top 100 warnings

Question 1

Atomoxetine

Answer 1

May increase suicidal thoughts and actions in pediatric patients.

Question 2

Rosuvastatin

Answer 2

Pregnancy X

Question 3

Clonidine

Answer 3

Epidural clonidine is NOT recommended for perioperative, obstetrical, or postpartum pain (severe pain is an off label use).
Must dilute concentrated injectible (500 mcg/ml) prior to use

Question 4

Amphetamine/Dextroamphetamine

Answer 4

Potential for drug dependance exists: avoid abrupt discontinuation in patients who have received for prolonged periods.

Question 5

Propranolol

Answer 5

Therapy should not be withdrawn abruptly but gradually tapered to avoid acute tachycardia, hypertension, and/or ischemia

Question 6

Pravastatin

Answer 6

Pregnancy X

Question 7

Lovastatin

Answer 7

Pregnancy X

Question 8

Ezetimibe/Simvastatin

Answer 8

Pregnancy X

Question 9

Warfarin

Answer 9

Pregnancy X. May cause major or fatal bleeding.

Question 10

Enoxaparin

Answer 10

Spinal or epidural hematomas may occur with neuraxial anesthesia or spinal puncture in patients anticoagulated with LMWH.

Question 11

Spironolactone

Answer 11

Shown to be tumorigenic in chronic toxicity animal studies. Avoid unnecessary use.

Question 12

Irbesartan

Answer 12

Pregnancy - drugs that act on the angiotensin system can cause fetal injury and death in 2nd and 3rd trimesters. Stop therapy as soon as pregnancy is detected.

Question 13

Olmesartan

Answer 13

Can cause fetal injury and death when used in the 2nd and 3rd trimesters. D/C use as soon as pregnancy is detected.

Question 14

Benazepril/HCTZ

Answer 14

ACEIs can cause injury and death to developing fetus when used in 2nd and 3rd trimesters. D/C use as soon as pregnancy is detected.

Question 15

Enalapril

Answer 15

Injury and death to developing fetus when used in 2nd and 3rd trimesters. D/C use once pregnancy is detected.

Question 16

Quinapril

Answer 16

Injury and death to developing fetus when used in 2nd and 3rd trimesters. D/C use once pregnancy is detected.

Question 17

Amlodipine/benazepril

Answer 17

Injury and death to developing fetus when used in 2nd and 3rd trimesters. D/C use once pregnancy is detected.

Question 18

Varenicline

Answer 18

Serious neuropsychiatric events

(depression, suicidal thoughts and suicide)

have been reported. Before prescribing the risks of serious neuropsychiatric events must be weighed

against the immediate and long term

benefits of smoking abstinence for each

patient.

Question 19

Amiodarone

Answer 19

Only for life-threatening arrhythmias due to

risk of toxicity.

Severe and fatal liver toxicity.

Pulmonary toxicity (lung damage without

symptoms.

Can exacerbate arrhythmias