Thyroid gland - Sukumar Flashcards
Of all the endocrine organs, which one receives the highest blood flow?
Thyroid gland
Functional unit of the thyroid gland
Follicle: consisting of layer of cells surrounding a lumen filled with colloid
*- Parafollicular cells (C cells) are found between the follicles
What is the primary constituent of colloid?
Thyroglobulin
Parafollicular Cells (C cells)
found in between follicles (fxnal unit of thyroid) that secrete calcitonin
T3 vs T4 iodinations
Why is this imp?
T3 - triiodothyronine
3, 5, 3’
T4 -
Tetraiodothyronine
3, 5, 3’, 5’
TH synthesis involves iodination of tyr residues
TH synthesis involves ______ of tyr residues, followed by the coupling of _______ to form the ___________
iodination
iodotyrosines –>
Iodothyronines