Top ALS Meds Flashcards

1
Q

metoprolol (Lopresor)

A

Classification: Beta Blocker, Antihypertensive
Mechanism of Action: Blocks Beta 1 receptors decreasing BP and HR
Normal recommended adult dose: 25-100 mg/day PO, two divided doses
Side effects: Erectile Dysfunction, fatigue, weakness, blurred vision
Nursing considerations: Monitor BP, Pulse and EKG, Daily weights, HF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

lisinopril

A

Classification: Ace inhibitor, antihypertensive
Mechanism of Action: Block conversion of angiotensin 1 to angiotensin to preventing vasoconstriction; increase plasma renin levels and decrease aldosterone levels
Normal recommended adult dose: 10 mg/day, up to 20-40 mg/day
Side effects: Hypotension, dizziness, cough, edema
Nursing considerations: Monitor Pulse, BP, angioedema, daily weight, BUN, Creatinine, Potassium, Sodium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

amlodipine

A

Classification: Calcium Channel Blockers, Antihypertensive
Mechanism of Action: INhibits transport of calcium into myocardial and vascular smooth muscle, inhibiting contraction
Normal recommended adult dose: 5-10 mg/day
Side effects: Peripheral Edema, dizziness, nausea, flushing, hypotension
Nursing considerations: Monitor Pulse, BP, daily weight, angina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

enoxaparin (Lovenox)

A

Classification: Antithrombotics, Anticoagulants
Mechanism of Action: Inhibits effects on antithrombin on Factor Xa and thrombin, preventing clots
Normal recommended adult dose: 1 mg/kg BID
Side effects: bleeding, anemia
Nursing considerations: Monitor for bleeding or hemorrhage, CBC, Platelets, increase AST, ALT levels, watch for occult blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

furosemide (Lasix)

A

Classification: Loop Diuretic
Mechanism of Action: Inhibits reabsorption of sodium and chloride from the loop of Henle and distal tubule of the kidney
Normal recommended adult dose: 20-80 mg/day
Side effects: Dehydration, hypocalcemia, hypochloremia, hypovolemia, hyponatremia, hypomagnesemia, metabolic acidosis, aplastic anemia, stevens johnson syndrome
Nursing considerations: Monitor fluids, electrolytes, daily weight, edema, lung sounds, skin turgor, mucous membranes, BP and Pulse before administering, monitor for rash

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

diltiazem (Tiazac XR)

A

Classification: Calcium Channel Blockers, Antianginal, Antiarrhythmic
Mechanism of Action: Inhibits transport of calcium into myocardial and vascular smooth muscle cells, resulting in vasodilation, decreasing BP
Normal recommended adult dose: 30-100 mg/3-4x day; 180-240 mg/day XR
Side effects: Peripheral edema, bradycardia, arrhythmias, HF
Nursing considerations: Monitor BP/Pulse before giving, daily weight, assess for rash associated with Stevens Johnson Syndrome, Monitor EKG for arrhythmias.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Docusate Sodium

A

Classification: Stool Softeners
Mechanism of Action: Draws water into stool, softening it. May also bring electrolytes and water into the colon.
Normal recommended adult dose: 240 mg/day
Side effects: Cramps, diarrhea
Nursing considerations: Not a stimulant laxative, administered with water/juice but may be given on an empty stomach for rapid results.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ondansetron(Zofran)

A

Classification: Five ht3 antagonists, Antiemetic
Mechanism of Action: Blocks effects of serotonin at 5HT3 receptor sites in the CNS
Normal recommended adult dose: 8-24 mg/8hr
Side effects: Constipation, diarrhea, headache serotonin syndrome, stevens johnson syndrome, toxic epidermal necrolysis
Nursing considerations: Assess for N/V, bowel sounds, distention before administering, monitor for serotonin syndrome, monitor for rash, may cause increased bilirubin, AST and ALT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

ketorolac (Toradol)

A

Classification: Non-opioid analgesic
Mechanism of Action: Inhibits prostaglandin synthesis, antipyretic and antiinflammatory properties
Normal recommended adult dose: PO 20 mg initially, followed by 10mg/4-6hr
Side effects: GI bleeding, drowsiness, HF, Heart Attack, Stroke, rash, asthma
Nursing considerations: Assess for rash, monitor BP, assess pain before and after administration, may increase AST and ALT, prolonged bleeding time for 24-48 hrs, may increase BUN, Creatinine and K+

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Metformin

A

Classification: Biguanide, Antidiabetic
Mechanism of Action: Decreases hepatic glucose production and intestinal glucose absorption, increases sensitivity to insulin
Normal recommended adult dose: 500 mg/BID mac 2000 mg/day in 3 divided doses
Side effects: Lactic acidosis, bloating, diarrhea, N/V
Nursing considerations: Monitor for hypoglycemia when taken with sulfonylureas, assess renal function before and during therapy, monitor folic acid and b12 in LT therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Morphine Sulfate

A

Classification: Opioid Agonists, Opioid analgesics
Mechanism of Action: Binds to opiate receptors in CNS
Normal recommended adult dose: PO 30 mg/3-4hr; IV 4-10mg/3-4hr
Side effects: Hypotension, constipation, N/V, sedation, confusion, dependance, respiratory depression.
Nursing considerations: Pain assessments, boluses for breakthrough pain, assess LOC, BP Pulse and RR before/after administration, monitor for abuse, may cause OD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Methylprednisolone (SOLU-Medrol)

A

Classification: Corticosteroids, antiinflammatory steroids, immunosuppressants
Mechanism of Action: Suppresses inflammation and normal immune response,
Normal recommended adult dose: PO 160 mg/day for 7 days, then 64 mg/every other day for 1 mo.
Side effects: HTN, acne, decreased wound healing, fragility, petechiae, hirsutism, ecchymosis, adrenal suppression, peptic ulcers, anorexia, N/V, muscle wasting, osteoporosis, depression, euphoria, cushingoid appearance
Nursing considerations: Monitor daily weight, BG, electrolytes, may suppress allergy testing, monitor for adrenal insufficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Allopurinol

A

Classification: Xanthine Oxidase Inhibitors, Antigout agents
Mechanism of Action: Inhibits the production of uric acid by inhibiting the action of xanthine oxidase
Normal recommended adult dose: 100 mg/day initially, 100-200 mg/2-3x daily maintenance dose
Side effects: Hypersensitivity, rash.
Nursing considerations: I&O, daily weight, S/S of DRESS, may cause hypoglycemia in those taking antidiabetics, monitor renal and liver function tests.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Fluticasone & Salmeterol (Advair)

A

Classification: Corticosteroids, Anti-inflammatories; Adrenergics, Bronchodilators
Mechanism of Action: Locally acting anti-inflammatory; Produces accumulation of cAMP at beta 2 receptors causing bronchodilation
Normal recommended adult dose: 88 mcg/BID max 880 mcg/day; 50 mcg BID
Side effects: Headache, hypersensitivity
Nursing considerations: Monitor for adrenal insufficiency, Monitor lung sounds, pulse, BP before administering, may increase BG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

tamsulosin (Flomax)

A

Classification: Peripherally acting antiadrenergics
Mechanism of Action: Decreases contractions in smooth muscle by binding to alpha 1 receptors decreasing urinary urgency/nocturia
Normal recommended adult dose: 0.4mg/day
Side effects: Dizziness, headache
Nursing considerations: Take after a meal, daily weight.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

insulin lispro (HumaLOG)

A

Classification: Hormone
Mechanism of Action: Stimulates glucose uptake in skeletal muscle/fat, inhibits hepatic glucose production to control hyperglycemia
Normal recommended adult dose: 0.5-1.2 units/kg/day
Onset: <15mins
Peak: 1-2hr
Duration: 3-4hrs
Side effects: Hypoglycemia, hypersensitivity
Nursing considerations: Assess blood glucose, HA1C, K+ levels, give when tray is in front of patient(rapid acting)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

insulin aspart (NovoLOG)

A

Classification: Hormone
Mechanism of Action: Stimulates glucose uptake, inhibits hepatic glucose production
Normal recommended adult dose: 0.5-1 unit/kg/day
Onset: <15 mins
Peak: 1-2 hr
Duration: 3-4 hr
Side effects: Hypoglycemia, anaphylaxis
Nursing considerations: Assess blood glucose, hypoglycemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

insulin regular (Entuzity)

A

Classification: Hormone
Mechanism of Action: Stimulate glucose uptake, inhibits, hepatic glucose production
Normal recommended adult dose: 0.5-1 unit/kg/day
Onset: 30-60 mins
Peak: 2-4hr
Duration: 5-7 hr
Side effects: Hypoglycemia
Nursing considerations: Monitor weight, BG, hypoglycemia, only one that can be given IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

insulin glargine

A

Classification: Hormone
Mechanism of Action: Stimulates glucose uptake, inhibits hepatic glucose production
Normal recommended adult dose: ⅓ of total daily insulin given
Onset: 3-4hr
Peak: None
Duration: 24hr
Side effects: Hypoglycemia
Nursing considerations: Long lasting insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

heparin (sub Q)

A

Classification: Anticoagulants
Mechanism of Action: Inhibits antithrombin to effect on thrombin and factor Xa, prevents conversion of prothrombin to thrombin in low doses, high doses neutralize thrombin which prevents conversion of fibrinogen to fibrin
Normal recommended adult dose: 5,000-10,000 units/ 4-6 hr
Side effects: Anemia, bleeding, HIT
Nursing considerations: Monitor for bleeding and hemorrhage, platelets, may increase ALT/AST

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

warfarin

A

Classification: Coumarins, Anticoagulants
Mechanism of Action: Interferes with hepatic synthesis of vit K dependant clotting factors (2, 7, 9, 10)
Normal recommended adult dose: 2-5 mg/day for 2-4 days then adjust based on INR
Side effects: Bleeding, calciphylaxis
Nursing considerations: Monitor for bleeding and hemorrhage, PT, INR

22
Q

Albuterol & Ipratropium

A

Classification: Adrenergics, Bronchodilators; Anticholinergics, Bronchodilators
Mechanism of Action: Binds to beta 2 receptors in smooth muscle; inhibits cholinergic receptors in bronchial smooth muscle causing bronchodilation
Normal recommended adult dose: 100mcg-20mcg inhalation as needed
Side effects: Chest pain, nervousness, restlessness, tremors, palpitations, bronchospasm
Nursing considerations: Assess lung sounds, pulse, BP, RR before administration, observe for wheezing, may decrease potassium levels

23
Q

sertraline (Zoloft)

A

Classification: SSRIs, Antidepressants
Mechanism of Action: Inhibits neuronal uptake of serotonin in CNS
Normal recommended adult dose: 50 mg/day; 200 mg/day max
Side effects: Increased sweating, diarrhea, dry mouth, nausea, tremors, dizziness, suicidal thoughts, fatigue, headache, insomnia, serotonin syndrome
Nursing considerations: Monitor for suicidal ideation, serotonin syndrome, appetite, may cause hyperglycemia

24
Q

oxycodone (Supeudol)

A

Classification: Opioid agonists, Opioid analgesics
Mechanism of Action: Binds to opiate receptors in the CNS
Normal recommended adult dose: 5-10 mg/3-4 hr PRN
Side effects: Constipation, confusion, sedation, respiratory depression, dependance, dry mouth, sweating
Nursing considerations: Pain assessments, Assess BP, pulse, RR before/after administration, monitor for dependance, may cause OD

25
Q

omeprazole (Losec)

A

Classification: Proton Pump Inhibitors, Antiulcer agents
Mechanism of Action: Binds to enzymes in presence of gastric acid preventing hydrogen atoms from entering the gastric lumen, resulting in less acid in the stomach
Normal recommended adult dose: 20 mg/day
Side effects: C-diff, abdominal pain, hypersensitivity
Nursing considerations: Monitor bowel function, assess for pain and occult blood, may increase AST/ALT

26
Q

diphenhydramine (Benadryl)

A

Classification: Antihistamines
Mechanism of Action: Antagonizes effects of histamine at H1 receptor sites
Normal recommended adult dose: 25-50 mg/4-6hr; 300 mg/day max
Side effects: Anorexia, dry mouth, dizziness, drowsiness
Nursing considerations: Assess sleep, may decrease skin response to allergy tests, discontinue 4 days before testing

27
Q

potassium chloride (Micro-K)

A

Classification: Mineral and electrolyte supplements
Mechanism of Action: Maintain acid-base balance, isotonicity and electrolyte balance in the cells
Normal recommended adult dose: 40-100 mEq/day in divided doses
Side effects: Arrhythmias, abdominal pain, diarrhea, flatulence, N/V
Nursing considerations: Assess for hypokalemia, monitor serum potassium

28
Q

glipizide (Glucotrol)

A

Classification: Sulfonylureas, Antidiabetics
Mechanism of Action: Stimulate pancreatic insulin release, increase sensitivity to insulin
Normal recommended adult dose: 2.5-40 mg/day
Side effects: Photosensitivity, hypoglycemia, aplastic anemia
Nursing considerations: Monitor for hypoglycemia, monitor CBC, may increase AST, LDH, BUN, Creatinine, Monitor BG and HA1C

29
Q

Culturelle (Lactobacillus)

A

Classification: Probiotic
Mechanism of Action: Produces lactic acid preventing survival of harmful bacteria in the GI tract
Normal recommended adult dose: 15 billion cell/day
Side effects: Bloating, gas, yeast infections, nausea
Nursing considerations: Assess for yeast infections, not to be used in people with weak immune systems or short-gut syndrome

30
Q

vancomycin (Vancocin)

A

Classification: Anti Infectives
Mechanism of Action: Binds to bacterial cell wall, resulting in cell death
Normal recommended adult dose: IV 500 mg/6hr; max 4 g/day
Side effects: Rash, nephrotoxicity, phlebitis, pain, hypersensitivity
Nursing considerations: Assess S/S of infection, obtain cultures, monitor IV site, monitor BP, daily weight, Monitor for anaphylaxis, may decrease BUN

31
Q

levofloxacin

A

Classification: Fluroquinolones, Anti-infectives
Mechanism of Action: Inhibits bacterial DNA synthesis by inhibiting DNA gyrase enzymes
Normal recommended adult dose: IV 500-750 mg/day for 7-14 days
Side effects: Elevated ICP, seizures, suicidal thoughts, aortic aneurysm, torases de pointes, stevens johnson syndrome, hepatotoxicity, C-Diff, Nausea, hypersensitivity, phlebitis
Nursing considerations: Assess for infection, cultures, monitor bowels, assess for rash, assess for anaphylaxis, monitor for suicidal thoughts

32
Q

acetylsalicylic acid (Aspirin/ASA)

A

Classification: Salicylates, Antiplatelets, nonopioid analgesics
Mechanism of Action: Inhibits production of prostaglandins, decreases platelet aggregation
Normal recommended adult dose: 81-325 mg/4-6 hr; 4 g/day max
Side effects: GI bleeding, dyspepsia, epigastric distress, nausea, hypersensitivity
Nursing considerations: Monitor for DRESS, assess pain, assess for hypersensitivity, monitor hepatic function, prolongs bleeding time for 4-7 days and can cause prolonged prothrombin time in large doses, monitor hematocrit in prolonged high doses.

33
Q

clopidogrel (Plavix)

A

Classification: Platelet aggregation inhibitors, Antiplatelet agents
Mechanism of Action: Inhibits platelet aggregation by inhibiting binding of ATP to platelet receptors
Normal recommended adult dose: 75 mg/day
Side effects: Rash, GI Bleeding, Neutropenia, hypersensitivity, stevens johnson syndrome
Nursing considerations: monitor bleeding time, CBC with differential and platelet count, may increase bilirubin, hepatic enzymes, cholesterol, and uric acid

34
Q

hydrochlorothiazide (Urozide)

A

Classification: Thiazide Diuretics, Antihypertensives
Mechanism of Action: Increases excretion of Na and Water by inhibiting sodium reabsorption in the distal tubule, lowering BP
Normal recommended adult dose: 12.5-100 mg.day in 1-2 doses; 200 mg/day max(50 mg/day max for HTN)
Side effects: Skin cancer, stevens johnson syndrome, hypokalemia, pancreatitis
Nursing considerations: Monitor BP, Daily weight, assess for edema, assess for rash, monitor electrolytes, BIN, BG, Creatinine and uric acid levels

35
Q

fluoxetine (Prozac)

A

Classification: SSRIs, Antidepressants
Mechanism of Action: Selectively inhibits the reuptake of serotonin in the CNS
Normal recommended adult dose: 10-50 mg/day; max 80 mg/day
Side effects: Torsades de pointes, increased sweating, pruritus, diarrhea, tremors, seizures, suicidal thoughts, anxiety drowsiness, headache, insomnia, nervousness, serotonin syndrome
Nursing considerations: Monitor for mood changes, suicidal thoughts, monitor appetite, serotonin syndrome, monitor CBC with differential, may increase ALT, BUN, may cause hypoglycemia in those with diabetes

36
Q

tramadol (Trideral)

A

Classification: Centrally acting opioid analgesics
Mechanism of Action: Binds to opioid receptors, inhibits reuptake of serotonin and norepinephrine in the CNS
Normal recommended adult dose: 50-100 mg/4-6hr; 400 mg/day max
Side effects: Constipation, Nausea, Seizures, dizziness, headache, somnolence, respiratory depression
Nursing considerations: Schedule 4 controlled substance, Assess pain, Monitor BP, RR before/after administration, assess bowel function, monitor for dependance

37
Q

hydrocodone (Vicodin)

A

Classification: Opioid agonists nonopioid analgesic combinations, Opioid analgesics
Mechanism of Action: Binds to opiate receptors in the CNS, suppress the cough reflex via central action
Normal recommended adult dose: 2.5-10 mg/3-6 hr PRN
Side effects: Hypotension, constipation, dyspepsia, nausea, confusion, dizziness, sedation, respiratory depression, dependance
Nursing considerations: Assess BP, pulse, RR before/after administration, monitor for dependance, monitor for respiratory depression, pain assessments, may cause OD

38
Q

lorazepam (Ativan)

A

Classification: Benzodiazepines, Anti Anxiety agents, sedatives/hypnotics
Mechanism of Action: Depressed the CNS by potentiating GABA
Normal recommended adult dose: 1-3 mg/2-3x daily; max 10 mg/day
Side effects: Dizziness, drowsiness, respiratory depression, dependence, lethargy
Nursing considerations: Assess for risk of abuse or dependance

39
Q

piperacillin/tazobactam (Zosyn)

A

Classification: Extended spectrum penicillins, Anti infectives
Mechanism of Action: Binds to cell wall membrane causing cell death; inhibits beta-lactamase, and enzyme that can destroy penicillins
Normal recommended adult dose: 4.5 g/6hr IV
Side effects: SJS, Rash, C-Diff, Pain, Phlebitis, seizures, hypersensitivity
Nursing considerations: Assess for infection, cultures, observe for anaphylaxis, monitor bowel function, assess skin, monitor for DRESS, CBC

40
Q

nitroglycerin (Nitroject)

A

Classification: Nitrates, Antianginals
Mechanism of Action: Increases coronary blood flow by dilating coronary arteries, produces vasodilation, decreases left ventricular diastolic pressure and preload, reduces myocardial oxygen consumption
Normal recommended adult dose: 0.3-0/6 mg may repeat every 5 mins for 2 additional doses in acute anginal attack
Side effects: Hypotension, tachycardia, dizziness, headache
Nursing considerations: Pain assessment, monitor BP and Pulse before administration, sit down next to phone during administration

41
Q

nystatin (Nyaderm)

A

Classification: Antifungals
Mechanism of Action: Affects permeability of fungal cell wall, allowing lysis
Normal recommended adult dose: Apply cream, ointment or powder 2-3 times daily until healing is complete, PO 400,000-600,000 units/4x daily as suspension
Side effects: Burning, itching, redness; PO nausea, diarrhea, pain, vomiting
Nursing considerations: Assess skin and mucous membranes before application

42
Q

ibuprofen (Motrin, Advil)

A

Classification: NSAIDs, nonopioid analgesics
Mechanism of Action: Inhibits prostaglandin synthesis
Normal recommended adult dose: 200-800 mg/4-6hr; 3200 mg/day max
Side effects: HF, MI, Stroke, Stevens Johnson Syndrome, GI Bleeding, Hepatitis, constipation, dyspepsia, nausea, vomiting, headache, hypersensitivity, renal failure
Nursing considerations: Assess for GI Bleeding, Rash, Monitor for DRESS, assess pain, BUN, Creatinine, CBC and liver test should be evaluated in long term therapy

43
Q

Polyethylene glycol (MiraLax)

A

Classification: Osmotics, Laxatives
Mechanism of Action: Draws water into the lumen of the GI tract
Normal recommended adult dose: 17g(1 TBS) in 8oz of water daily, use up to 2 weeks
Side effects: Cramping, pain, flatulence
Nursing considerations: Assess bowel sounds, distention, pain, assess stool produced, assess usual bowel patterns

44
Q

scopolamine

A

Classification: Anticholinergics, Antiemetics
Mechanism of Action: Inhibits muscarinic activity of acetylcholine, corrects imbalance of acetylcholine and norepinephrine in the CNS
Normal recommended adult dose: Apply 1 patch 4hr prior to travel and every 3 days PRN
Side effects: Tachycardia, blurred vision, dry mouth, urinary hesitancy, drowsiness, decreased sweating
Nursing considerations: Assess for anticholinergic symptoms (“Can’t see, can’t spit, can’t pee, can’t shit”)

45
Q

spironolactone

A

Classification: Potassium Sparing Diuretics
Mechanism of Action: Loss of Sod. Bicarb and Ca while sparing K and Hydrogen ions by antagonizing aldosterone, inhibits testosterone secretion and androgen binding to their receptors
Normal recommended adult dose: 25100 mg/day
Side effects: Hyperkalemia, dizziness, muscle cramps, DRESS, hypersensitivity
Nursing considerations: Daily weight, BP, ECG’s, Monitor for hyperkalemia

46
Q

valsartan (Diovan)

A

Classification: Angiotensin 2 receptor antagonists, Antihypertensives
Mechanism of Action: Blocks the vasoconstrictor and aldosterone secreting effects of angiotensin 2, including vascular smooth muscle and adrenal glands
Normal recommended adult dose: 80 or 160 mg/day; max 320 mg
Side effects: Dizziness, edema, diarrhea, angioedema
Nursing considerations: Monitor BP, monitor for angioedema, daily weight

47
Q

hydromorphone (Dilaudid)

A

Classification: Opioid agonist, Opioid analgesics
Mechanism of Action: Binds to opioid receptors in the CNS
Normal recommended adult dose: PO 4-8 mg/3-4hr
Side effects: Hypotension, Constipation, confusion, sedation, respiratory depression, dependance
Nursing considerations: Assess BP, pulse, RR before/after administration, monitor for respiratory depression, monitor for dependence, pain assessment, may cause OD

48
Q

simvastatin

A

Classification: hmg coa reductase inhibitors (statin), Lipid-lowering agents
Mechanism of Action: Inhibits HMG-CoA reductase, an enzyme partly responsible for the synthesis of cholesterol
Normal recommended adult dose: 5-40 mg/day in the evening
Side effects: Rash, abdominal cramps, constipation, diarrhea, flatus, heartburn, rhabdomyolysis, hypersensitivity
Nursing considerations: Night med, Obtain diet history, evaluate cholesterol and triglyceride levels before/during therapy

49
Q

levothyroxine (Eltroxin)

A

Classification: Hormones
Mechanism of Action: Synthetic form of thyroxine (T4), replacement thyroid hormones
Normal recommended adult dose: 1.6 mcg/day
Side effects: Headache, diarrhea, hyperthyroidism, arrhythmias, tachycardia
Nursing considerations: Apical Pulse and BP prior to administration, monitor height, weight and motor development in children

50
Q

cephalexin (Keflex)

A

Classification: First Generation Cephalosporins, Anti Infectives
Mechanism of Action: Binds to bacterial cell membrane, causing cell death
Normal recommended adult dose: 200-500 mg/6hr; max 4 g/day
Side effects: Diarrhea, seizures in high doses, ,C-Diff,
Nursing considerations: Assess for S/S of infection, cultures, observe for anaphylaxis, monitor bowel function, may increase AST, ALT, Bilirubin, LDH, BUN, Creatinine

51
Q

metronidazole (Flagyl)

A

Classification: Anti Infectives, antiulcer agents
Mechanism of Action: Disrupts DNA and protein synthesis in susceptible organisms
Normal recommended adult dose: 7.5 mg/kg/6hr; max 4 g/day
Side effects: Stevens Johnson Syndrome, abdominal pain, anorexia, nausea, seizures, dizziness, headache, aseptic meningitis,
Nursing considerations: Assess for infection, cultures, monitor neuro status, daily weight, assess for rash (SJS)

52
Q

acetaminophen (Tylenol)

A

Classification: Antipyretic, nonopioid analgesic
Mechanism of Action: Inhibits prostaglandin synthesis
Normal recommended adult dose: 325-650 mg/6hr; max 3000 mg/day or 2000 mg/day in those with hepatic or renal impairment
Side effects: Hepatotoxicity, SJS, renal failure
Nursing considerations: Hepatotoxicity risk, assess for rash, assess pain, assess fever, watch for increased bilirubin, LDH, AST, ALT and prothrombin time may indicate hepatotoxicity, acetylcysteine is the antidote for OD