Top 200 Drugs Contraindications Flashcards
Contraindications of atorvastatin
Hypersensitivity to atorvastatin
use in breastfeeding
active liver disease
unexplained persistent elevations of serum transaminases
(drug-drug interaction CYP inhibitors/inducers)
Contraindications for dapagliflozin
severe renal impairment
(avoid in combination w/ DPP4s)
Contraindications for dulaglutide
1) Family history of medullary thyroid carcinoma
2) MEN2
Contraindications for empagliflozin
hypersensitivity to empagliflozin
Contraindications of ezetimibe
Hypersensitivity to ezetimibe
gallbladder disease
severe hepatic dysfunction
concurrent use with a statin in a pregnant or nursing mother
Contraindications of fenofibrate
Hypersensitivity, gallbladder disease, severe renal or hepatic dysfunction, nursing mothers
Contraindications of gemfibrozil
Hypersensitivity to gemfibrozil, concurrent repaglinide or simvastatin, gallbladder disease, severe renal or hepatic dysfunction
(not with statin)
Contraindications of liraglutide
Hypersensitivity, multiple endocrine neoplasia syndrome type 2, history or family history of medullary thyroid carcinoma
Contraindications of lovastatin
Hypersensitivity to lovastatin
active liver disease
use in breastfeeding
concomitant use with strong CYP3A4/5 inhibitors
unexplained persistent elevation of liver enzymes
Contraindications of glimepiride
Hypersensitivity to sulfonylureas, diabetic ketoacidosis
Contraindications of metformin
1)Hypersensitivity to metformin
2) contrast media
3) eGFR <30 mL/min/1.73 m2
4) metabolic acidosis
Contraindications for glipizide
1) Hypersensitivity to sulfonylureas
2) diabetic ketoacidosis
3) type 1 diabetes
Contraindications for insulin aspart
1) hypersensitivity
2) hypoglycemic episode
Contraindications for insulin degludec
1) hypersensitivity
2) hypoglycemic episode
Contraindications for insulin glargine
1) hypersensitivity
2) hypoglycemic episode
Contraindications of insulin human
1) hypersensitivity
2) hypoglycemic episode
Contraindications of insulin isophane human
1) hypersensitivity
2) hypoglycemic episode
Contraindications for insulin lispro
1) hypersensitivity
2) hypoglycemic episode
Contraindications for metformin/sitagliptin
Renal dysfunction
Metabolic acidosis
Contraindications for pioglitazone
1) Hypersensitivity to pioglitazone
2) NYHA III/IV heart failure
Contraindications for pravastatin
1) Hypersensitivity to pravastatin
2) use in breastfeeding
3) active liver disease
Contraindications for rosuvastatin
1) Hypersensitivity to rosuvastatin
2) active liver disease
3) use in breastfeeding
Contraindications for semaglutide
1) hypsersensitivity
2) familial history of thyroid cancers
Contraindications for simvastatin
1) Hypersensitivity to simvastatin
2) active liver disease
3) use in breastfeeding
Contraindications for sitagliptin
1) hypersensitivity
Contraindications for amlodipine
hypersensitivity to amlodipine
Contraindications for amlodipine-benazepril
history of angioedema
anuria
Contraindications for atenolol
hypersensitivity to atenolol
sinus bradycardia
2nd or 3rd degree AV block
overt heart failure or cardiogenic shock
Contraindications for benazepril
hypersensitivity to benazepril
history of angioedema
anuria
concurrent use with aliskiren in patients with diabetes mellitus
concurrent sacubitril
Contraindications for carvedilol
Hypersensitivity
bronchial asthma
severe sinus bradycardia
2nd- or 3rd-degree AV block
sick sinus syndrome
overt heart failure
cardiogenic shock
severe hepatic impairment
Contraindications for chlorthalidone
hypersensitivity to chlorthalidone or sulfa drugs
anuria
Contraindications for clonidine
hypersensitivity to clonidine
Contraindications for furosemide
hypersensitivity to furosemide
anuria
Contraindications for hydralazine
hypersensitivity to hydralazine
dissecting aortic aneurism
coronary artery disease
mitral valve rheumatic heart disease
Contraindications for hydrochlorothiazide
hypersensitivity to hydrochlorothiazide or sulfonamide
concomitant dofetilide therapy
anuric patients
Contraindications for lisinipril-HCTZ
sulfa drugs
anuria
history of angioedema
Contraindications for losartan-HCTZ
sulfa drugs
anuria
aliskiren
pregnancy
Contraindications for irbesartan
hypersensitivity to irbesartan
pregnancy
concomitant use with aliskiren
Contraindications for lisinopril
hypersensitivity to lisinopril or other ACE inhibitors
history of ACE-induced angioedema
hereditary or idiopathic angioedema
concurrent use with aliskiren
concurrent use with sacubitril
Contraindications for losartan
hypersensitivity to losartan or other angiotension II receptor antagonists
pregnancy
Contraindications for metoprolol
hypersensitivity to metoprolol
severe bradycardia
2nd or 3rd degree AV block
sick sinus syndrome
decompensated heart failure
cardiogenic shock
Contraindications for nifedipine
hypersensitivity to nifedipine
cardiogenic shock
STEMI
concurrent use of CYP3A4/5 inducers
Contraindications for olmesartan
hypersensitivity to Olmesartan or other ARB
pregnancy
concurrent use with aliskiren in diabetes patients
Contraindications for prazosin
hypotension
Contraindications for propanolol
hypersensitivity to propranolol
asthma
sinus bradycardia
AV block
sick sinus syndrome
cardiogenic shock
Contraindications for spironolactone
hypersensitivity to spironolactone
anuria
acute renal insufficiency
hyperkalemia
Contraindications for triamterene-HCTZ
hypersensitivity to hydrochlorothiazide, sulfonamides, triamterene
concomitant use of potassium supplements, potassium containg salt substitutes, or other potassium sparing diuretics
anuria
acute/chronic renal insufficiency
hyperkalemia
Contraindications for valsartan
hypersensitivity to valsartan
pregnancy
concurrent use with aliskiren in patient with diabetes
