Tissue Healing-2nd half Flashcards
Tissue Healing of PPT
Tissue adaptation
- Bones, cartilage, ligaments, muscles and tendons all adapt their appearance and composition to match functional demands
- Demands are usually mechanical and can change with immobilization, inactivity or training
If therapists know the functional demands and the tissue’s responses then…? (Tissue adaptation)
therapists can manipulate the functional demands on structures during rehabilitation to optimize tissue structure and function
Stages of healing-general
-Injury can be mechanical or chemical
-Stages the same and they overlap
>After tissues are injured, whether by an acute injury or by repetitive stress, the body responses by removing damaged tissues and replacing them with healthy ones
Inflammation stage
repair is characterized by removing tissue debris and pathogens from the injured area. Lasts 2-3 days or longer
Proliferation phase
characterized by an influx of new cells, development of granulation tissue and revascularization. Overlaps acute inflammation, usually begins three days after injury
Remodeling stage
collagen laid down haphazardly is remodeled - replaced and removed. Persists for months
What are the 5 cardinal signs of inflammation? (ON TEST)
Redness Swelling Pain Heat Loss of Function
Swelling (inflammation)
hydrostatic and osmotic pressure changes draw more fluid out of the cells
Redness and Heat (inflammation)
increased blood flow to area – histamine and vasodilators
Pain (inflammation)
-original trauma can stimulate pain receptors in injured area – If capillaries are damaged, the blood supply to tissues distal to the injury site will be decreased = ischemia = pain
Why is it common to immobilize an injured area? (inflammation)
to allow healing and to prevent further trauma
-Can be immobilized with external support or by muscle guarding
Effects of Immobilization
- The effects of prolonged immobilization can be devastating
- The proper use of exercise during the early stages of rehabilitation can speed up healing
- Not exercising can create disability
- Reversibility of these changes appears to depend on the length of immobilization
Effects of Immobilization-
BONE
Weakened, decreased collagen and mineral content
Effects of Immobilization-
CAPSULE
Shrinking, increased resistance to movement-stiffer
Effects of Immobilization-
LIGAMENT
Decreased cross-links in collagen, decreased tensile strength
Effects of Immobilization-
SYNOVIUM
- Adhesion formation
- Fibrofatty tissue proliferation into joint space
Effects of Immobilization-
TENDON
Decreased cross links in collagen disorganization of collagen fibrils, decreased tensile strength
Effects of Immobilization-MUSCLE
Loss of sarcomeres in series, decreased contractile proteins (shorter , less force production)
Effects of Immobilization- CARTILAGE
Swelling, softer and weaker
Immobilization- time for adaptation to occur?
-Fairly rapid
-Ligaments and tendons show 50% decrease in tensile strength and stiffness after 8 weeks of immobilization
-Recovery can take 12- 18 months
>Gradual reloading is necessary to restore tendon and ligament strength
What is a ligament injury called?
Sprain
-classified according to degree of damage (grades)
What is the most common grades for sprains?
grades 1-2
only 15% of all knee ligament sprains are grade 3
Sprain- Grade 1
IMPORTANT
- Microscopic tear, no joint laxity or clinical instability
- No surgical intervention needed
Sprain- Grade 2
IMPORTANT
-Tearing of some fibers, moderate laxity (5-10 mm)
-Clinical instability noted – may or may not need surgical intervention
>Determined by functional abilities and demands