TISSUES Flashcards
Four Basic Tissue Types
Epithelial
Connective
Muscular
Nervous
cells producing very abundant ECM
Connective
composed of elongated cells specialized for contraction and movement
Muscular
cells with long, fine processes specialized to receive, generate, and transmit nerve impulses
Nervous
cells responsible for the organ’s specialized functions
PARENCHYMA
cells of which have a supporting role in the organ, always made up of connective tissue (except in brain and spinal cord)
STROMA
line all external and internal surfaces of the body.
All substances that enter or leave an organ must cross this type of tissue.
composed of closely aggregated polyhedral cells adhering strongly to one another and to a thin layer of ECM
forms cellular sheets that line the cavities of organs and coyer the body surface
EPITHELIAL TISSUE
PRINCIPAL FUNCTIONS OF EPITHELIAL
Covering, lining, and protecting surfaces (eg, epidermis)
Absorption (eg, the intestinal lining)
Secretion (eg, parenchymal cells of glands)
generally have elongated nuclei,
Columnar cells
have flattened nuclei,
Squamous cells
have more spherical nuclei
cuboidal or pyramidal cells
The basal surface of all epithelia rests on a thin extracellular, felt-like sheet of macromolecules referred to as the ___
a semipermeable filter for substances reaching epithelial cells from below.
BASEMENT MEMBRANES
Nearest the epithelial cells
Thin, electron-dense, sheet-like layer of fine fibrils
BASAL LAMINA
Beneath the basal lamina
More diffuse and fibrous
RETICULAR LAMINA
self-assemble into a two- dimensional network of evenly spaced subunits resembling the mesh of a window screen,
Type IV collagen
: These are large glycoproteins that attach to transmembrane integrin proteins in the basal cell membrane and project through the mesh ,formed by the type IV collagen
Laminin
a short, rod-like protein and a proteoglycan, both of these cross-link laminins to the type IV collagen network, helping to provide the basal lamina’s three-dimensional structure. to bind the epithelium to that structure, and to determine its porosity and the size of molecules able to filter through it.
Nidogen and perlecan
contains type III collagen and is bound to the basal lamina by anchoring fibrils of type Vil collagen, both of which are produced by cells of the connective tissue
RETICULAR LAMINA
SPECIALIZATIONS OF THE APICAL CELL SURFACE
MICROVILLI
STEREOCILIA
CILIA
In epithelia specialized for absorption. L. villus, tuft), usually of uniform length.
- In cells such as those lining the small intestine, densely packed __ are visible as a brush or striated border projecting into the lumen.
microvilli
- Much less common type of apical process, best seen on the absorptive epithelial cells lining the male reproductive system.
- Increases the cells’ surface area, facilitating absorption.
- __ are typically much longer and less motile than microvilli, and may show branching distally.
Stereocilia
are long, highly motile apical structures, larger than microvilli and containing internal arrays of microtubules.
exhibit rapid beating patterns that move a current of fluid and suspended matter in one direction along the epithelium.
Cilia
most (if not all) other cell types have at least one short projection called a___, which is not motile but is enriched with receptors and signal transduction complexes for detection of light, odors, motion, and flow of liquid past the cell
primary cilium
TYPES OF EPITHELIA
Covering (or lining) epithelia
Secretory (glandular) epithelia