Top 200 Drugs Contraindications Flashcards by Liz Cirivello | Brainscape

Q

Contraindications of atorvastatin

A

Hypersensitivity to atorvastatin
use in breastfeeding
active liver disease
unexplained persistent elevations of serum transaminases
(drug-drug interaction CYP inhibitors/inducers)

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Q

Contraindications for dapagliflozin

A

severe renal impairment
(avoid in combination w/ DPP4s)

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Q

Contraindications for dulaglutide

A

1) Family history of medullary thyroid carcinoma
2) MEN2

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Q

Contraindications for empagliflozin

A

hypersensitivity to empagliflozin

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Q

Contraindications of ezetimibe

A

Hypersensitivity to ezetimibe
gallbladder disease
severe hepatic dysfunction
concurrent use with a statin in a pregnant or nursing mother

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Q

Contraindications of fenofibrate

A

Hypersensitivity, gallbladder disease, severe renal or hepatic dysfunction, nursing mothers

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Q

Contraindications of gemfibrozil

A

Hypersensitivity to gemfibrozil, concurrent repaglinide or simvastatin, gallbladder disease, severe renal or hepatic dysfunction
(not with statin)

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Q

Contraindications of liraglutide

A

Hypersensitivity, multiple endocrine neoplasia syndrome type 2, history or family history of medullary thyroid carcinoma

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Q

Contraindications of lovastatin

A

Hypersensitivity to lovastatin
active liver disease
use in breastfeeding
concomitant use with strong CYP3A4/5 inhibitors
unexplained persistent elevation of liver enzymes

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Q

Contraindications of glimepiride

A

Hypersensitivity to sulfonylureas, diabetic ketoacidosis

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Q

Contraindications of metformin

A

1)Hypersensitivity to metformin
2) contrast media
3) eGFR <30 mL/min/1.73 m2
4) metabolic acidosis

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Q

Contraindications for glipizide

A

1) Hypersensitivity to sulfonylureas
2) diabetic ketoacidosis
3) type 1 diabetes

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Q

Contraindications for insulin aspart

A

1) hypersensitivity
2) hypoglycemic episode

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Q

Contraindications for insulin degludec

A

1) hypersensitivity
2) hypoglycemic episode

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Q

Contraindications for insulin glargine

A

1) hypersensitivity
2) hypoglycemic episode

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Q

Contraindications of insulin human

A

1) hypersensitivity
2) hypoglycemic episode

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Q

Contraindications of insulin isophane human

A

1) hypersensitivity
2) hypoglycemic episode

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Q

Contraindications for insulin lispro

A

1) hypersensitivity
2) hypoglycemic episode

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Q

Contraindications for metformin/sitagliptin

A

Renal dysfunction
Metabolic acidosis

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Q

Contraindications for pioglitazone

A

1) Hypersensitivity to pioglitazone
2) NYHA III/IV heart failure

Q

Contraindications for pravastatin

A

1) Hypersensitivity to pravastatin
2) use in breastfeeding
3) active liver disease

Q

Contraindications for rosuvastatin

A

1) Hypersensitivity to rosuvastatin
2) active liver disease
3) use in breastfeeding

Q

Contraindications for semaglutide

A

1) hypsersensitivity
2) familial history of thyroid cancers

Q

Contraindications for simvastatin

A

1) Hypersensitivity to simvastatin
2) active liver disease
3) use in breastfeeding

Q

Contraindications for sitagliptin

A

1) hypersensitivity

Q

Contraindications for amlodipine

A

hypersensitivity to amlodipine

Q

Contraindications for amlodipine-benazepril

A

history of angioedema
anuria

Q

Contraindications for atenolol

A

hypersensitivity to atenolol
sinus bradycardia
2nd or 3rd degree AV block
overt heart failure or cardiogenic shock

Q

Contraindications for benazepril

A

hypersensitivity to benazepril
history of angioedema
anuria
concurrent use with aliskiren in patients with diabetes mellitus
concurrent sacubitril

Q

Contraindications for carvedilol

A

Hypersensitivity
bronchial asthma
severe sinus bradycardia
2nd- or 3rd-degree AV block
sick sinus syndrome
overt heart failure
cardiogenic shock
severe hepatic impairment

Q

Contraindications for chlorthalidone

A

hypersensitivity to chlorthalidone or sulfa drugs
anuria

Q

Contraindications for clonidine

A

hypersensitivity to clonidine

Q

Contraindications for furosemide

A

hypersensitivity to furosemide
anuria

Q

Contraindications for hydralazine

A

hypersensitivity to hydralazine
dissecting aortic aneurism
coronary artery disease
mitral valve rheumatic heart disease

Q

Contraindications for hydrochlorothiazide

A

hypersensitivity to hydrochlorothiazide or sulfonamide
concomitant dofetilide therapy
anuric patients

Q

Contraindications for lisinipril-HCTZ

A

sulfa drugs
anuria
history of angioedema

Q

Contraindications for losartan-HCTZ

A

sulfa drugs
anuria
aliskiren
pregnancy

Q

Contraindications for irbesartan

A

hypersensitivity to irbesartan
pregnancy
concomitant use with aliskiren

Q

Contraindications for lisinopril

A

hypersensitivity to lisinopril or other ACE inhibitors
history of ACE-induced angioedema
hereditary or idiopathic angioedema
concurrent use with aliskiren
concurrent use with sacubitril

Q

Contraindications for losartan

A

hypersensitivity to losartan or other angiotension II receptor antagonists
pregnancy

Q

Contraindications for metoprolol

A

hypersensitivity to metoprolol
severe bradycardia
2nd or 3rd degree AV block
sick sinus syndrome
decompensated heart failure
cardiogenic shock

Q

Contraindications for nifedipine

A

hypersensitivity to nifedipine
cardiogenic shock
STEMI
concurrent use of CYP3A4/5 inducers

Q

Contraindications for olmesartan

A

hypersensitivity to Olmesartan or other ARB
pregnancy
concurrent use with aliskiren in diabetes patients

Q

Contraindications for prazosin

A

hypotension

Q

Contraindications for propanolol

A

hypersensitivity to propranolol
asthma
sinus bradycardia
AV block
sick sinus syndrome
cardiogenic shock

Q

Contraindications for spironolactone

A

hypersensitivity to spironolactone
anuria
acute renal insufficiency
hyperkalemia

Q

Contraindications for triamterene-HCTZ

A

hypersensitivity to hydrochlorothiazide, sulfonamides, triamterene
concomitant use of potassium supplements, potassium containg salt substitutes, or other potassium sparing diuretics
anuria
acute/chronic renal insufficiency
hyperkalemia

Q

Contraindications for valsartan

A

hypersensitivity to valsartan
pregnancy
concurrent use with aliskiren in patient with diabetes