Tobacco Flashcards
Active principle
1.Nicotine
2 Anabasine
3.Nicotianine
Classification-
Ayurveda - Sthavar Upvisha
Modern- Cardiac Poison
Mechanism of Action
Stimulate then depress and later paralyses autonomic ganglia
Fatal Dose
Nicotine 60mg
Naturally formed tobacco 15-30 gm
Fatal blood level 1mg/100ml
Fatal period
5 to 15 mins
Fatal period
5 to 15 mins
Signs and symptoms
- Mild poisoning
- Acute Poisoning
- Chronic Poisoning
Mild Poisoning
Consumption or smoking or 1st time excessive smelling taken
VERTIGO
NAUSEA
VOMITING
HEADACHES
SWEATING
WEAKNESS
Acute poisoning
Central and peripheral nervous system
1.GIT Burning sensation from mouth to stomach Salvation Nausea Vomiting Abdominal pain Anorexia Inc acidity
2.Cardio pulmonary
Tachy hypertension tachyponea (early)
Brady hypo resp depression
3.Nervous
Small dose - Constriction of pupil Confusion Headache Restlessness Pyrexia
Large dose-
Dilated pupils
Convulsions
Coma
Death due to cardiac failure
Respiratory depression
CNS weakness
Chronic poisoning
Working in tabacco factory (skin Disease conjunctivitis dyspnea)
Inhalation smoking
Tabacco smoking -
Tobacco heart irregularities angina pectoris
Tabacco amblyopia optic nerve atropy blurred vision
Loss accommodation blindness area
Occlusive thromboangitinis or burger disease excessive swelling of blood vessel
GIT - Cancer nausea anroxiea headache
CNS tremors insomnia impaired memory restlessness headache
Treatment
Mahalaxmi vilas rasa with gold and madha
Tankan lahi
Stomach wash kmno4 Emesis sodium sulphate Inj atropine 1.5mg Artificial respiration Cardiac monitor Tachycardia digitalis Convulsions- diazepam Rehabilitation
Post mortem
- sign of asphyxia
- Odour route odour in stomach brownish hypostasis in stomach
- Changes of gastric irritation and pulmonary edema
Mediolegal
- poisoning is Accidental commomly
- rarely as abortifacient
- SH and infanticide
- Secreted in milk
- malingering axilia bandage fake fever
- Drug of abuse
