Tissue blood nematodes - filariasis

Question 1

Lymphatic filariasis organisms

Answer 1

Wucheria bancrofti
Brugia malayi
Brugia timori

Question 2

diagnostic form of filariasis

Answer 2

microfilariae in periph blood - released 6-12mth after infection from adult mating in lymphatics
(eosinophilia may also be seen)

Question 3

most common clinical manifestation of lymphatic filariasis

Answer 3

hydrocele

most pts asymptomatic

Question 4

onchocerca volvulus symptoms

Answer 4

pruritis, dermatitis (sowda - Chronic hyperreactive onchodermatitis - Yemen)
LAD
keratitis (punctate, sclerosing), blindness

Question 5

onchocerca DDx of nodules

Answer 5

subcutaneous cysticercosis
furuncular myiasis (botfly)

Question 6

form of onchocerca which causes pathology

Answer 6

microfilariae (not adult worms)

Question 7

protog bacterium coexisting with human filaria

Answer 7

Wolbachia

Question 8

treatment for Wolbachia
and
result

Answer 8

Doxycycline
leads to
infertility of helminth

Question 9

Loa loa vector

Answer 9

Red (tabanid) fly - Chrysops

Question 10

Onchocercosis vector

Answer 10

Blackfly - Simulium

Question 11

Chrysops breeding ground

Answer 11

Rainforests - in wet mud beneath high canopy