Spirochetes Flashcards

1
Q

Main clinical features of leptospirosis

A
Jaundice
Pulmonary
ARF
Haemorrhage
(myalgia, shin rash,CV, ocular, aseptic meningitis)
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2
Q

Rx severe / mild-mod

A

Severe - CTX / pen 7/7 (doxy, STM)

Mild-mod - azithro, amox

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3
Q

TB manifestations with HIV inf’n

A
CD4>300	CD4<200
PPD	          +ve 	-ve                     
LAD	     Unusual	common
Pulm	            UL	LL/ML
Cavitation	Common	Rare
Extra pulm	10-15%	50%+
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4
Q

When to start ARVs in TB/HIV coinfection

A

CD4 50 - within 2 months

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5
Q

RFs for MDR TB

A
smear / culture +ve during DOTS (>3/12)
contact with known MDR
contact with pt who died receiving DOTS
AIDS
DM
HCWs
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6
Q

Definition of XDR-TB

A
INH + RIF
	\+
Any quinolone
	\+
One injectible 2nd line drug 
(STM, kanamacin/amikacin, capreomycin)
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7
Q

Lepto diagnostic triad

A

Hx water/animal contact +
conjunct suffusion +
severe myalgia

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8
Q

Vector of Lyme disease

A

Ixodes tick

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