Tobacco/Vaping

Question 1

What are some systems affected by cigarette smoking?

Answer 1

Skin, teeth, respiratory system, CV system, immune system, and repro system

can also lead to cancer and diabetes. yikes .

Question 2

What are some “benefits” of vaping?

Answer 2

Less expensive, taste better, no stink of cigarette smoke, looks improve (whiter teeth, better skin and hair), sense of smell/taste improve, increase social interactions, less damage to lungs, supposedly helps you stop smoking but then you’re vaping literally way more often than you smoke so idk feels kinda pointless

Question 3

What is found in an e-cig?

Answer 3

an aerosol w nicotine, flavoring, and other additives

Question 4

Is vaping addictive?

Answer 4

YES. people are dumbasses, it has nicotine in it

Question 5

Why are adolescents more vulnerable to addiction?

Answer 5

Their prefrontal cortex isn’t developed, so aren’t as skilled at differentiating btwn conflicting thoughts, recognizing good v bad outcome, anticipating consequences and outcomes, and motivation to work towards a defined goal

Question 6

How does nicotine affect the prefrontal cortex?

Answer 6

Neuroplasticity is impaired!! brain can’t change continously throughout life

leads to alterations in gene expression, cell structure, intracellular signaling, synaptic pruning, and axon myelination

Question 7

What did studies show happens long term to adolescents using nicotine?

Answer 7

impaired accuracy and impulse control - decreased prefrontal memory and attention. more susceptible to substance abuse and mental health problems

Question 8

What seems to be responsible for the recent outbreak of lung illness linked to vaping?

Answer 8

Vitamin E oil

Question 9

What is mediated by the CB1 receptor?

Answer 9

analgesia, appetite enhancement, muscle relaxation, and hormonal actions

Question 10

Which receptors does dronabinol act on?

Answer 10

CB1 and CB2 receptors - less efficacy at CB2

Question 11

What psychological effects does dronabinol elicit and how long do they last?

Answer 11

4-6 hours. Affective, sensory, somatic, and cognitive

Question 12

What are the indications for dronabinol?

Answer 12

anorexia in AIDs pt, chemo induced N/V

off label: moderate to severe obstructive sleep apnea .

Question 13

Nabilone use

Answer 13

THC capsule for chemo N/V

Question 14

What are the adverse affects of cannabinoid medications?

Answer 14

affects judgement and coordination
Sedation
Bloodshot eyes
Depression
Dizziness
Tachycardia
Hypotension
Hallucinations 
Dry mouth

Question 15

What chronic pain conditions is cannabis useful for?

Answer 15

Neuropathic pain - RA, fibromyalgia, cancer pain

Question 16

What are some benefits of cannabinoids?

Answer 16

Sleep quality, tourette’s syndrome, parkinson’s disease (unclear), and alzheimers disease (unclear)

Question 17

What are some conditions where cannabis is NOT effective?

Answer 17

Acute pain
Tremor is MS
Huntington's
Gluacoma 
Schizophrenia 
Depression 
Slowing cancer growth

Question 18

What are CIs to cannabis use?

Answer 18

history of psychosis
Current/past substance abuse disorder
CV or resp disease

Question 19

What are some situations to be cautious about?

Answer 19

Age <25
Active mood disorders
Risk factors for CV disease
Ongoing use of high doses of alcohol or benzodiazepines

Question 20

What form of cannabidiol (CBD) has the highest bioavailability?

Answer 20

aerosolized inhaled CBD

Question 21

Where does CBD metabolism take place?

Answer 21

the liver by CYP3A4 and CYP2C19 mainly

Question 22

What are some adverse CBD reactions in humans?

Answer 22

increased drowsiness, decreased appetite, anemia, infections.

Question 23

What are some things NOT seen in CBD use that are seen w use of some other drugs?

Answer 23

no psychoactive effects, no potential for abuse, no tolerance or withdrawal reported, no effect on embryonic development (little research)

Question 24

When is CBD useful?

Answer 24

Rare childhood epilepsies (Dravet and Lennox-Gastaut syndrome) in people 2 years or older! cut seizures per day in half.

Question 25

What is required for a patient to get medical marijuana?

Answer 25

recommendation from licensed doctor
qualifying condition
+/- medical card