Thyroid Hormone

Question 0

What does TSH do?

Answer 0

Stimulates thyroid gland to produce T3 and T4

By stimulating follicular cells to take up colloid droplets containing thyroglubulin

Question 1

What type of hormone are thyroid hormones?

Answer 1

Amino acid derivatives

Question 2

What does the hypothalamus produce?

Answer 2

TRH (thyroid releasing hormone)

Question 3

Why does TRH do?

Answer 3

Stimulates the pituitary to release TSH

Question 4

What type of receptor is the thyroid Hormone receptor

Answer 4

Steroid receptor (nuclear hormone receptor)

Question 5

What is goitre?

Answer 5

Fat neck due to enlarged thyroid gland

Question 6

What does thyroid hormone do?

Answer 6

Raises basal metabolic rate
Increases N° adrenergic beta receptors in tissues
Responsible for maturation of bones, lungs and brain in fetus

Question 7

Symptoms of hyperthyroidism

Answer 7

Weight loss, increased appetite, tremor, heat intolerance (high metabolic rate), restlessness, goitre, tachycardia, AF and hypertension

Question 8

2 treatments for hyperthyroidism

Answer 8

Surgery to remove thyroid

Carbimazole (inhibits production of thyroid hormones)

Question 9

Symptoms of hypothyroidism

Answer 9

Tiredness, weight gain, goitre, bradycardia, decreased libido, depression

Question 10

Treatment for hypothyroidism

Answer 10

Hormone replacement therapy

Question 11

How does hypothyroidism occur?

Answer 11

Low function of thyroid due to mutant receptor, therefore hormone levels are elevated
-ve feedback
Reduction in TSH production