Top 300 indications

Question 1

Acyclovir indications and dosing

Answer 1

1.) Genital herpes simplex:
Adults, initial episode-
400 mg TID x7-10 days
200 mg PO 5x daily x 7-10 days
Adults, recurrent-
400 mg TID x 5 days
800 mg BID x 5 days
800 mg TID x 2 days

2.) Genital herpes simplex, suppressive therapy:
Adults and children >/= 12 years old: 400 mg BID for up to 12 months

3.) Herpes zoster (shingles):
Adults and children >/= 12 years old: 800 mg 5x daily for 7-10 days

4.) Varicella (chickenpox):
Adults- 800 mg po 5 x daily x 5-7 days

5.) Cold sores (orolabial HSV treatment): 400 mg PO TID x 5-10 days

Question 2

Adapalene indications and dosing

Answer 2

1.) Acne vulgaris:
Adults and children >12 yo, apply thin film topically to affected area(s) daily hs

Question 3

Albendazole indications and dosing

Answer 3

1.) Parenchymal neurocysticercosis caused by Taenia solium, cystic hydatid disease of the liver, lung, and peritoneum caused by Echinococcus granulosus:
Adults >/= 60 kg- 400 mg PO BID with meals x 8-30 days
Adults and children <60 kg: 15mg/kg/day (max 800mg/day) in 2 divided doses x 8-30 days

Question 4

Albuterol indications and dosing

Answer 4

1.) Asthma (acute exacerbation):
Adults, MDI, 4-8 inhalations every 20 min up to 4 h, then every 1-4 h prn
Children, 4-8 inhalations every 20 min for 3 doses, then every 1-4 h prn (use mask for children <4 y of age)

2.)Asthma (bronchospasm):
Adults and Children, MDI/dry powder inhalation, 2 inhalations every 4-6 h prn
Adults and Children ≥12 y of age, oral, 2-4 mg immediate-release tablet po tid or qid or 4-8 mg extended release tablet po q12h (max 32 mg/d)

3.) Exercise-induced asthma, prevention:
Adults, MDI/dry powder inhalation, 2 inhalations 15-30 min prior to exercise

4.) Chronic obstructive pulmonary disease (acute symptom relief): MDI/dry powder inhalation, 2 inhalations every 4-6 h prn

5.) Chronic obstructive pulmonary disease (acute exacerbation): MDI/dry powder inhalation, 1-8 inhalations every 1-4 h prn

Question 5

Alendronate indications and dosing

Answer 5

1.) Postmenopausal osteoporosis, prophylaxis: 5 mg po daily or 35 mg po once weekly
2.) Postmenopausal osteoporosis, treatment: 10 mg po daily or 70 mg po once weekly
3.) Osteoporosis, treatment, male: 10 mg once daily or 70 mg po once weekly
4.) Glucocorticoid-induced osteoporosis in those with daily dosage ≥7.5 mg of prednisone (or equivalent) treatment: 10 mg po once daily or 70 mg po once weekly
5.) Paget disease: 40 mg po daily for 6 mo
6.) Osteoporosis, prophylaxis, male: 5 mg po once daily or 35 mg po once weekly

Question 6

Allopurinol indications and dosing

Answer 6

1.) Gout, mild: 100-300 mg po daily; max dose 800 mg/d
2.) Gout, moderate to severe: 400-600 mg po daily in 2-3 divided doses, max dose 800 mg/d
3.) Hyperuricemia, tumor lysis syndrome: Children <6 y, 50 mg po tid or 150 mg po daily for 2-3 d; Children 6-10 y, 100 mg po tid or 300 mg po daily for 2-3 d; Adults, 600-800 mg/d po daily in 2-3 divided doses for 2-3 d; starting 12 h-3 d prior to chemotherapy
4.) Nephrolithiasis prophylaxis due to calcium stones: 300 mg/d divided in 1-3 doses

Question 7

Alprazolam indications and dosing

Answer 7

1.) Anxiety: immediate-release, orally disintegrating tablet or solution, 0.25-0.5 mg po tid; max daily dose, 4 mg in divided doses
2.) Panic disorder, with or without agoraphobia: immediate-release or orally disintegrating tablets, 0.5 mg po tid, extended release 3-6 mg po daily; dose may be increased every 3-4 d by <1 mg/d

Question 8

Amiodarone indications and dosing

Answer 8

Secondary prophylaxis of ventricular arrhythmias: 400 mg po q8-12h × 1-2 wk, then 200-400 mg po once daily or 400 mg po q8-24h for a total load of 6-10 g, then 200-400 mg po once daily

Question 9

Amitriptyline indications and dosing

Answer 9

Depression: Adults, 75 mg po divided into 1-3 daily doses, titrate to max 300 mg/d; Children ≥12 y of age, 10 mg po tid or 20 mg po daily hs

Question 10

Amlodipine indications and dosing

Answer 10

1.) HTN: Children 6-17 y of age, 2.5-5 mg po daily; Adults, 5-10 mg po daily
2.) Stable angina: 5-10 mg po daily
3.) Variant angina: 5-10 mg po daily

Question 11

Amoxicillin indications and dosing

Answer 11

1.) Acute otitis media: Adults, 500 mg q8h or 875 mg po q12h × 10 d; Children, 80-90 mg/kg/d po in 2-3 divided doses
2.) Lower respiratory tract infection: Adults, 1 g po tid × 10 d; Children, 45 mg/kg/d divided q12h
3.) Pharyngitis, tonsillitis: Adults and Children >12 y, 775 mg po daily × 10 d
4.) Streptococcal pharyngitis: Adults, 500 mg po bid or 1 g po daily × 10 d; Children, 50 mg/kg po once daily for 10 d, max 1 g daily
5.) Ear, nose, and throat infection, infection of skin and/or subcutaneous tissue, infection of genitourinary system: Adults, 500 mg po q8h or 875 mg po q12h × 5-10 d; Children, 25-45 mg/kg/d po divided q12h
6.) H. pylori GI tract infection: 1 g po bid with PPI

Question 12

Amoxicillin/clavulanate indications and dosing

Answer 12

1.) Acute otitis media: Adults, 500-875 mg po q12h × 10 d; Children, 80-90 mg/kg/d po in 2-3 divided doses
2.) Community-acquired pneumonia: Adults, 2000 mg extended release po bid or 500 mg po tid or 875 mg po bid × 5 d
3.) Lower respiratory tract infection: Adults, 1000 mg po tid × 10 d; Children, 45 mg/kg/d po divided q12h
4.) Sinusitis, infection of skin or subcutaneous tissue, infectious disease of genitourinary system: Adults, 500-875 mg po q8-12h or 2000 mg extended release po q12h × 5-7 d; Children, 25-45 mg/kg/d po divided q12h
5.) Urinary tract infection, acute cystitis: 500 mg po bid × 5-7 d
6.) Urinary tract infection, pyelonephritis: 875 mg po bid × 10-14 d

Question 13

Anastrazole indications and dosing

Answer 13

1.) Breast cancer, adjuvant, postmenopausal, hormone receptor-positive: 1 mg po daily × 5 y (or × 10 y when used in combination with tamoxifen)
2.) Breast cancer, advanced or metastatic, postmenopausal, following tamoxifen therapy: 1 mg po daily, until tumor progression

Question 14

Apixaban indications and dosing

Answer 14

1.) Atrial fibrillation, nonvalvular (prophylaxis, to reduce the risk of stroke): 5 mg po bid
2.) Hip or knee replacement surgery (prophylaxis, to reduce the risk of DVT and PE): 2.5 mg po bid × 12 d (knee replacement) or 35 d (hip replacement); start 12-24 h postoperatively
3.) DVT or PE (treatment and to reduce the future risk): 10 mg po bid × 7 d, then 5 mg po bid

Question 15

Aripiprazole indications and dosing

Answer 15

1.) Bipolar disorder, manic or mixed episodes, acute treatment: Adults, 10-15 mg po daily, may titrate to 15-30 mg po daily; Children >10 y, 2 mg po daily, may titrate to 10 mg po daily
2.) Schizophrenia: Adults, 10-15 mg po daily, may titrate to max 30 mg/d; Children >13 y, 2 mg po daily, may titrate to 10 mg po daily
3.) Depression, adjunctive with antidepressant: 2-4 mg po daily, may titrate to 15 mg po daily
4.) Tourette syndrome: Children ≥6 y of age and <50 kg, 2 mg po daily, may titrate to 5-10 mg po daily; Children ≥6 y of age and ≥50 kg, 2 mg po daily, may titrate to 10-20 mg po daily
5.) Irritability with autistic disorder: Children ≥6 y of age, 2 mg po daily × 7 d, then 5 mg po daily, may titrate to 15 mg/d

Question 16

Atazanavir indications and dosing

Answer 16

1.) Treatment of HIV-1 infection, antiretroviral-naïve: Adults and Children ≥13 y of age and ≥40 kg, 300 mg po daily with ritonavir 100 mg or cobicistat 150 mg; Adults unable to tolerate ritonavir, atazanavir 400 mg daily (ritonavir unboosted regimen not recommended in children)
2.) Treatment of HIV-1 infection, patients with prior virologic failure: Adults and Children ≥13 y of age and ≥40 kg, 300 mg po daily with ritonavir 100 mg or cobicistat (monotherapy with atazanavir not recommended); Children <13 y of age, weight based and used in combination with ritonavir
3.) Treatment of HIV-1 infection in pregnant patients, antiretroviral-naïve or experienced: 300 mg po daily with ritonavir 100 mg po daily

Question 17

Atenolol indications and dosing

Answer 17

1.) Angina pectoris, chronic: 50 mg po daily; titrate to 100-200 mg po daily
2.) HTN: Adults, 50 mg po daily, titrate to 100 mg po daily; Children, 0.5-1 mg/kg/d po in 1-2 divided doses, titrate to 2 mg/kg/d po in 1-2 divided doses (max 100 mg/d)
3.) AMI: 25-50 mg po bid (max 100 mg/d in 1-2 divided doses

Question 18

Atomoxetine indications and dosing

Answer 18

ADHD: Children >6 y of age and weighing ≤70 kg, 0.5 mg/kg/d po, may titrate to lower of 1.4 mg/kg/d or 100 mg/d; Children >6 y of age and weighing >70 kg, 40 mg/d po, may titrate to 100 mg/d; Adults, 40 mg po daily, may titrate to 100 mg/d

Question 19

Atorvastatin indications and dosing

Answer 19

1.) Hyperlipidemia: 10-20 mg po daily, may increase to 80 mg po daily
2.) Primary and secondary prevention of atherosclerotic cardiovascular disease: 10-20 mg po daily, may increase to 80 mg po daily for those patients requiring high-intensity therapy (eg, LDL >190 mg/dL or high ASCVD risk)
3.) Secondary prevention of cardiovascular events in patients with or at high risk for CAD: 80 mg daily, may reduce dose to 40 mg po daily if high dose not tolerated
4.) Familial hypercholesterolemia (homozygous): Children (boys and postmenarchal girls 10-17 y of age), 10 mg po daily, may titrate to 40 mg po daily; Adults, 10-80 mg po daily

Question 20

Azathioprine indications and dosing

Answer 20

1.) Renal transplantation: Adults, 3-5 mg/kg/d po immediately after the transplant, then 1-3 mg/kg po daily
2.) Rheumatoid arthritis: Adults, 1-2.5 mg/kg/d po either once daily or divided bid

Question 21

Azelastine indications and dosing

Answer 21

1.) Perennial allergic rhinitis: Adults and Children ≥12 y of age, 2 sprays per nostril bid; Children 6-12 y of age, 1 spray per nostril bid
2.) Seasonal allergic rhinitis: Adults and Children ≥12 y of age, 1-2 sprays per nostril bid; Children 6-12 y of age, 1 spray per nostril bid
3.) Vasomotor rhinitis: Adults and Children ≥12 y of age, 2 sprays per nostril bid

Question 22

Azithromycin indications and dosing

Answer 22

1.) Acute infective exacerbation of COPD, skin or tissue infection: 500mg po daily × 3 d or 500 mg po × 1 dose, then 250 mg po daily × 2-5 d
2.) Bacterial sinusitis: Adults, 500 mg po daily × 3 d; Children, 10 mg/kg po daily × 3 d, or 2 g po × 1 dose
3.) Chancroid, nongonococcal cervicitis, nongonococcal urethritis: 1 g po × 1 dose
4.) Community-acquired pneumonia: 500 mg po daily × 3 d or 500 mg po × 1 dose, then 250 mg po daily × 2-5 d; Infants ≥6 mo of age, tablets and oral suspension, 10 mg/kg po on day 1, then 5 mg/kg po daily × 2-5 d or oral suspension, <34 kg, 60 mg /kg po × 1 dose;>34 kg, 2 g po × 1 dose
5.) Sexually transmitted infections: 1-2 g po × 1 dose
6.) Streptococcal pharyngitis: 500 mg po × 1 dose, then 250 mg po daily × 2-5 d; Children, 12 mg/kg po daily × 5 d

Question 23

Baclofen Indications and Dosing

Answer 23

1.) Spasticity: 5 mg TID

Question 24

Benazepril indications and dosing

Answer 24

1.) Hypertension: 10 mg QD

Question 25

Benzonatate indications and dosing

Answer 25

1.) Cough: 100-200 mg TID PRN

Question 26

Benztropine indications and dosing

Answer 26

1.) Extrapyramidal disease, medication-induced movement disorder: Adults, 1-4 mg PO QD or BID

2.) Parkinsonism- 1-2mg/day PO

Question 27

Bimatoprost indications and dosing

Answer 27

1.) Ocular HTN and open-angle glaucoma: 1 drop in affected eyes daily in the evening.

2.) Hypotrichosis of the eyelashes: 1 drop nightly to clean, upper eyelid margin at base of eyelashes, blot excess, repeat with new sterile applicator to opposite eyelid. Do not apply to lower eyelids.

Question 28

Bisoprolol indications and dosing

Answer 28

1.) HTN: 2.5-5 mg PO QD

Question 29

Brimonidine indications and dosing

Answer 29

1.) Ocular HTN- 1 drop in affected eye Q8H

2.) Open-angle glaucoma- 1 drop in affected eyes Q8H

3.) Ocular redness (OTC indication)- 1 drop in affected eyes Q6-8H PRN

Question 30

Budesonide indications and dosing

Answer 30

1.) Asthma:
Children 1-8 with not previous inhaled corticosteroid therapy- 0.5 mg inhaled via 1-2 divided doses
Children 1-8 with previous corticosteroid therapy- 0.5 mg inhaled daily or BID, may titrate to 1 mg/day
Children>8- adults: 180-360 mcg BID via MDI, MAV 720 mcg BID

Question 31

Budesonide/Formoterol indications and dosing

Answer 31

1.) Asthma: Children>12- adults, 80 mcg/4.5 mcg 2 inhalations BID

2.) COPD: 160 mcg/4.5 mcg 2 inhalations BID

Question 32

Buprenorphine/Naloxone indications and dosing

Answer 32

1.) Opioid use disorder- 12-16 mg once daily sublingually, titrate to response.

Question 33

Bupropion indications and dosing

Answer 33

1.) Depression-
IR- 100 mg BID x 3 days, increase to 100 mg PO TID
ER (12h)- 150 mg PO QD in the morning x 3 days, increase to 150 mg PO BID
ER (24h)- 150 mg QD x 3, increase to 300 mg QD.

2.) Season affective disorder (SAD)- ER, 150 mg QD x 3, increase to 300 mg QD

3.) Smoking cessation assistance, ER: 150 mg PO QD in the morning, then 150 mg PO BID. Begin 1 week prior to smoking quit date.

Question 34

Buspirone indications and dosing

Answer 34

1.) Anxiety: 5 mg po BID-TID or 7.5mg BID

Question 35

Canagliflozin indications and dosing

Answer 35

1.) Diabetes Mellitus, type 2: 100-300 mg PO QD before first meal

Question 36

Carbamazepine indications and dosing

Answer 36

1.) Epilepsy, partial, generalized, mixed types: 200 mg PO BID, may titrate to 1200 mg PO QD.
Children <6 y, 10-20 mg/kg/day in 2-4 divided doses.
Children 6-12 y: 100 mg BID, may titrate to 800 mg QD

2.) Trigeminal neuralgia: 100 mg BID, may titrate to 1200mg daily

Question 37

Carbidopa/Levosopa indications and dosing

Answer 37

1.) Parkinsons Disease: IR- 25mg/100 mg PO TID, increase to response.
ER- 50mg/200 mg PO BID, separate by at least 12 hours.

Question 38

Carisoprodol indications and dosing

Answer 38

Disorder of musculoskeletal system: 250-350 mg PO TID and HS

Question 39

Carvedilol indications and dosing

Answer 39

1.) HFrEF: 3.125mg PO BID, titrate to 25 mg BID

2.) HTN: 6.25mg BID

3.) Impaired left ventricular function post MI: 3.125-6.25 mg PO BID

Question 40

Cefdinir indications and dosing

Answer 40

1.) Acute otitis media, pharyngitis, tonsilitis: Children 6mo-12y: 7mg/kg BID x 5-10 days or 14 mg/kg PO QD x 10 days
Adults: 300 mg BID x 5-10 days

2.) Bronchitis, acute, secondary bacterial infection: 300 mg PO BID x 5-10 days

3.) CAP, uncomplicated SSTI: 300 mg PO BID x 10 days

4.) COPD, acute exacerbation: 300 mg PO BID or 600 mg QD x 3-7 days

5.) Streptococcal pharyngitis, group A: 300 mg BID x 5-10 days or 600 mg QD x 10 days

Question 41

Cefuroxime indications and dosing

Answer 41

1.) Acute infective exacerbation of COPD, uncomplicated SSTI, acute bacterial sinusitis, uncomplicated UTI: 250-500 mg PO BID x 10 days

2.) Acute otitis media: 250 mg PO BID x 10 days

3.) Bronchitis, acute, secondary bacterial infection: 250-500 mg BID x 5-10 days

4.) Gonorrhea, uncomplicated: 1 g PO x 1 dose

5.) Pharyngitis, tonsilitis: Adults, 250 mg PO BID x 10 days

6.) UTI, acute uncomplicated cystitis, acute simple cystitis: 250 mg BID x 5-7 days

7.) Bite wound, prophylaxis or treatment: 500 mg BID in combination with an agent appropriate for anaerobes x 3-5 days for prophylaxis

Question 42

Celecoxib indications and dosing

Answer 42

1.) Osteoarthritis- 100 mg PO BID or 200 mg QD

2.) RA: 100-200 mg PO BID

3.) Ankylosing spondylitis: 100 mg BID or 200 mg QD

4.) Acute pain, primary dysmenorrhea: 200 mg PO BID prn

Question 43

Cephalexin indications and dosing

Answer 43

1.) SSTI: 500 mg BID, children- 25-50 mg/kg/day

2.) Osteomyelitis: 250 mg-1g Q6H, children 25-100 mg/kg/day divided Q6H

3.) Otitis media, RTI, UTI: 250mg-1g PO Q6H, children- 25-100 mg/kg/day PO divided Q6H

4.) Streptococcal pharyngitis: Adults, 500 mg PO Q12H x 10 days; Children- 25-50 mg/kg/day Q6H x10 days

5.) Impetigo, ecthyma: 250-500 mg PO QID x 7 days

6.) Cellulitis (nonpurulent): 50 mg PO QID x at least 5 days

Question 44

Cetirizine indications and dosing

Answer 44

1.) Perennial or seasonal allergic rhinitis: Children 6-23 mo of age, 2.5 mg po QD; 2-5 yo- 2.5-5 mg QD; children >6 years of age and Adults: 5-10 mg PO QD

2.) Urticaria, chronic: Children 6-23 mo of age, 2.5 mg PO QD; Children 2-5 yo and age: 2.5-5 mg PO QD; Childre >5 and adults, 5-10 mg PO QD

Question 45

Chlorhexidine indications and dosing

Answer 45

1.) Gingivitis- 15 mL oral rinse, swish 30 s and spit BID after tooth brushing

2.) Skin or wound cleansing: Rinse area to be cleansed, apply minimum amount of solution necessary

3.) Periodontitis: Insert 1 chip into periodontal pocket with a probing pocket depth >5mm. Up to 8 chips may be inserted in a single visit.

Question 46

Chlorthalidone indications and dosing

Answer 46

1.) HTN: 25 mg PO QD, titrate to max 100 mg QD

2.) Edema: 50 mg PO QD, titrate to max 200 mg PO QD
Systolic heart failure-associated edema, 12.5-25 mg PO QD, max 100 mg QD

Question 47

Ciprofloxacin indications and dosing

Answer 47

1.) Anthrax, postexposure prophylaxis: Adults, 500 mg BID x at least 60 days, children- 15mg/kg BID x at least 60 days

2.) Bacterial prostatitis, chronic- 500 mg PO BID x 28 days

3.) Bronchitis, lower RTI, infection of bone, SSTI, sinusitis: 500-750 mg PO BID x 7-14 days

4.) UTI:
IR- 250-500 mg BID x 3 days
ER- 500 mg Q25H x 3 days

Question 48

Ciprofloxacin otic indications and dosing

Answer 48

1.) Otitis externa, acute: 0.25 mL (single use container) into affected ears BID x 7 days

2.) Otitis media with effusion: 0.1 mL (6mg) once to each affected ear following suctioning of middle ear effusion during tube placement

Question 49

Citalopram indications and dosing

Answer 49

1.) OCD, PTSD, binge eating, premature ejaculation: 20 mg PO QD, may titrate to 40 mg QD

2.) Panic disorder: 20-30 mg QD, may titrate to 40

3.) Aggressive behavior associated with dementia: 10 mg PO QD, may increase to 20 after 3 days

Question 50

Clarithromycin indications and dosing

Answer 50

1.) Acute infective exacerbation of bronchitis: 250-500 mg PO BID x 7-14 days or ER 1000 mg QD x 7 days

2.) CAP, skin infection, sinusitis, pharyngitis: 250 mg PO BID x 7-14 days, ER tablets 1000 mg PO QD; Children >6 mo, 15 mg/kg/day divided Q12H x 10 days

3.) Disseminated infection due to M. avium-intracellulare group, prophylaxis- HIV infection, primary prevention and treatment: 500 mg BID

4.) H.pylori GI tract infection: 500 mg BID x 10-14 days in combo with other abx and PPIs

5.) Streptococcal pharyngitis (group A): 250 mg BID x 10 days

6.) COPD, acute exacerbation: 500 mg PO BID x 3-7 days

Question 51

Clindamycin oral indications and dosing

Answer 51

1.) Bacterial infectious disease, susceptible infections due to anaerobic organisms, staphylococci, streptococci, pneumococci: Adults, 150-450 mg Q6H; Children- 8-20 mg/kg/day divided Q6-8H

2.) SSTI: 150-450 mg PO Q6H; Children: 8-20mg/kg/day divided Q6-8H

3.) Infectious disease of the abdomen: Adults, 150-450 mg PO Q6H; Children 8-20 mg/kg/day divided

4.) Lower RTI: Adults, 150-450 mg PO Q6H, children: 8-20 mg/kg/day divided

5.)PID: Adults, 150-450 mg PO Q6H; Children: 8-20 mg/kg/day divided

6.) Septicemia: same as above

7.) Osteomyelitis: 600 mg PO TID x minimum of 6 weeks

8.) Diabetic foot infection: 300-450 mg PO Q6-8H

Question 51

Clindamycin oral indications and dosing

Answer 51

1.) Bacterial infectious disease, susceptible infections due to anaerobic organisms, staphylococci, streptococci, pneumococci: Adults, 150-450 mg Q6H; Children- 8-20 mg/kg/day divided Q6-8H

2.) SSTI: 150-450 mg PO Q6H; Children: 8-20mg/kg/day divided Q6-8H

3.) Infectious disease of the abdomen: Adults, 150-450 mg PO Q6H; Children 8-20 mg/kg/day divided

4.) Lower RTI: Adults, 150-450 mg PO Q6H, children: 8-20 mg/kg/day divided

5.)PID: Adults, 150-450 mg PO Q6H; Children: 8-20 mg/kg/day divided

6.) Septicemia: same as above

7.) Osteomyelitis: 600 mg PO TID x minimum of 6 weeks

8.) Diabetic foot infection: 300-450 mg PO Q6-8H

Question 52

Clindamycin topical indications and dosing

Answer 52

1.) Acne vulgaris- apply thin film BID to affected areas; Foam- once daily

2.) Bacterial vaginosis: 100 mg intravaginally hs x 3 days or 7 days

Question 53

Clobazam indications and dosing

Answer 53

1.) Lennox-Gastaut syndrome: Children >2 and <30 g: 5 mg PO QD, may titrate to 20 mg QD
Adults and children >2 yo and >30kg, 10 mg PO QD, may titrate to 40

Question 54

Clobetasol indications and dosing

Answer 54

1.) Skin disorders, corticosteroid responsive: Children >12 y and adults- apply thin layer topically to affected area BID for a max of 2 weeks

2.) Plaque psoriasis: Children >12 y and adults, apply thin layer topically to affected area BID for a max of 2-4 weeks

Question 55

Clonazepam indications and dosing

Answer 55

1.) Panic disorder: 0.25 mg PO BID, may titrate by 0.125-0.25 mg PO BID; max 1-4 mg into 2-3 doses

2.) Seizure: Infants-<10 y or <30 kg: 0.01-0.03 mg/kg/d divided 2-3 doses
Children >10 or >30kg-0.5 mg PO TID
Adults: 2-8 mg/day QD or BID

Question 56

Clonidine indications and dosing

Answer 56

1.) ADHD: Children >6- 0.1 mg ER tablet, titrate in increments of 0.1 mg/day at weekly intervals. Max= 0.4 mg/day

2.) HTN: 0.1 mg PO BID, may titrate by 0.1 mg/day at weekly intervals to 0.2-0.6 mg in 2 doses.

Question 57

Clopidogrel indications and dosing

Answer 57

1.) Acute ST segment elevation MI managed medically (without PCI) and NSTEMI: 300-600 mg PO loading dose, followed by 75 mg daily in combo with aspirin

2.) Thrombosis prevention in atherosclerotic vascular disease, following stroke, in peripheral arterial occlusive disease- 75 PO QD

Question 58

Clotrimazole/Betamethasone indications and dosing

Answer 58

1.) Tinea: Adults and Children >12 yo, apply to affected area BID, max 2 weeks or 4 weeks for tinea pedis

Question 59

Tylenol with codeine indications and dosing

Answer 59

1.) Pain: Adults, 15-60 mg PO Q4H prn, with APAP 300-1000 mg

Question 60

Colchicine indications and dosing

Answer 60

1.) Gout, acute: 1.2 mg PO at the first sign of flare followed by 0.6 mg 1 hour later, max 1.8 mg over 1 hour

2.) Gout, prophylaxis: 0.6 mg PO QD to BID, max of 1.2 mg/day or onset of diarrhea

3.) Familial Mediterranean fever: Children 4-6 yo, 0.3-1.8 mg daily, children 6-12 yo: 0.9-1.8 mg QD, Children >12 y and adults: 1.2-2.5 P OQD, increase or decrease by 0.3mg/day

Question 61

Colesevelam indications and dosing

Answer 61

1.) Primary and familial hyperlipidemia: 1.875 mg BID or 3.75 g PO QD

2.) Diabetes Mellitus, type 2: 1.875 mg PO BID or 3.75 mg PO QD

Question 62

Conjugated Estrogens indications and dosing

Answer 62

1.) Abnormal vasomotor function (menopause), atrophy of vagina or vulva, postmenopausal osteoporosis prophylaxis, female hypogonadism syndrome: 0.3 mg PO QD, continuously or cyclically

2.) Primary ovarian failure: 1.25 mg PO QD cyclically (3 weeks on, 1 week off); adjust dose to individual response

Question 63

Crisaborole indications and dosing

Answer 63

1.) Atopic dermatitis: adults and infants >3mo age, apply a thin layer to affected area BID

Question 64

Cyanocobalamin indications and dosing

Answer 64

1.) Cobalamin deficiency- 1000 mcg PO daily, Nasal- 500 mcg once weekly

2.) Cobalamin deficiency, malabsorption- 1000 mcg IM or deep SC daily for 6-7 days, then 100 mcg monthly for life

Question 65

Cyclobenzaprine indications and dosing

Answer 65

1.) Skeletal muscle spasms- 5 mg PO TID

Question 66

Cyclosporine ophthalmic indications and dosing

Answer 66

1.) Keratoconjunctivitis sicca, when associated ocular inflammation results in scanty tear production: 1 drop in affected eyes BID

Question 67

Dabigatran indications and dosing

Answer 67

1.) Treatment and prevention of initial or recurrent DVT and PE: 150 mg PO BID

2.) Prevention of stroke and systemic embolism in patients with nonvalvular Afib: 150 mg PO BID

3.) Prevention of DVT and PE after hip replacement: 110 mg PO 1-4 h postoperatively, then 220 mg PO QD x 28-35 days

Question 68

Dapagliflozin indications and dosing

Answer 68

1.) Diabetes Melitus, type 2- 5-10 mg PO QD before first meal

2.) HRrEF: 10 mg PO QD

Question 69

Darbepoetin indications and dosing

Answer 69

1.) Anemia due to chemotherapy: 2.25 mcg/kg SQ weekly, or 500 mcg SC every 3 weeks

2.) Anemia of CKD: Patients not on dialysis- 0.45 mcg/kg IV or SQ once monthly;
Dialysis- 0.45 mcg/kg IV once weekly or 0.75 mcg/kg IV or once every 2 weeks

Question 70

Darifenacin indications and dosing

Answer 70

1.) Overactive bladder- 7.5 mg PO QD

Question 71

Desvenlafaxine indications and dosing

Answer 71

1.) Depression: 50 mg PO QD

Question 72

Dexamethasone indications and dosing

Answer 72

Doses: 0.75-9 mg/day
Children- 0.02-0.3 mg/kg/day in 3-4 divided doses
1.) Allergic states (asthma)
2.) Dermatologic diseases
3.) Endocrine diseases
4.) GI diseases
5.) Hematologic disorders
6.) Neoplastic diseases
7.) Nervous system
8.) Renal diseases
9.) Respiratory diseases
10.) Rheumatic disorders

Question 73

Desvenlafaxine indications and dosing

Answer 73

1.) Erosive esophagitis, treatment: Adults and children >12- 60 mg PO QD x 8 weeks, may continue 30 mg QD x 6 months

2.) Symptomatic GERD: 30 mg PO QD x 4 weeks

Question 74

Dexmethylphenidate indications and dosing

Answer 74

1.) ADHD, methylphenidate naive patients- 2.5 mg PO BID or ER 10 mg QD (5 mg in children)

2.) ADHD, currently using methylphenidate: 1/2 of TDD of ER racemic methylphenidate.
If IR- switch to same dose

Question 75

Diazepam indications and dosing

Answer 75

1.) Alcohol withdrawal syndrome- 10 mg PO TID-QID in first 24 h, then 5 mg PO TID-QID PRN

2.) Anxiety: 2-10 mg PO BID-QID; Children- 1-2.5 mg TID-QID

2.) Seizure, adjunct: 2-10 mg BID-QID; Children- 1-2.5 mg PO TID-QID

Question 76

Diclofenac indications and dosing

Answer 76

1.) Pain- IR or capsule- 18-50 mg PO TID

2.) Dysmenorrhea- IR only, 50 mg PO TID

3.) Migraine: Powder for solution only: 50 mg PO once

4.) Osteoarthritis- 100 mg ER PO QD or BID

5.) RA- 100 mg ER PO QD or BID

6.) Ankylosing spondylitis: 25 mg (delayed release) PO QID and 25 mg PO HS PRN

Question 77

Dicyclomine indications and dosing

Answer 77

1.) IBS- Children 6 mo-2 y of age, 5 mg PO TID-QID
Children 2-12 y- 10 mg PO TID
Adults- 20 mg PO QID

Question 78

Digoxin indications and dosing

Answer 78

1.) AFib- Loading dose of 0.25 g PO Q2H to a total dose of 1.5 mg, then 0.125-0.375 mg daily

2.) Heart Failure:
Premature infant- loading dose 20 mcg/kg, then 5 mcg/kg/d
Full term infant-2 yo: loading dose 30 mcg/kg, then 8-10 mcg/kg/d
Children 2-23 mo: Loading dose of 40-50 mcg/kg, then 10-12 mcg/kg/d
2-10 yo: LD of 30-40 mcg/kg, then 8-10 mcg/kg/d
>10 yo: LD of 0.75-1.5 mg/kg, then 0.125-0.5 mg/kg PO
Adults- LD of 0.5-0.75 mg once, followed by 0.125-0.375 mg PO Q6-8H, followed by 0.125-0.5 mg PO daily

3.) Supraventricular tachyarrhythmia: LD of 0.75-1.5 mg PO TID, then 0.125-0.5 mg PO daily

Question 79

Diltiazem indications and dosing

Answer 79

1.) HTN- 60-120 mg PO BID
2.) Stable, chronic angina: 30 mg PO QID
3.) Atrial arrhythmia and paroxysmal supraventricular tachycardia- 180-360 mg PO QD

Question 80

Diphenoxylate/atropine indications and dosing

Answer 80

1.) Diarrhea- children >2y: 0.3-0.4 mg/kg/d PO in 4 divided doses (max 20 mg/day)
Adults- 2 tablets PO QID until diarrhea resolves

Question 81

Diphtheria toxoid indications and dosing

Answer 81

1.) Prevention of diphtheria
Children- as primary series of DTaP, all infants at 2,4,6 mo of age, 4th dose at 15-18 months of age, and 5th dose at 4-6 up
Booster at 11-12 years old, then Td every 10 years

Question 82

Dipyridamole indications and dosing

Answer 82

1.) Thromboprophylaxis after heart valve replacement: 75-100 mg PO QID as an adjunt to warfarin therapy

Question 83

Divalproex indications and dosing

Answer 83

1.) Absence seizure, simple and complex: 15mg/kg/d

2.) Complex partial epileptic seizure: 10-15 mg/kg/d PO

3.) Manic bipolar disorder: 25 mg/kg/d PO

4.) Migraine prophylaxis: 500 mg PO QD for 1 week, then 1 g PO QD
DR- 250 mg PO BID, increasing to 500 mg PO BID

Question 84

Donepezil indications and dosing

Answer 84

1.) Alzheimer disease, dementia (mild-moderate): 5 mg PO QD HS
2.) Alzheimer disease, dementia (moderate-severe): 5 mg PO QD QHS

Question 85

Doxazosin indications and dosing

Answer 85

1.) BPH: 1 mg PO QD; ER- 4 mg PO QD

2.) HTN: 1 mg po QD

Question 86

Doxepin indications and dosing

Answer 86

1.) Depression, anxiety, alcoholism: very mild- 25-50 mg PO QD; mild-moderate: 75 mg PO QD

2.) Insomnia: 6 mg PO QD HS, 3 mg if >65

Question 87

Doxycycline indications and dosing

Answer 87

1.) Acinetobacter infection- children <8 yo and <45 kg: 2.2-4.4 mg/kg PO in 1-2 divided doses. Children >8 and >45kg and adults: 100 mg PO BID on day one, then 100 mg QD

2.) Acne vulgaris: Children <8/<45kg- 2.2-4.4 mg/kg in 1-2 divided doses. Children >8 yo/>45 kg: 100 mg PO BID on day 1, then 100 mg PO QD or BID

3.) Gonorrhea, uncomplicated: 100 mg PO BID x 7 days or 300 mg PO single dose followed by 300 mg 1 hour later.

4.) Staphylococcal infection of skin: Children <8/<45kg: 2.2-4.4 mg/kg PO in 1-2 divided doses; Children >8/>45kg/adults- 100 mg PO BID day 1, then 100 mg PO QD

5.) CAP: 100 mg PO BID

Question 88

Dulaglutide indications and dosing

Answer 88

1.) Diabetes mellitus, type 2: 0.75-1.5 mg every week SQ

Question 89

Duloxetine indications and dosing

Answer 89

1.) Anxiety- 60 mg PO QD

2.) Depression: 20-30 mg PO BID or 60 mg once daily

3.) Diabetic peripheral neuropathy pain, fibromyalgia, musculoskeletal pain: 60 mg PO QD

May titrate to 120 mg PO QD

Question 90

Dutasteride indications and dosing

Answer 90

1,) BPH: 0.5 mg PO QD

Question 91

Edoxaban indications and dosing

Answer 91

1.) Nonvalvular AFib (prophylaxis, to prevent stroke)- 60 mg PO QD

2.) DVT/PE (treatment, following 5-10 days parenteral anticoagulant)- Adults, weight >60 kg, 60 mg PO QD, weight <60 kg, 30 mg PO QD

Question 92

Efavirenz indications and dosing

Answer 92

1.) Treatment of HIV-1 infections:
Adults and children >40 kg- 600 mg PO QD HS
Children >3m/ 3-40 kg weight based:
If coadministering with rifampin, increase efavirenz to 800 mg PO QD
If coadministering with voriconazole, decrease efavirenz to 300 mg QD and increase voriconazole to 400 mg PO BID

Question 93

Elbasvir/Grazoprevir indications and dosing

Answer 93

1.) Chronic hepatitis C (CHC) infection with genotype 1, or 4: 1 tablet PO QD, duration and addition of ribavirin vary by CHC genoyupe and NS5A genotype.

Question 94

Eletriptan indications and dosing

Answer 94

1.) Migraine: 20-40 mg PO at onset of migraine, may repeat after 2 h prn

Question 95

Emtricitabine/tenofovir disoproxil indications and dosing

Answer 95

1.) Treatment of HIV-1 infection in combo with other agents: >35kg-200/300 mg QD’ Children 17 to <35 kg- weight based

2.) Preexposure prophylaxis (PrEP) for prevention of HIV-1: infection in adults who are at high risk for acquiring HIV- 200/300 mg QD

Question 96

Enalapril indications and dosing

Answer 96

1.) HF: Infants >4 days and adolescents: 0.1-0.5 mg/kg PO QD
AdultsL 2.5 mg PO QD, titrate to 20-40 mg PO QD in divided doses.

2.) HTN: Infants >1 mo of age and adolescents, 0.08 mg/kg up to 5 mg po QD
Adults- 5 mg PO QD

3.) Kidney disease, nondiabetic: Childten 7-18 yo, 0.1-0.5 mg/kg PO QD
Adults: 5 mg PO QD

Question 97

Enoxaparin indications and dosing

Answer 97

1.) DVT prophylaxis, abdominal surgery: 40 mg SQ once 2 h prior to surgery, then daily x 7-10 days

2.) DVT prophylaxis, hip or knee replacement surgery: 30 mg SQ Q12H starting 12-24 h postoperatively x 7-14 days

3.) DVT prophylaxis, acute medical illness: 40 mg SQ daily x 6-11 days

4.) DVT Treatment: 1mg/kg SQ Q12H or 1.5 mg/kg Q24H

5.) Acute ST Segment Elevation AMI: Adults <75 yo, 30 mg IV together with 1 mg/kg SQ once, then 1 mg/kg SQ Q12H
Adults >75- 0.75 mg/kg SQ q12H

6.) Unstable angina and non-Q wave AMI: 1mg/kg SQ Q12H x 2-8 days with aspirin 100-35 mg PO QD

Question 98

Entecavir indications and dosing

Answer 98

1.) Treatment of chronic HBV infection: Adults, 0.5-1 mg PO QD, Children, weight-based dosing for patients <30Kg

Question 99

Epinephrine autoinjector indications and dosing

Answer 99

1.) Emergency treatment of acute anaphylaxis due to allergic reactions: 0.15 mg IM or SQ in children15-30 kg
>30 kg: 0.3 mg IM or SQ

Question 100

Epoetin indications and dosing

Answer 100

1.) Anemia of cancer chemotherapy: Children, 600 units/kg IV once weekly; Adults- 40.000 units SQ weekly; dose adjusted based on changes in Hgb levels

2.) Anemia of chronic renal failure: Children, 50 units/kg IV or SQ three times per week; Adults not on dialysis; 10000 units SQ weekly, 20000 units SQ every other week, 30,000 units every 3rd week, or 40,000 units SQ every 4 weeks
On dialysis- 40-100 units/kg IV or SQ 3 times per week.

3.) Anemia due to zidovudine in HIV patients: 8-17 y: 50-400 units/kg IV or SQ 2-3 times/week
Adults: 100 units/kg IV three times weekly

4.) Perioperative collection of blood for allogeneic infusion: 300 units/kg/d SQ for 10 d before surgery, on the day of surgery, and for 4 d postoperatively

Question 101

Erythromycin indications and dosing

Answer 101

1.) Bacterial infections: Adults, 250-500 mg PO BID-QID; Children: 30-50 mg/kg/d Q6-8H

Question 102

Escitalopram indications and dosing

Answer 102

1.) Depression: Children >12-adults: 10 mg QD

2.) GAD: 10 mg PO QD

Question 103

Esomeprazole indications and dosing

Answer 103

1.) H. pylori GI infection: 40 mg PO QD x 10-14 d in combo with amoxicillin 1000 mg and clarithromycin 500mg PO BID

2.) Erosive Esophagitis, GERD: Children <20kg: 10 mg QD x 8 weeks, Children >20 kg: 10-20 mg QD, Adults: 20-40 mg QD x 4-8 weeks

3.) Erosive esophagitis, heartburn: Same dosing as above.

4.) Prevention of NSAID-induced gastropathy: 20-40 mg PO QD x up to 6 months

5.) Zollinger-Ellison syndrome: 40 mg PO BID up to 240 mg/day

Question 104

Estradiol oral indications and dosing

Answer 104

1.) Abnormal vasomotor function (moderate-severe), menopause: 1-2 mg PO QD for 21 d followed by 7 days off

2.) Atrophic vulva or vagina (mod-severe), menopause: 1-2 mg PO QD in a cyclic pattern (3 week on, 1 week off)

3.) Breast cancer, metastatic: Palliation only, 10 mg PO TID x 3 mo

4.) Carcinoma of prostate, advanced, androgen-dependent, for palliation only- 1-2 mg PO TID

5.) Decreased estrogen level, secondary to hypogonadism, castration, or primary ovarian failure: 1-2 mg PO QD

6.) Postmenopausal osteoporosis, prophylaxis: 0.5 mg QD for 23 days followed by 5 d off

Question 105

Estradiol oral indications and dosing

Answer 105

1.) Abnormal vasomotor function (moderate-severe), menopause: 1-2 mg PO QD for 21 d followed by 7 days off

2.) Atrophic vulva or vagina (mod-severe), menopause: 1-2 mg PO QD in a cyclic pattern (3 week on, 1 week off)

3.) Breast cancer, metastatic: Palliation only, 10 mg PO TID x 3 mo

4.) Carcinoma of prostate, advanced, androgen-dependent, for palliation only- 1-2 mg PO TID

5.) Decreased estrogen level, secondary to hypogonadism, castration, or primary ovarian failure: 1-2 mg PO QD

6.) Postmenopausal osteoporosis, prophylaxis: 0.5 mg QD for 23 days followed by 5 d off

Question 106

Estradiol transdermal patch indications and dosing

Answer 106

1.) Abnormal vasomotor function or atrophic vagina or vulva (moderate-severe), menopause- 0.025-0.0375 mg/d patch applied to skin twice weekly.

2.) Postmenopausal osteoporosis, prophylaxis- 0.014-0.015 mg/d patch applied to skin once or twice weekly

Question 107

Eszopiclone indications and dosing

Answer 107

1.) Insomnia- 1 mg PO immediately before bedtime

Question 108

Etanercept indications and dosing

Answer 108

1.) Ankylosing sponylitis: 50 mg SQ once per week or 25 mg SQ twice weekly

2.) Polyarticular juvenile idiopathic arthritis: Children >2/<63 kf: 0.8mg/kg Sq once per week, >63kg- 50 mg once per week

3.) Plaque psoriasis- Children >4: 0.8 mg/kg/dose SQ once per week
Adults: 50 mg twice per week x 3 months, then 50 mg once per week

4.) Psoriatic arthritic: Adults, 50 mg SQ once weekly or 25 mg sc twice weekly

5.) RA: Adults, 50 mg SQ once weekly or 25 mg SQ twice weekly

Question 109

Ethinyl estradiol and etonogestrel ring indications and dosing

Answer 109

1.) Contraception: 1 ring inserted vaginally by patient and remaining continuously for 3 weeks, then remove for 1 week

Question 110

Etodolac indications and dosing

Answer 110

1.) General pain: IR- 200-400 mg PO Q6H

2.) Osteoarthritis and RA: IR- 300 mg PO BID-TID or 400-500 mg PO BID
ER- 400-1000 mg PO QD

3.) Juvenile RA: ER- 6-16 yo and 20-30 kg: 400 mg PO QD; 31-45 kg: 600 mg PO QD; 46-60kg: 800 mg PO QD; >60 kg, 1000 mg PO QD

Question 111

Exenatide indications and dosing

Answer 111

1.) Diabetes mellitus, type 2: IR- 5-10 mcg SQ BUD within 60 min prior to morning and evening meals, ER- 2 mg SQ weekly without regard to meals

Question 112

Ezetimibe indications and dosing

Answer 112

1.) Familial hypercholesterolemia-homozygous, with atorvastatin or simvastatin: Adults and children >10, 10 mg PO QD

2.) Mixed HLD: 10 mg PO QD in combo with fenofibrate

3.) Primary hypercholesterolemia: 10 mg PO QD

Question 113

Famotidine indications and dosing

Answer 113

1.) Duodenal ulcer, acute: 20 mg PO BID or 40 mg QD HS

2.) Duodenal ulcer, maintenance: 20 mg PO QD HS

3.) GERD: 20-40mg PO BID x up to 12 weeks

4.) Gastric ulcer, acute: 40 mg PO QD HS

5.) Indigestion, heartburn: 10-20 mg PO BID

Question 114

Febuxostat indications and dosing

Answer 114

1.) Hyperuricemia in patient not adequately treated with, or having adverse effects from, allopurinol: 40 mg PO QD, may titrate to 120

Question 115

Felodopine indications and dosing

Answer 115

1.) HTN- 2.5-5 mg PO QD, may increase to 10

Question 116

Fenofibrate indications and dosing

Answer 116

1.) Hypercholesterolemia, primary hypercholesterolemia, or mixed dyslipidemia: 160 mg PO QD

2.) Hypertriglyceridemia: 54-160 mg PO QD

Question 117

Fentanyl transdermal indications and dosing

Answer 117

1.) Pain, chronic: based on MME

Question 118

Fexofenadine indications and dosing

Answer 118

1.) Seasonal allergic rhinitis: 60 mg PO BID or 180 mg PO QD

2.) Idiopathic urticaria: 60 mg PO BID or 180 mg PO QD

Question 119

Fidaxomicin indications and dosing

Answer 119

1.) C.diff infection: 200 mg PO BID x 10 days

Question 120

Finasteride indications and dosing

Answer 120

1.) BPH: 5 mg PO QD
2.) Male pattern alopecia: 1 mg PO QD

Question 121

Fluconazole indications and dosing

Answer 121

1.) Candidal vulvovaginitis, uncomplicated: 150 mg PO x 1

2.) Candidal vulvovaginitis, complicated- 150 mg PO Q72H x 3 doses

3.) Candidiasis, systemic: 400 mg PO QD

4.) Cryptococcal meningitis: 400-800 mg PO QD x 8 weeks

5.) Oropharyngeal candidiasis: 100-200 mg PO QD x 7-14 days

Question 122

Fluocinonide indications and dosing

Answer 122

1.) Skin disorders, corticosteroid responsive: apply thin layer topically to affected area daily or QID

2.) Plaque psoriasis: apply thin layer topically daily-QID

3.) Atopic dermatitis: apply thin layer daily -QID

Question 123

Fluoxetine indications and dosing

Answer 123

1.) Depression: 20 mg PO QD, may titrate to 80

2.) OCD: 20 mg PO QD

3.) Panic disorder: 10 mg PO QD, may increase to 60

4.) Premenstrual dysphoric disorder: 20 mg PO QD or for 14 days prior to the start of menses

5.) Bulimia nervosa: 20 mg po QD

Question 124

Fluticasone indications and dosing

Answer 124

1.) Allergic rhinitis: 1 spray each nostril BID

2.) Nonallergic rhinitis: 2 sprays each nositril/day or 1 BID

4.) Nasal polyps: 1 spray/nostril BID

Question 125

Fluticasone oral inhaler indications and dosing

Answer 125

1.) Asthma: 88 mcg BID, titrate to max 440 mcg BID
If previously treated, start dose 88-220 mcg BID

Question 126

Fluticasone/Salmeterol indications and dosing

Answer 126

1.) Asthma: 1 disk or 2 MDI puffs Q12H, starting at dose appropriate for asthma severity

2.) COPD: 250mcg/50mcg BID

Question 127

Folic acid indications and dosing

Answer 127

Folic acid deficiency- 0.4-1 mg PO QD

Question 128

Fosinopril indications and dosing

Answer 128

1.) HF: 5-10mg QD

2.) HTN: 10 mg PO QD
May titrate to 80

Question 129

Furosemide indications and dosing

Answer 129

1.) Edema related to heart failure, renal failure: 20-80 mg PO QD

2.) HTN: 40 mg PO BID

Question 130

Gabapentin indications and dosing

Answer 130

1.) Partial seizure, adjunct: 300 mg PO TID, may titrate to 1800 mg TID

2.) Postherpetic neuralgia IR: 300 mg PO day 1, 300 mg BID day 2, 300 mg PO TID day 3, may titrate to 1800 mg/day total

Question 131

Gatifloxacin opth indications and dosing

Answer 131

1.) Bacterial conjunctivitis: 0.5% opth solution, 1 drop to affected eyes Q2 h while away day 1, then QID while awake for 6 more days

Question 132

Gemfibrozil indications and dosing

Answer 132

1.) Coronary ateriosclerosis: PPX familial combined hyperlipidemia- 600 mg PO BID

2.) Familial type V hyperlipoproteinemia- 600 mg PO BID

Question 133

Glecaprevir/Pibrentasvir

Answer 133

1.) Chronic Hepatitis C infection- 3 tabs PO QD

Question 134

Glimepiride indications and dosing

Answer 134

1.) DM, type 2: 1-2 mg PO QD

Question 135

Glipizide indications and dosing

Answer 135

1.) DM: 5-10 mg PO QD, may titrate to max 40 mg daily divided

Question 136

Guanfacine indications and dosing

Answer 136

1.) ADHD: target dose 1-7 mg/d

2.) HTN: 0.5-1 mg PO daily HS

Question 137

Haemophilus influenzae indications and dosing

Answer 137

1.) Prevention of H. influenzae type B

Question 138

Hepatitis A vaccine indications and dosing

Answer 138

1.) HepA ppx: one dose IM, then 2nd dose 6-12 months later

Question 139

Hepatitis B vaccine indications and dosing

Answer 139

1.) Prevention of HebB: 1 dose, 2nd dose 1 month later, 3rd dose 5 mo later

Question 140

HPV vaccine: indications and dosing

Answer 140

1.) Prevention of HPV: 3 dose series at 0,2,and 6 months

Question 141

Hydralazine indications and dosing

Answer 141

1.) HTN: 10 mg QID, may titrate to 25 mg QID

(max- 200 mg/day)

Question 142

Hydrochlorothiazide indications and dosing

Answer 142

1.) Edema: 25-100 mg daily

2.)HTN: 12.5-25 mg PO QD

Question 143

Hydrocodone indications and dosing

Answer 143

1.) Pain, severe: 10 mg PO Q12H

Question 144

Hydrocortisone topical indications and dosing

Answer 144

1.) Skin disorders, corticosteroid responsive: Apply thin layer topically to affected area daily to QID

Question 145

Hydroxychloroquine indications and dosing

Answer 145

1.) Lupus- 200-400 mg daily

2.) Malaria, suppression- 400 mg po Q week on same day

3.) Malaria uncomplicated- 800 mg followed by 400 mg at 6,24,48 h after initial dose

4.)RA: maintenance dose 400-600 mg PO QD

Question 146

Hydroxyzine indications and dosing

Answer 146

1.) Anxiety- 50-100 mg PO QID

2.) Pruritis: 25 mg PO TID-QID

3.) Sedation: 50-100 mg PO Q4H prn

Question 147

Ibandronate indications and dosing

Answer 147

1.) Postmenopausal osteoporosis (treatment)- 150 mg PO once monthly

2.) Postmenopausal osteoporosis (PPX): 150 mg PO once monthly

Question 148

Ibuprofen indications and dosing

Answer 148

1.) Fever: 200-400 mg PO Q4-6H PRN

2.) Pain, HA

3.) Osteoarthritis or RA: 1200-3200 mg/d

4.) Juvenile RA: 30-50mg/kg/d divided QID

Question 149

Imiquimod indications and dosing

Answer 149

1.) Actinic keratosis: 2.5% and 3.75% cream, apply once daily at bedtime for 2 weeks followed by 2 weeks no treatment

2.) Condyloma acuminatum, external: Apply topically to affected area three times per week

3.) Superficial basal cell carcinoma: apply topically daily 5 times per week

Question 150

Indomethacin indications and dosing

Answer 150

1.) Ankylosing spondylitis, osteoarthritis, RA: 25-50 mg PO BID-TID (ER-75 mg BID)

2.) Acute pain: 40 mg PO BID-TID

3.) Acute gout exacerbation: 50 mg PO TID

Question 151

Influenza virus vaccine

Answer 151

Yearly

Question 152

Insulin indications and dosing

Answer 152

1.) DM

Question 153

Ipratropium/albuterol indications and dosing

Answer 153

1.) COPD: 1 inhalation QID or 3ml nebulizer Q6H

Question 154

Irbesartan indications and dosing

Answer 154

1,) Diabetic PN: 75-300 mg QD

2.) HTN: 150-300mg QD

Question 155

Isosorbide mononitrate indications and dosing

Answer 155

1.) Angina, ppx- 30-60 mg QD, may titrate to maintenance of 120-240 mg PO QD

Question 156

Ketoconazole topical indications and dosing

Answer 156

1.) Candidiasis of skin- apply 2% cream once daily for 2 wk

2,) Dandruff: Apply 1% shampoo topically to wet hair every 3-4d for up to 8 wk

3.) Pityriasis versicolor: 2% shampoo or 2% cream

4.) Seborrheic dermatitis: Apply cream, gel, foam, to AA BID for 4 weeks

5.) Tinea corporis- 2% cream QD for 2 weeks

6.) Tinea cruris: 2% crea, QD x 2 week

7.) Tinea pedis: 2% cream topically for 6 week

Question 157

Labetolol indications and dosing

Answer 157

1.) HTN- 100 mg PO BID, maintenance 200-400 mg po BID

Question 158

Lacosamide indications and dosing

Answer 158

1.) Partial onset seizure- 100 mg PO BID: Max 200 mg PO BID

Question 159

Lamotrigine indications and dosing

Answer 159

1.) BP1D- 25 mg daily x 2 weeks, then 50 mg daily x 2 weeks, then 100 mg daily x 1 week, then 200 mg QD

2.) Partial seizure: 100-500 mg/day PO in 2 divided doses

Question 160

Lansoprazole indications and dosing

Answer 160

1.) Duodenal ulcer disease: 15 mg PO QD
2.) Gastric ulcer disease, treatment: 30 mg PO QD
3.) H.pylori GI tract infection, triple therapy: 30 mg PO BID x 10-14 days with amoxicillin 1000 mg and clarithromycin 500 mg BID
4.) Erosive esophagitis, GERD: 30 mg PO DQ
5.) Zollinger-Ellison syndrome: 60 mg PO BID

Question 161

Latanoprost indications and dosing

Answer 161

1.) Ocular HTN, open angle glaucoma- 1 drop in affected eyes daily in the evening