Top ALS Meds Flashcards
metoprolol (Lopresor)
Classification: Beta Blocker, Antihypertensive
Mechanism of Action: Blocks Beta 1 receptors decreasing BP and HR
Normal recommended adult dose: 25-100 mg/day PO, two divided doses
Side effects: Erectile Dysfunction, fatigue, weakness, blurred vision
Nursing considerations: Monitor BP, Pulse and EKG, Daily weights, HF
lisinopril
Classification: Ace inhibitor, antihypertensive
Mechanism of Action: Block conversion of angiotensin 1 to angiotensin to preventing vasoconstriction; increase plasma renin levels and decrease aldosterone levels
Normal recommended adult dose: 10 mg/day, up to 20-40 mg/day
Side effects: Hypotension, dizziness, cough, edema
Nursing considerations: Monitor Pulse, BP, angioedema, daily weight, BUN, Creatinine, Potassium, Sodium
amlodipine
Classification: Calcium Channel Blockers, Antihypertensive
Mechanism of Action: INhibits transport of calcium into myocardial and vascular smooth muscle, inhibiting contraction
Normal recommended adult dose: 5-10 mg/day
Side effects: Peripheral Edema, dizziness, nausea, flushing, hypotension
Nursing considerations: Monitor Pulse, BP, daily weight, angina
enoxaparin (Lovenox)
Classification: Antithrombotics, Anticoagulants
Mechanism of Action: Inhibits effects on antithrombin on Factor Xa and thrombin, preventing clots
Normal recommended adult dose: 1 mg/kg BID
Side effects: bleeding, anemia
Nursing considerations: Monitor for bleeding or hemorrhage, CBC, Platelets, increase AST, ALT levels, watch for occult blood
furosemide (Lasix)
Classification: Loop Diuretic
Mechanism of Action: Inhibits reabsorption of sodium and chloride from the loop of Henle and distal tubule of the kidney
Normal recommended adult dose: 20-80 mg/day
Side effects: Dehydration, hypocalcemia, hypochloremia, hypovolemia, hyponatremia, hypomagnesemia, metabolic acidosis, aplastic anemia, stevens johnson syndrome
Nursing considerations: Monitor fluids, electrolytes, daily weight, edema, lung sounds, skin turgor, mucous membranes, BP and Pulse before administering, monitor for rash
diltiazem (Tiazac XR)
Classification: Calcium Channel Blockers, Antianginal, Antiarrhythmic
Mechanism of Action: Inhibits transport of calcium into myocardial and vascular smooth muscle cells, resulting in vasodilation, decreasing BP
Normal recommended adult dose: 30-100 mg/3-4x day; 180-240 mg/day XR
Side effects: Peripheral edema, bradycardia, arrhythmias, HF
Nursing considerations: Monitor BP/Pulse before giving, daily weight, assess for rash associated with Stevens Johnson Syndrome, Monitor EKG for arrhythmias.
Docusate Sodium
Classification: Stool Softeners
Mechanism of Action: Draws water into stool, softening it. May also bring electrolytes and water into the colon.
Normal recommended adult dose: 240 mg/day
Side effects: Cramps, diarrhea
Nursing considerations: Not a stimulant laxative, administered with water/juice but may be given on an empty stomach for rapid results.
Ondansetron(Zofran)
Classification: Five ht3 antagonists, Antiemetic
Mechanism of Action: Blocks effects of serotonin at 5HT3 receptor sites in the CNS
Normal recommended adult dose: 8-24 mg/8hr
Side effects: Constipation, diarrhea, headache serotonin syndrome, stevens johnson syndrome, toxic epidermal necrolysis
Nursing considerations: Assess for N/V, bowel sounds, distention before administering, monitor for serotonin syndrome, monitor for rash, may cause increased bilirubin, AST and ALT
ketorolac (Toradol)
Classification: Non-opioid analgesic
Mechanism of Action: Inhibits prostaglandin synthesis, antipyretic and antiinflammatory properties
Normal recommended adult dose: PO 20 mg initially, followed by 10mg/4-6hr
Side effects: GI bleeding, drowsiness, HF, Heart Attack, Stroke, rash, asthma
Nursing considerations: Assess for rash, monitor BP, assess pain before and after administration, may increase AST and ALT, prolonged bleeding time for 24-48 hrs, may increase BUN, Creatinine and K+
Metformin
Classification: Biguanide, Antidiabetic
Mechanism of Action: Decreases hepatic glucose production and intestinal glucose absorption, increases sensitivity to insulin
Normal recommended adult dose: 500 mg/BID mac 2000 mg/day in 3 divided doses
Side effects: Lactic acidosis, bloating, diarrhea, N/V
Nursing considerations: Monitor for hypoglycemia when taken with sulfonylureas, assess renal function before and during therapy, monitor folic acid and b12 in LT therapy
Morphine Sulfate
Classification: Opioid Agonists, Opioid analgesics
Mechanism of Action: Binds to opiate receptors in CNS
Normal recommended adult dose: PO 30 mg/3-4hr; IV 4-10mg/3-4hr
Side effects: Hypotension, constipation, N/V, sedation, confusion, dependance, respiratory depression.
Nursing considerations: Pain assessments, boluses for breakthrough pain, assess LOC, BP Pulse and RR before/after administration, monitor for abuse, may cause OD
Methylprednisolone (SOLU-Medrol)
Classification: Corticosteroids, antiinflammatory steroids, immunosuppressants
Mechanism of Action: Suppresses inflammation and normal immune response,
Normal recommended adult dose: PO 160 mg/day for 7 days, then 64 mg/every other day for 1 mo.
Side effects: HTN, acne, decreased wound healing, fragility, petechiae, hirsutism, ecchymosis, adrenal suppression, peptic ulcers, anorexia, N/V, muscle wasting, osteoporosis, depression, euphoria, cushingoid appearance
Nursing considerations: Monitor daily weight, BG, electrolytes, may suppress allergy testing, monitor for adrenal insufficiency
Allopurinol
Classification: Xanthine Oxidase Inhibitors, Antigout agents
Mechanism of Action: Inhibits the production of uric acid by inhibiting the action of xanthine oxidase
Normal recommended adult dose: 100 mg/day initially, 100-200 mg/2-3x daily maintenance dose
Side effects: Hypersensitivity, rash.
Nursing considerations: I&O, daily weight, S/S of DRESS, may cause hypoglycemia in those taking antidiabetics, monitor renal and liver function tests.
Fluticasone & Salmeterol (Advair)
Classification: Corticosteroids, Anti-inflammatories; Adrenergics, Bronchodilators
Mechanism of Action: Locally acting anti-inflammatory; Produces accumulation of cAMP at beta 2 receptors causing bronchodilation
Normal recommended adult dose: 88 mcg/BID max 880 mcg/day; 50 mcg BID
Side effects: Headache, hypersensitivity
Nursing considerations: Monitor for adrenal insufficiency, Monitor lung sounds, pulse, BP before administering, may increase BG
tamsulosin (Flomax)
Classification: Peripherally acting antiadrenergics
Mechanism of Action: Decreases contractions in smooth muscle by binding to alpha 1 receptors decreasing urinary urgency/nocturia
Normal recommended adult dose: 0.4mg/day
Side effects: Dizziness, headache
Nursing considerations: Take after a meal, daily weight.
insulin lispro (HumaLOG)
Classification: Hormone
Mechanism of Action: Stimulates glucose uptake in skeletal muscle/fat, inhibits hepatic glucose production to control hyperglycemia
Normal recommended adult dose: 0.5-1.2 units/kg/day
Onset: <15mins
Peak: 1-2hr
Duration: 3-4hrs
Side effects: Hypoglycemia, hypersensitivity
Nursing considerations: Assess blood glucose, HA1C, K+ levels, give when tray is in front of patient(rapid acting)
insulin aspart (NovoLOG)
Classification: Hormone
Mechanism of Action: Stimulates glucose uptake, inhibits hepatic glucose production
Normal recommended adult dose: 0.5-1 unit/kg/day
Onset: <15 mins
Peak: 1-2 hr
Duration: 3-4 hr
Side effects: Hypoglycemia, anaphylaxis
Nursing considerations: Assess blood glucose, hypoglycemia
insulin regular (Entuzity)
Classification: Hormone
Mechanism of Action: Stimulate glucose uptake, inhibits, hepatic glucose production
Normal recommended adult dose: 0.5-1 unit/kg/day
Onset: 30-60 mins
Peak: 2-4hr
Duration: 5-7 hr
Side effects: Hypoglycemia
Nursing considerations: Monitor weight, BG, hypoglycemia, only one that can be given IV
insulin glargine
Classification: Hormone
Mechanism of Action: Stimulates glucose uptake, inhibits hepatic glucose production
Normal recommended adult dose: ⅓ of total daily insulin given
Onset: 3-4hr
Peak: None
Duration: 24hr
Side effects: Hypoglycemia
Nursing considerations: Long lasting insulin
heparin (sub Q)
Classification: Anticoagulants
Mechanism of Action: Inhibits antithrombin to effect on thrombin and factor Xa, prevents conversion of prothrombin to thrombin in low doses, high doses neutralize thrombin which prevents conversion of fibrinogen to fibrin
Normal recommended adult dose: 5,000-10,000 units/ 4-6 hr
Side effects: Anemia, bleeding, HIT
Nursing considerations: Monitor for bleeding and hemorrhage, platelets, may increase ALT/AST