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Repro > Tig ol bitties (ERF) > Flashcards

Tig ol bitties (ERF) Flashcards

1
Q

Lactiferous ducts has what kind of epithelium

A

columnar epithelium

-note terminal ducts have cuboidal epithellium

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2
Q

extralobular or intralobular terminal duct. which one will become secretory if women begins to lactate

A

intralobular terminal ducts

-he also said acini have become true secretory units for lactation

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3
Q

the ducts and lobules have what on their outer layer that makes the milk come down during breast feeding

A

myoepithelium

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4
Q

tx with methyldopa therapy can cause what clinical thing with the woman

A

galactorrhea-amenorrhea

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5
Q

What hormone makes the big ducts & stroma to grow? Estrogen, Progesterone, Prolactin, Oxytocin

A

estrogen

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6
Q

What hormone makes the little ducts and acinar units grow? Estrogen, Progesterone, Prolactin, Oxytocin

A

Progesterone

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7
Q

What hormone develops the acini as secretory units? Estrogen, Progesterone, Prolactin, Oxytocin

A

Prolactin

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8
Q

what hormone makes the myoepithelium contract for lactation? Estrogen, Progesterone, Prolactin, Oxytocin

A

Oxytocin

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9
Q

In older woman’s breast. what remains and what is gone? ducts and lobules

A

Ducts remain, lobules gone

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10
Q

what tumor can cause premature breast development

A

estrogen-producing ovarian tumor

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11
Q

what bug is usually the cause for breast abscess/acute mastitis

A

staph

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12
Q

“idiopathic” fat necrosis of the breast is usually caused by what

A

trauma

-will see fat-laden macrophages

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13
Q

what can produce dilated ducts filled with a curious putty-like lipid-and-macrophage rich material

A

Duct ectasia

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14
Q

Lymphocytic mastopathy is an autoimmune dz that has the lymphocytes eating up TDLU’s. what other autoimmune dz’s runs w/ this

A

hashimoto’s and Type I diabetes

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15
Q

which gigantomastia has antinuclear antibodies? gestational or inflammatory gigantomastia

A

inflammatory gigantomastia

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16
Q

If TDLU’s are replaced w/ granulomas, what do we know for sure about our patient

A

she has been pregnant. The cause is presumably immune

17
Q

what is Mondor’s?

A

a thrombosed vein

18
Q

simple cyst of the breast. see a blue dome on biopsy. is it harmful

A

nope harmless

19
Q

what kind of adenosis do we feature glands w/ tall cells

A

blunt duct adenosis

-no extra malignant potential

20
Q

what adenosis do we see the acini proliferate but the basic architecture of the breast is intact.. You will triple the risk of eventual invasive cancer

A

sclerosing adenosis

21
Q

what does CK5/5 show

A

myoepithelium

22
Q

what common benign breast tumor do we see stroma hyperplasia

A

fibroadenoma

23
Q

“a fibroadenoma w/ a very cellular stroma”

A

phyllodes tumor

-could be a sarcoma

24
Q

bloody discharge and its benign. A galactogram is a great way to spot these tumors

A

intraductal papillomas

25
Q

what has a bad prognostic sign, which is due to impingement on lymphatic vessels

A

Peau d’orange

26
Q

what resembles blackheads on gross exam, and the necrotic cores can be squeezed out. Often the necrotic cores calcify.

A

comedocarcinoma

27
Q

Lady comes in thinking she got poison ivy of the nipple?? what cancer can it be

A

Paget’s of the breast, underlying cancer invading the epidermis on the nipple

28
Q

what cancer cells tend have clear cytoplasm

A

paget cells

29
Q

what carcinoma tends to have the lobules distended and lobular lesions tend to feature non-cohesiveness? ductal carcinoma in situ or lobular carcinoma in situ

A

LCIS

  • note LCIS is cadherin negative
  • note DCIS is cadherin positive
30
Q

what do we commonly see in invasive ductal carcinoma

A

indian files

31
Q

Big polygonal cells, lots of lymphocytes? DCIS, LCIS, meduallary carcinoma

A

medullary carcinoma

32
Q

Invasive LCIS or DCIS. which one do we see signet ring cells

A

invasive LCIS

33
Q

what does the patient have if they have active-looking ducts often w/ loose surrounding stroma, but no glands

A

gynecomastia

34
Q

what is the grading system for non-invasive breast cancer via the college of american pathologist

A

1) nuclei are uniform, not bigger than 2.o RBC diameter’s
2) In-between
3) Nuclei are generally bigger than 2.5 RBC diameters and the chromatin is coarse, nucleoli are multiple and/or prominent, just looks ugly

35
Q

Nottingham-bloom-richardson grading system for invasive breast cancer

A

Look at powerpoint

36
Q

when do we think of breast cancer in fat

A

inflammatory breast cancer

37
Q

Patients with breast cancer often present with what cheif complaint

A

BONE PAIN, deals with osteoblast

Repro (10 decks)

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