Tissue structure and function Flashcards

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1
Q

Explain why fast-twitch glycolytic muscle fibers fatigue more quickly than slow-twitch fibers.

A

Fast-twitch glycolytic fibers rely on anaerobic respiration, which generates lactic acid as a by-product, leading to rapid fatigue. Additionally, these fibers lack an extensive blood supply and have fewer mitochondria, limiting sustained energy production.

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2
Q

Describe the role of myoglobin in slow-twitch muscle fibers and explain how it supports endurance activities.

A

Myoglobin binds and stores oxygen in slow-twitch fibers, ensuring a steady supply of oxygen for aerobic respiration. This supports the production of ATP over long periods, making it essential for endurance activities like long-distance running.

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3
Q

Compare the adaptations of slow-twitch and fast-twitch muscle fibers for energy release. Include details of respiration type and the organelles involved.

A

Slow-twitch fibers use aerobic respiration, requiring a large number of mitochondria and an extensive capillary network to produce ATP efficiently. In contrast, fast-twitch fibers rely on anaerobic respiration, using glycogen reserves to produce energy quickly but in limited amounts.

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4
Q

An athlete is training for a 100m sprint event. Explain why fast-twitch fibers are crucial for their performance and how their properties align with this type of activity.

A

Fast-twitch fibers contract rapidly and with high force, making them ideal for short bursts of power required in a 100m sprint. Their reliance on anaerobic respiration allows for quick energy release without the need for oxygen, which suits the brief, high-intensity effort.

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5
Q

A researcher observes that a muscle sample contains a high density of capillaries and mitochondria. Deduce whether this muscle is predominantly composed of fast-twitch glycolytic or slow-twitch fibers, and justify your answer.

A

The muscle sample is likely from slow-twitch fibers due to the high density of capillaries and mitochondria. These features are necessary for aerobic respiration, which supports endurance activities.

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6
Q

Why do slow-twitch fibers appear red in color, and what is the physiological significance of this feature?

A

Slow-twitch fibers appear red due to their high myoglobin content, which binds oxygen. This oxygen storage enhances aerobic respiration, allowing for sustained energy production during prolonged activity.

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7
Q

Explain how the low myoglobin content in fast-twitch glycolytic fibers influences their ability to perform anaerobic respiration.

A

The low myoglobin content in fast-twitch fibers limits their oxygen storage, meaning they primarily rely on anaerobic respiration. This adaptation suits activities requiring quick energy bursts rather than prolonged endurance.

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8
Q

Discuss how the structure and function of blood supply in slow-twitch fibers contribute to the prevention of fatigue during endurance activities.

A

The dense capillary network in slow-twitch fibers ensures a continuous supply of oxygen and nutrients while removing waste products like carbon dioxide. This supports prolonged aerobic respiration, preventing fatigue during endurance activities.

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9
Q

In what ways do the structural and functional differences between fast-twitch glycolytic and slow-twitch fibers affect an individual’s suitability for particular sports? Provide examples to support your answer.

A

The rapid contraction speed and anaerobic energy release of fast-twitch fibers make them ideal for sports requiring short, explosive efforts like sprinting and weightlifting. Slow-twitch fibers, with their high endurance and aerobic capacity, are better suited for endurance sports such as marathon running or cycling.

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10
Q

Which type of muscle fiber has the least endurance and fatigues quickly?

A

Fast-twitch glycolytic fibers.

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11
Q

What type of respiration do fast-twitch glycolytic fibers primarily rely on?

A

Anaerobic respiration.

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12
Q

Why do slow-twitch fibers have a high number of mitochondria?

A

To produce large amounts of energy (ATP) through aerobic respiration over a long period.

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13
Q

What is the main function of myoglobin in slow-twitch fibers?

A

Myoglobin stores oxygen in the muscle, supporting aerobic respiration.

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14
Q

Which type of muscle fiber is better suited for marathon running?

A

Slow-twitch fibers.

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15
Q

What is the color of fast-twitch glycolytic fibers, and why?

A

They are white in color because they have little myoglobin.

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16
Q

Which type of muscle fiber is associated with generating power for activities like sprinting?

A

Fast-twitch glycolytic fibers.

17
Q

What kind of blood supply do slow-twitch fibers have?

A

They have a dense capillary network to supply oxygen and glucose for aerobic respiration.

18
Q

Why don’t slow-twitch fibers produce lactic acid during energy release?

A

Because they use aerobic respiration, which doesn’t produce lactic acid as a by-product.

19
Q

What is the primary difference in how energy is released between fast-twitch glycolytic and slow-twitch fibers?

A

Fast-twitch fibers release energy quickly using anaerobic respiration, while slow-twitch fibers release energy slowly through aerobic respiration.

20
Q

Sliding filament theory

A

CONTRACTION: Electrical impulse arrives at a motor end plate.
• This causes the sarcoplasmic reticulum (ER) to release of calcium ions into the sarcoplasm
• Calcium ions bind to troponin
• This causes troponin to change shape, moving tropomyosin away from the actin, exposing the
myosin head binding sites on the actin.
• Myosin heads (with ADP and Pi attached) bind to actin to form actin-myosin cross-bridges
• Binding causes the myosin head to move which makes the actin filaments slide past the stationary
myosin – this is the power stroke
• ADP and Pi are released from the myosin head during the power stroke
• ATP attaches to myosin head, causing it to detach from the actin.
• ATP is hydrolysed (by ATPase on the myosin head) into ADP and Pi, providing the energy to return
the myosin head to its original position
• Myosin can then reattach further up the actin and repeat
RELAXATION: When the stimulus stops Ca2+ ions are actively transported back into the
sarcoplasmic reticulum (ER).
• The calcium concentration will fall to the point where troponin and tropomyosin move back to cover
the binding sites.

21
Q

State what happens to the squamous epithelium in a person with emphysema

A

The squamous epithelium thickens which reduces elasticity