Top 100 Secrets Flashcards
What are findings in myopathies?
proxmial symmetric weakness WITHOUT sensory loss
What is the triad of spinal cord disease?
distal symmetric weakness
sphincter problems
sensory level
Unilateral lesion in brainstem causes what?
causes “crossed syndrome”
ipsilateral dysfxn of CN
contralateral hemiparesis and/or hemisensory loss
what causes memory formation?
long-term potentiation
NT deficiency in alzheimers
Acetylcholine
NT deficiency in epilepsy
GABA
NT deficiency in parkinsons
dopamine
NT deficiency in migraine
serotonin
What muscle weakness causes a foot drop?
tibialis anterior muscle
what lesion causes a foot drop?
Common peroneal nerve
Or L5
Which portion of the face is paralyzed in Bells palsy? What nerve is damaged?
entire face
lower motor neuron of CN VII
what portion of the face is paralyzed with UMN of CN VII? Why?
Lower face because the upper face is innervated by bilateral CN VII
What causes a dilated or “blown” pupil?
compression of CN III by aneurysm or brain herniation
Which type of hydrocephalus is a medical emergency?
non-communicating hydrocephalus because increased ICP
How do you diagnose myopathies?
- CK
- EMG
- muscle biopsy
what is the most common muscular dystrophy in adults?
myotonic dystrophy
What structure is impaired in lamert-eaton myastenic syndrome?
pre-synaptic voltage gated calcium channels
what is myotonia?
delayed relaxation after muscle contraction
What does muscle disease show on EMG?
full contraction with short, small, motor units
what does nerve disease show on EMG?
dropout and reduction in muscle contraction
prolonged, large motor units
most common causes of peripheral neuropathy
diabetes and alcoholism
most common cause of motor neuropathy
guillan-barre
what is the most common overlooked cause of peripheral neuropathy?
genetic
spinal fluid of guillan barre?
high protein and low cell counts (normal)
most common motor neuron disease
ALS
indications for surgery in patient with radiculopathy
- intractable pain
- progressive motor weakness or sensory deficits
- symptoms refractory to reasonable degree of nonoperative therapy