top 300 drugs Flashcards
Acetaminophen 300mg / Codeine 30mg
Tylenol #3
Acetaminophen 300mg / Codeine 30mg (tylenol#3) class
Analgesic/opioid
Acetaminophen 300mg / Codeine 30mg (tylenol#3) dose
1-2 tab q4-6h (max 4g APAP/day)
limit use for 5 days for acute pain
3 days for fever
Acetaminophen 300mg / Codeine 30mg (tylenol#3) contraindications
children undergoing tonsillectomy/ adenoidectomy
caution G6PD deficiency
causes hepatotoxicity
[BBW] Acetaminophen–> acute liver failure, at times resulting in liver transplant and death
Acetaminophen 300mg / Codeine 30mg (tylenol#3) dose adjustment
Hepatic (APAP)
renal (codeine)
Acetaminophen (APAP) oral
Tylenol
Acetaminophen (tylenol, Ofirmev) class
analgesic
Acetaminophen PO (tylenol) dose
650mg q 4-6h (max 4g/day APAP)
Acetaminophen (APAP) IV
Ofirmev
Acetaminophen IV (ofirmev) dose
<50 kg: 12.5 mg/kg q4h
or 15 mg/kg q6 hrs; (max single dose: 15 mg/kg/dose) ; (max daily dose: 75 mg/kg/day)
≥50 kg: 650 mg q 4h
or 1,000 mg q6 h; (max single dose: 1,000 mg/dose); (max daily dose: 4 g/day)
Acetaminophen Contraindications
caution with G6PD deficiency
causes hepatotoxicity
[BBW] Acetaminophen –> acute liver failure, at times resulting in liver transplant and death
acetaminophen dose adjustment
hepatic
Acyclovir
Zovirax
Adalimumab
Humira, Amjevita, Cyltezo
Acyclovir (zovirax) dose PO
Shingles
800mg 5 x/day for 7-10 days.
Initiate at earliest sign or symptom; most effective when initiated ≤72 hours after rash onset
Acyclovir (zovirax) dose IV
10-15 mg/kg/dose q8h for 10-14 days
Acyclovir (zovirax) contraindications
neurotoxicity esp with renal failure
Acyclovir (zovirax) dose adjustment
renal
Acyclovir (zovirax) class
antiviral
Albuterol Inhaler
Proventil, Ventolin, ProAir
Adalimumab (Humira, Amjevita, Cyltezo) ankylosing spondylitis dose
SC inj: 40mg q other wk
Adalimumab (Humira, Amjevita, Cyltezo) Crohn disease dose
initial: 160mg day 1
then after 2 wks 80 mg (day 15)
maintenance: 40 mg q week or every other
Adalimumab (Humira, Amjevita, Cyltezo) psoriatic Arthritis dose
40mg q other wk
Adalimumab (Humira, Amjevita, Cyltezo) Plaque Psoriasis dose
initial: 80mg for one dose
then after 1 wk 40mg q wk or q other wk
Adalimumab (Humira, Amjevita, Cyltezo) contraindications
[BBW] Increased risk for serious infections Discontinue for serious infection/sepsis
[BBW] Lymphoma and other malignancies in children and adolescents receiving TNF-blockers
[BBW]Active TB, including reactivation of latent TB.
Evaluate patients for TB risk factors and latent TB (with a skin test) prior to and during therapy
Alendronate
Fosamax, Binosto
Adalimumab (Humira, Amjevita, Cyltezo) class
anti rheumatic, TNF blocker
Albuterol Inhaler (Proventil, Ventolin, ProAir) dose
1-2 puffs q4-6h prn
Albuterol Inhaler (Proventil, Ventolin, ProAir) contraindications
monotherapy without concurrent use of a long-term controller meds should only be reserved for pts with mild, intermittent forms of asthma without the presence of risk factors
Allopurinol (PO)
Zyloprim
Albuterol Inhaler (Proventil, Ventolin, ProAir) class
beta 2 agonists, short acting (SABA)
Alendronate (Fosamax, Binosto) px dose
5mg qd or 35mg q wk
Alendronate (Fosamax, Binosto) tx dose
10mg qd or 70mg q wk
Alendronate (Fosamax, Binosto) contraindications
Esophageal abnormalities or high risk for adverse esophageal effects
Hypocalcemia
Inability to sit or stand upright for at least 30 minutes
Atypical femur fractures
Alendronate (Fosamax, Binosto) dose adjustment
renal
Allopurinol (IV)
Aloprim
Allopurinol PO (zyloprim) dose
100-300mg q d (800mg max/day in divided doses)
Alendronate (Fosamax, Binosto) class
Bisphosphonate
Allopurinol (Zyloprim, Aloprim) contraindication
before presc: HLA-B*58:01 allele test in pts at elevated risk for developing severe cutaneous adverse reactions (SCAR):
1-Korean patients with CKD ≥ stage 3
2- all pts of Han Chinese or Thai descent
Allopurinol (Zyloprim, Aloprim) dose adjustment
renal
Alprazolam
Xanax
Allopurinol IV (Aloprim) dose
200-400mg/m2/day in single dose
Allopurinol (Zyloprim, Aloprim) class
antigout, xanthine oxidase inhibitor
Amiodarone (PO)
Pacerone
alprazolam (Xanax) IR dose
0.25-0.5mg 3x/day (max 4mg/day)
alprazolam (Xanax) ER dose
0.5-1mg qd
titrate dose every 3 to 4 days in increments ≤1 mg/day (range: 3 to 6 mg/day)
alprazolam (Xanax) contraindication
Benzodiazepines–> anterograde amnesia
alprazolam (Xanax) dose adjustment
hepatic
Amiodarone(IV)
Nexterone
Amiodarone (PO) Pacerone dose
200-1600mg/day in 1-2 divided doses
alprazolam (Xanax) class
Benzodiazepine
Amiodarone (Pacerone, nexterone) Contraindications
Hypersensitivity to iodine
Obtain baseline and periodic liver transaminases and d/c or reduce dose if the increase > 3 times normal or doubles in a patient with an elevated baseline
initiate therapy in a clinical setting where continuous ECGs and cardiac resuscitation are available
Alternative therapies should be tried first
Prior to initiation, obtain a baseline chest X-ray and pulmonary function tests, including diffusion capacity. Repeat every 3 to 6 months.
Amiodarone (Pacerone, nexterone) dose adjustment
hepatic
Amitriptyline
Amitriptyline
Amiodarone IV (Nexterone) dose
150-300mg infused over 10min
Amiodarone (Pacerone, nexterone) Class
Class III antiarrhythmic
amitriptyline class
Antidepressant, TCA
amitriptyline dose
Depression:
25-50 mg qd at bedtime or in divided doses
can gradually increase to 100-300 mg daily
Amitriptyline contraindications
Abrupt discontinuation or interruption of antidepressant therapy has been associated with a discontinuation syndrome
Use with caution in patients with a history of cardiovascular disease; the risk of conduction abnormalities with this agent is high relative to other antidepressants
Use with caution in patients at risk of seizures, including those with a history of seizures, head trauma, brain damage, alcoholism, or concurrent therapy with medications which may lower seizure threshold
Amlodipine
norvasc
Amlodipine (Norvasc) class
antihypertensive, CCB
Amlodipine (Norvasc) dose
PO: 2.5-10mg qd
Amlodipine (Norvasc) contrainications
SEs: peripheral edema within 2-3 wks of tx
Amlodipine (Norvasc) dose adjustment
hepatic
Amoxicillin
Amoxicillin
Amoxicillin class
antibiotic, PCN
Amoxicillin dose
PO: 500mg-1g q 8-12h
Amoxicillin contraindications
avoid in pts with infectious mononucleosis –> erythematous rash during Amoxicillin tx
Amoxicillin dose adjustment
renal
Amoxicillin/ Potassium clavulanate
Augmentin
Amoxicillin/ Potassium clavulanate (Augmentin) class
antibiotic, PCN
Amoxicillin/ Potassium clavulanate (Augmentin) IR dose
PO: 500mg q 8-12h
or
875mg q 12h
Amoxicillin/ Potassium clavulanate (Augmentin) ER dose
PO:2g q 12h
Amoxicillin/ Potassium clavulanate (Augmentin) contraindications
diff content of clavulanic acid –> not all formulations are interchangeable
if use inappropriate product –> diarrhea, subtherapeutic clavulanic acid conc. –> decreased clinical efficacy
Some products contain phenylalanine
Amoxicillin/ Potassium clavulanate (Augmentin) dose adjustment
hepatic renal (avoid ER)
Ampicillin/ Sulbactam
Unasyn
Ampicillin/ Sulbactam (Unasyn) class
antibiotic, PCN
Ampicillin/ Sulbactam (Unasyn) IM+ IV dose
2:1 ratio
1-2g Ampicillin: 1.5-3g Unasyn q6h
Ampicillin/ Sulbactam (Unasyn) contraindications
hepatotoxicity
Ampicillin/ Sulbactam (Unasyn) dose adjustment
renal
Anstrazole
Arimidex
Anstrazole (Arimidex) class
Antineoplastic, aromatase inhibitor
Anstrazole (Arimidex) dose
PO: 1mg qd
Anstrazole (Arimidex) contraindications
hypercholesterolemia –> monitor LDL
decreased bone mineral density (BMD)
Apixaban
Eliquis
Apixaban (Eliquis) class
Anticoagulant, factor Xa inhibitor (oral)
Apixaban (Eliquis) dose
nonvalvular a fib: PO: 5mg BID UNLESS patient has 2 of the following: - age ≥80 years -wt ≤60 kg -Scr ≥1.5 mg/dL then reduce dose to 2.5 mg BID
Apixaban (Eliquis) contraindications
if pt with neuraxial anesthesia (epidural or spinal anesthesia) or spinal/epidural puncture