaban

A

Eliquis.

2.5, 5 mg BID

286
Q

Savella

A

Milnacipram fibromyalgia

SNRI

287
Q

Case report and case series

A

Case report = single patient

Case series = few patients

288
Q

Gemfibrozil

A 
Lopid.
Fibrin acid derivative 
Stimulate enzyme lipoprotein lipase increases the li polis is vldl &amp; dec tG
Before meals 30 min
Inc risk myopathy with statins
May increase warfarin, monitor inr
289
Q

Cardizem

A

Diltiazem

290
Q

Nitroglycerin sublingual tabs

A

Nitrostat
Take SL tabs every 5 minutes for chest pain

If chest pain persists after one dose dial 911

Max 3 SL tabs in 15 minutes

291
Q

Liodexamfetamine

A

Vyvanse

Promotes release dopamine & norepi from presynaptic nerve terminals

292
Q

Absolute Neutophil Count

A

WBC * (%bands + % swag)
_____________________
100

< 1000 neutropenia

293
Q

Aldendronate

A

Fosamax

294
Q

Clindamycin, topical

A

Cleocin, clindagel

295
Q

Pegylated interferon beta 1a

A

Plegridy
Subq. Biweekly 14 days
Relapsing Ms

296
Q

Captopril

A

Capoten TID empty stomach

297
Q

Ethinyl estradiol/ etonogestrel

A

nova ring.

298
Q

Lisinopril

A

Prinivil, Zestril

299
Q

Prasugrel

A

Effluent
60 mg loading dose then 10 mg QD
Use within 30 days stay in original container
Stop 7 days prior to surgery

300
Q

Morphine

A

MSContin, Kadian, Duramorph

301
Q

Canagliflozin

A

Invokana

Sglt2 transport inhibitor

302
Q

Pravastatin

A

Pravachol

303
Q

Cyclobenzaprine

A

Amrix, Fexmid

304
Q

Isordil tabs, Dilatrate Sr caps

A

Isorbide dinitrate

No nitrates if systolic bp < 90 mmHG

305
Q

Tirofiban

A

Aggrastat.

Blocks gp23a

306
Q

Buprenorphine

A

Belbuca (buccal film)

Butrans (patch)

307
Q

Systematic review article

A

Specific topic or answers a question

Ex- the evolving landscape of advanced renal cell carcinoma in patient progression after VEGF inhibition.

308
Q

Erythromycin

A

E.E.S. 400, Ery-Tab

309
Q

Milrinone

A

No brand

For decompensated heart failure

310
Q

Lovastatin

A

Altoprev

311
Q

Guanfacine.

A

Alpha-2 agonist
Decrease sympathetic outflow
ADHD
Mech unknown

312
Q

Furosemide

A

Lasix

313
Q

Heparin induced thrombocytopenia

A

Argatroban.
Bivalridin (Angiomax)
FONDAPARINOX (Arixtra)

314
Q

Niacin

A

Increases risk of myopathy with statins
Dec TC, LDL, VLDL
Inc HDL
Take 325 mg of ASA 30-60 min prior

315
Q

Esmolol

A

Brevibloc

Beta blocker

316
Q

Isotonicity

A

E=(58.5)(I) / (MW)(1.8)

317
Q

Lansoprazole

A

Prevacid, Prevacid 24 hr, Prevacid

Solitaire

318
Q

Cefuroxime

A

Cefdinir

319
Q

Mometasone,topical

A

Elocon

MOA: corticosteroid topical

Indications: dermatitis, pruitus.

320
Q

Matzim LA

A

Diltiazem

321
Q

Tamsulosin

A

Flomax

Bph only

322
Q

Levofloxacin

A

Synthroid, levoxyl, unithroid

323
Q

Cartia XT

A

Diltiazem

324
Q

Tenoretic

A

Atenolol/HCTZ

325
Q

Umeclidinium

A

Incruse Elliott QD

326
Q

Diclofenac topical

A

Voltaren gel

327
Q

Meloxicam

A

Mobic.
MOA: inhibit Cox 1 and 2
NSAID

328
Q

Nitroglycerin ointment 2%

A

NitrBID
Bid
1/2 inch on rising and 1/2 inch 6 hours later
10 - 12 hr nitrate free period

329
Q

Cipro/Dex

A

Ciprodex

330
Q

Bupropion

A

Wellbutrin SR
Wellbutrin XL
Zyban

331
Q

Hypovolemic shock

A

Dopamine / Levophed (norepinephrine)

332
Q

Montelukast

A

Singulair

MOA: leukotriene receptor antagonist

333
Q

Lithium

A

Lithobid
Inhibits reuptake postynaptic D2 sensitivity
Influences reuptake of seratonin & norepinephrine

334
Q

Ketoralac

A

Acular

335
Q

Lovastatin

A

Mevacor, Altocor

336
Q

Total Cholesterol

A

HDL + LDL + (TG/5)

337
Q

Icosqpent ethinyl

A

Vacepa
Fish oil
EPA/DHA

338
Q

Tiotropium

A

Spiriva handihaler

Dry powder inhaler QD

339
Q

Cohort studies

A

Compares outcomes of a group of patients exposed and not exposed. To a treatment.

340
Q

Fluticasone

A

Flovent HFA , Flovent diskcus, Amiity Ellipta.

341
Q

Doxazosin

A

Cardura.

342
Q

Colesevelam

A

Welchol
Bile acid sequestant
Dec ldl

343
Q

Azor

A

Amlodipine & olmesartan

344
Q

Glimepiride

A

Amaryl

Increases secreation insulin beta cells

345
Q

Esomeprazole

A

Nexium, Nexium 24 hr, Nexium IV

PPI

346
Q

Aerospace

A

Brand d/c flunisolone

347
Q

Zyprexa

A

Olanzapine

2nd gen antipsychotic

348
Q

Olmesartan

Olmesartan/HCTZ

A

Benicar.
Arb
—-
Olmesartan/HCTZ benicar hct

349
Q

Carvedilol

A

Coreg

350
Q

Omega3/ ethyl ester

A

Lovaza.

MOa not understood

351
Q

Formoterol & budesonide

A

Symbicort

352
Q

Glipizide

A

Glucotrol
Increases secretion beta cells
Decreases production hepatic glucose

353
Q

Tjrombolytics

A

Break down fibrin

354
Q

Hydrochloroquine

A

Plaquenil

355
Q

Methocarbamol

A

Robaxin
Skeletal muscle relaxant
MOA: unknown possible CNS depression

356
Q

Tarka

A

Verapamil & trandolapril ( w/food)

357
Q

Dabigatran

A

Pradaxa
IIa inhibitor
75, 150 mg bid

358
Q

mOsmol/L

A

Wt/MW * #particles * 1000

G/L/ G/mole

359
Q

Diphenhydramine

A

Benadryl

360
Q

Tnkase.

A

Plasminogen activator

Inhibits fibrinolysis

361
Q

Chlorhexidine topical antiseptic

A

Hibiclens

362
Q

Colesevelan

A

Welchol

Bile acid sequestant excreted in feces

363
Q

Neomycin/ polymyxin/hydrocortisone topical

A

Cortisporin.

364
Q

Fenofibrate

A 
Antora, Tricor, Trilipix
Increases VLDL metabolism 
Fibrin acid agents 
PPAR alpha activator
Inc app lipoprotein C2
365
Q

Devenslafaxine

A

Pristq.

SNRI

366
Q

RRR

Relative risk reduction

A

1 - RR

367
Q

Linagliptin

A

Tradjenta

368
Q

Finasteride

A

Proscar

5 alpha reductase inhibitor

369
Q

Amitriptyline

A

Elavil, endep

370
Q

Linaglip

A

Trajenta

DM2

371
Q

Glatiramer

A

Relapsing MS
Copaxone, Glatopa
SQ daily
Pregnancy cat B

372
Q

Fluocinonide, topical

A

Vanos.
Corticosteroid
Psoriasis

373
Q

Olanzapine

A

Zyprexa

2nd gen antipsychotic

374
Q

Glycopyrolate

A

See bro caps neohaler Bid

375
Q

mmol

A

mg/MW

376
Q

Case control

A

Compares patients without disease (control) to patients with disease (retrospective)

377
Q

Clobetasol, topical

A

Cloned, temovate, Olux

378
Q

Quinipril

A

Accupril

379
Q

Allopurinol

A

Zyloprim, Aloprim

380
Q

Vytorin

A

Simvastatin & ezetimibe

381
Q

Isoptin SR

A

Verapamil

382
Q

Minocycline

A

Mini in,
Class: tetracycline

MOA: inhibits protein synthesis & bacterial growth by binding to 30s and 50s subunits of bacteria

Indications community acquired MRSA
Gonococcal infection males
Chlamydia

383
Q

Metformin

A 
Glucophage 
Glucophage XR
Fortamet
Glumetza
MOA: dec hepatic glucose production
Decrease GI glucose absorption 
Inc. insulin cell sensitivity
384
Q

Valsartan

A

Diovan

ARB

385
Q

CI does not include 0

A

Statistically significant

386
Q

Bisoprolol/HCTZ

A

TIAC

387
Q

Enalapril

A

Vasotec

AceI

388
Q

Metolazone

A

Zaroxlyn

Thiazides Like diuretic

389
Q

Nabymetone

A

NSAID
Relafen.
Inhibits cox1 and cox2

390
Q

Moexipril

A

Univasc empty stomach

391
Q

Isosorbide mononitrate

A

Monoket, ISMO
Bid 8 am & 3 pm

Extended release (imdur.)
QD
Do not use for acute angina

392
Q

Cetirizine

A

Zyrtec

393
Q

Nebivilol

A

Bystolic

Beta blocker

394
Q

Calan SR

A

Verapamil

395
Q

Carisoprodol

A

Soma

396
Q

Pitastatin

A

Livalo

Zypitamag ( with magnesium)

397
Q

Budesonide

A

Pulmicort

Pulmicort flexhaler

398
Q

Verapamil

A

Calan, calan Sr, Verelan, Verelan PM

399
Q

Calan

A

Verapamil

400
Q

Mol

A

g/MW

401
Q

Cholecalciferol

A

Vit D3

402
Q

Gabapentin

A

Neurontin

403
Q

Rivaroxaban

A

Xarelto
No if crcl < 30 ml/min
xA inhibitor

404
Q

Ergo calciferol

A

Vit D2

405
Q

Lovastatin

A

altoprev

406
Q

Divaloroex/Valproate

A

Depakene
Depakote
Anti-convulsants

407
Q

Natalizumab

A

Tysarbri
IV
pML

mS

408
Q

Interferon beta 1a

A

Avonex. Rebif.
Relapsing MS

Avonex IM once weekly
Frig

Rebif sq 3 times weekly
Frig.

409
Q

Ticagrelor

A 
Brillianta.
Reversible bonds p2y12
Stop 5 days prior to surgery 
Aspirin dose above 100 mg 
Reduces effectiveness of Brillinta
Loading dose 180 mg
Maint. Dose 90 mg bid
410
Q

Tekamlo

A

Amlodipine & aliskiren

411
Q

Heparin

A

IV
Loading dose 80 U/ KG

Maint. Dose 18 U/kg/hr

Heparin check APTT every 6 hrs

412
Q

MEQ

A

(Mg x valence) / MW

413
Q

Metaclopramide

A

Regan

MOA: blocks dopamine receptors at high dose and seratonin receptors

414
Q

Glycopyrolate

A

Lingala magnair

Nebulizer

415
Q

Cross over rct

A

Grp 1 receive trt A 1st then crossover to trt B

Grp 2 receive trt B 1st then crossover to try A

416
Q

Cholestyramine

A

Prevalite. Questran.
Bile acid sequestrant
Dec ldl

417
Q

Atorvastatin

A

Lipitor

Caudet = amlodipine & Atorvastatin

418
Q

Digoxin

A

+ionotrope
- chronotrope

Lanoxin. Lanoxicaps. Digitex.

419
Q

Oxycodone ER

A

OxyContin

420
Q

Oxycodone /Acetaminophen

A

Percocet, Endocet

421
Q

Pantoprazole

A

Protonix

422
Q

Paroxetine

A

Paxil

423
Q

Amlodipine & Atorvastatin

A

Caduet.

424
Q

Ezetimibe & Simvastatin

A

Vytorin

425
Q

Fenofibrate

Fenofibric. Acid

A

Antara Tricor trillipix

Fibrates. Ppar alpha activators

426
Q

Gemfibrozil

A

Lopid

Fibrates PPAR alpha activators

427
Q

Colesevelam

A

Welchol
Bile acid sequestant
Binds to bile acids in intestine and excreted in feces

428
Q

Niacin

A

Dec tG and ldl

429
Q

Omega 3 and ethyl esters

A

Lovaza

Icosapent ethyl = vasepa.

Fish oils
MOA: unknown

430
Q

PCSK9 inhibitor

A

Praluent=alirocumab

Evocumab =
Repatha.

Bind to ldl receptors lowering ldl

431
Q

Trituration

A

Mix homogeneous

432
Q

Levigation

A

Tutu ration mortar & pestle inc. liquids

433
Q

Spatulation

A

Similar to levigation but uses a spatula with pint slab

434
Q

Pulverization

A

Crystallization powder do not crush easily

435
Q

Ivacaftor

A

Kalydeco
>= 12 yo G551D mutation
Granular <6 yo and tabs

436
Q

Tezacaftor-ivacaftor

A

Symdecko
>= 12 yo
f608del mutation

437
Q

Luna after-ivacaftor

A

Orkambi
>=2 yo F508del
Granules & tabs

438
Q

Alprostadil.

A

Muse
Prostaglandins E1 vasodilator
Pellet inserted into urethra for E

Caverject - inject corpus cavernossom

439
Q

Lispro.

A

Humalog, Admelog
Room temp 28 days
Humalog U-100 (100 U/ mL)
humalog U-200 (200 U/ mL)

440
Q

Glulisine

A

Apidra.
Room temp 28 days
Rapid acting

441
Q

Refrigerator temp.

A

(2-8 C) or (36-46 F)

442
Q

Insulin

A

29-32 gauge

4 mm needle

443
Q

Interval data

A

No meaningful zero.

Zero doesn’t = none

444
Q

Ratio data

A

Zero meaningful

Zero equals none

445
Q

RR relative risk

A

TG/CG

RR as likely

446
Q

RRR relative risk reduction

A

1-RR

Less likely

447
Q

ARR (absolute risk reduction)

A

(% risk CG) - (% risk TG)

12 out of 100 patients will benefit from treatment

448
Q

Sildenafil

A

Viagra, Revatio (pAH)

PDE/5 inhibitor
Inc camp and inflow of blood inc smooth muscle relaxation

449
Q

Tadalafil

A

Cialis , Adcirca

PDE/5 inhibitor

450
Q

Vardenafil

A

Levitra, Staxyn-ODT

451
Q

Ava after

A

StendrA

452
Q

Oxycodone ER

A

OxyContin
Narcotic agonist - analgesic opiate receptor
Inhibits ascending pain pathways

453
Q

Oxycodone/ acetaminophen

A

Percocet, Endocet

454
Q

Cimetidine

A 
Tagamet
h2RA
Gynecomastia
Drowsiness 
Agitation 
Diahrrea
455
Q

Ranitidine

A

Zantac
IV/IM
H2RA

456
Q

Famotidine

A

Pepcid
IV/oral
h2RA

457
Q

Nizatidine

A

Acid

h2RA

458
Q

Prevpac

A

H.pylori
Amoxicillin
Clarithromycin
Lansiorazole

459
Q

Pylera

A

H.pylori

Bismuth, metronidazole, tetracycline

460
Q

Vimovo

A

Esmoprazole & naproxen

461
Q

Metoclopreamide

A

Replan

Accelerates gastric emptying

462
Q

Yosprala

A

Omeprazole & Asa

463
Q

Prevpac

A

CAL
Clarithromycin
Amoxicillin
Landoprazole

464
Q

Pylera

A

Bismuth
Metronidazole
Tetracycline

465
Q

Chi squared test

A

Nominal or ordinal data

Nominal data - gender & race

Ordinal data - hypoglycemic event severity on a 3 point scale

466
Q

Student t-test

A

Mean Change in A1C example of continuous data

There are 2 groups making a student t test appropriate

467
Q

ANoVA

A

Good for 3 groups

468
Q

Mann Whitney test

A

Data is NOT normally distributed (2 groups)

Wilcox signed rank
1 group with before and after measures

469
Q

Desvenlafaxine

A

SNRI
Pristiq
Depression
Inc bp

470
Q

Venlafaxine

A

Effexor
MDR, gad, panic disorder xr only
Ghost tablet in stool

471
Q

Desvenlafaxine

A

Khedezla
SNRI
For MDR
Max 400 mg/d with or without food

472
Q

Duloxetine

A

Cymbalta
SNRI
Indications:
Depression, gad, diabetic peripheral neuropathy, fibromyalgia, chronic muscle skeletal pain including osteoarthritis and chronic lower back pain.

473
Q

Milnacipram

A

SNRI
Fibromyalgia

3 drugs for fibromyalgia
Lyrics (pregabalin), Cymbalta (duloxetine). & milnacipram (Savella)

474
Q

Levomilnacipram

A

Fetzima
MDD
ESRD: don’t use
Avoid alcohol

475
Q

Fluoxetine

A

SSRI

Prozac

476
Q

Sarafem.

A

Fluoxetine
sSRI
pMDD premenstral dysphoric disorder

477
Q

Paroxetine

A

Paxil’s

SSRI

478
Q

Sertraline

A

Zoloft

SSRI

479
Q

Citalopram

A

Celexa

SSRI

480
Q

Escitalopram

A

Lexapro
SSRI
S-enantomer of Citalopram

481
Q

Phenerzine

A

Nardil

MAOI

482
Q

Isocarboxazid

A

Marplan

MAOI

483
Q

Tranylcypromine

A

Parnate.

MAOI

484
Q

Selegiline

A

Emsam
Patch
MAOI

485
Q

Ariprazole

A

Ability- antioosychotic

Approved for mdd

486
Q

Olanzapine/fluoxetine

A

Symbyax
Approved for mdd
Antipsychotic

487
Q

Quetiapine xr

A

Seroquel xr

488
Q

Brezpiprazole

A

Rexulti
Mdd
Antipsychotic

489
Q

Phentolamine

A

Regitine.
1-phenochromacytoma
2-cocaine Od. HTN crisis
3- MAOI tyramine HTN crisis

490
Q

Pregnancy HTN

A

Merhyldopa, Nifedipine, labetalol

491
Q

Felodapam

A

Corlopam

Renal HTN emergency

492
Q

Ocrelizumab

A

Ocrevus

Primary progressive MS

493
Q

Cartia.

A

Diltiazem

494
Q

Cardizem

A

Diltiazem

495
Q

Dilt-XR

A

Diltiazem

496
Q

Cartia-XR

A

Diltiazem

497
Q

Tiazac

A

Diltiazem

498
Q

Taztia

A

Diltiazem

499
Q

Matzim. LA

A

Diltiazem

500
Q

Calan calan Sr

A

Verapamil

501
Q

Isoptin sr

A

Verapamil

502
Q

Verelan

A

Verapamil

503
Q

Candesartan

A

Atacand

504
Q

Eprosartan

A

Tevetan

505
Q

Irbesartan

A

Avapro

506
Q

Losartan

A

Cozaar

507
Q

Olmesartan

A

Benicar

508
Q

Telmisartan

A

Micartis

509
Q

Valsartan

A

Diovan

510
Q

Azilsartan

A

Dearborn

511
Q

Tenet

A

Guafacine

HTN

512
Q

Intuiv.

A

Guanfacine

ADHD

513
Q

Caduet

A

Amlodipine & Atorvastatin

514
Q

Adapt

A

Nifedipine

515
Q

Milrinone

A

Primacor
Chf
+ ionotrope vasodilator

516
Q

Nesiritide

A

Natrecor.

Diuretic & vasodilator

517
Q

Entresto.

A

Sacubitril & valsartan
36 hour wash out period when switching from ACEI

Systolic bp >100 mmHG

518
Q

Ziac.

A

Bisoprolol & hctz

519
Q

Benicar

A

Olmesartan

520
Q

Treat torsades. De pointe

A

Magnesium IV

521
Q

Fragmin.

A

Dalteparin

2500-5000 U SQ

522
Q

Lovenox

A

Enoxaparin
SQ
Lmwh
Don’t give with pork allergy

523
Q

Idaruzumab

A

Praxbind
Pradaxa antidote
IV

524
Q

Pradaxa.

A

Dabigatran

Once bottle is opened good for 6 mos

525
Q

Anti-coagulant

A

Blood thinners inhibit clotting factors

526
Q

Anti-platlets

A

Inhibit enzymes that cause platlets yo clump together

527
Q

Ranolazine

A

Renexa
For angina
Doesn’t lower BP or HR

528
Q

Danazol

A

No generic
Androgen
For endometriosis

529
Q

Liptruzet

A

Atorvastatin & ezetimibe

530
Q

Salmeterol & Fluticasone

A

Advair

LABA & steroid

531
Q

Formoterol & budesonide

A

Symbicort

LABA & steroid

532
Q

Formoterol & mometasone

A

Dulera

LABA & steriod

533
Q

Salmeterol & fluticasone

A

Airduo respiclick

LABA & steriod

534
Q

Salmeterol

A

Serevent diskus

535
Q

Salmeterol & fluticasone

A

Advair

536
Q

Dulera

A

Formoterol & momentasone

537
Q

Symbicort

A

Formoterol & budesonide

538
Q

Airduo respiclick

A

Salmeterol & fluticasone

539
Q

Ipratropium

A

Atrovent HFA

540
Q

Ipratropium & Albuterol

A

Combivent respimat

541
Q

Ipratropium & Albuterol nebulizer

A

Duoneb

542
Q

Tiotropium

A

Spiriva handihaler dry powder QD

543
Q

Tiotropium respimat

A

Soft mist inhaler
Spiriva respimat
pTOP
Prime-Turn—Open-Press

544
Q

Umeclidinium

A

Incruse Elliott QD

545
Q

Aclidinium

A

Tudorza pressair dry powder

546
Q

Glycopyrolate

A

Seebri caps in neohaler

547
Q

Glycopyrolate

A

Lingala magnair nebulizer

548
Q

Revefenacin

A

Yuperli

QD nebulizer

549
Q

Spiriva

A

Tiotropium
Anticholinergic
Dry mouth

550
Q

Nucala

A

Mepolizumab
Blocks IL5
For asthma

551
Q

Norco

A

Hydrocodone & acetaminophen

552
Q

Lorcet

A

Hydrocodone & acetaminophen

553
Q

Lortab

A

Hydrocodone & acetaminophen

554
Q

Vicodin

A

Hydrocodone & acetaminophen

555
Q

Yosprala

A

Aspirin and omeprazole

556
Q

Cerebyx

A

Fosphenytoin

557
Q

Zanaflex

A

Tizanidine

Alpha 2 agonists

558
Q

Vimovo

A

Naproxen & esomeprazole

559
Q

Buspar

A

Buspirone
Anti-anxiety
High affinity for seratonin 5ht1 & 2

560
Q

Clobetasol

A

Clobetasol
Temovate
Olux.
Topical corticosteroids

561
Q

Ergo calciferol

A

Vit D2

Calciferol

562
Q

Estradiol patch

A

Vivelle dot
Alora
Climera

563
Q

Bosentan

A

Tracleer
Oral
PAH

564
Q

Ambrisartan

A

Letaris.
Oral
Birth defects
pAH

565
Q

Eprostenol

A

Flolan.
IV
PAH

566
Q

Treprostinil

A

Tyvaso
IV, sc, PO, inhalation
PAH

567
Q

Iloprost

A

Ventavis.
Inhalation
PAH
Dilated pulmonary arteries and prevent blood clots

568
Q

Sildenafil

A

Ravatio

PAH

569
Q

Tadalafil

A

Adcirca

PAH

570
Q

Hydroxyzine

A

Vistaril

Anti histamine

571
Q

Fexofenadine

A

Allegra

2nd gen antihistamine

572
Q

Loratadine

A

Claritin, Alavert

2nd gen antihistamine

573
Q

Desloratadine

A

Clarinex

2nd gen antihistamine

574
Q

Cetirizine

A

Zyrtec

2nd gen antihistamine

575
Q

Levocetirizine

A

Xyzal

2nd gen antihistamine

576
Q

Ofirmev.

A

Acetaminophen IV

577
Q

Caldolor

A

Ibuprofen IV

Top drugs (3 decks)

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