Thyroid Disorders Flashcards
cold intolerance
HYPOthyroidsm
Bradycardia
HYPOthyroidsm
Weight gain
Hypothyroid
Dry skin, brittle nails
HYPOthyroidism
Elevated TSH, low free T4
HYPOthyroidism
What does thioureas
blocks iodine organification for hyperthyroidism
What does propranolol treat?
used for symptomatic relief until hyperthroidsm is resolved
Most common form of hyperthyroidism
Graves Disease; this is an autoimmune disorder
Who gets Graves disease
women, ages 20-40, usually with a family hx
delayed DTR’s
hypothyroidism
What is a complication of hypothyroidism?
myxedema crisis: severe hypothyroidism which can lead to impaired cognition, ranging from confusion to somnolence to coma
suppressed TSH, increased T4/T3
hyperthyroidism
menorrhagia
heavy menses–> Hypothyroidsm
What labs would you expect in severe hypothyroidism?
hypothermia, hypoventilation, hyponatremia, hypoglycemia, hypotension
What drugs can cause hypothyroidism?
lithium, radiation
Heat intolerance
hyperthyroidism
loose stools, sweating
hyperthyroidism
Tachycardia
hyperthyroidism
How do you treat hypothyroidism?
Levothyroxine (T4); titrate does up every 1-3 weeks
Once at maintenance does, continue with the same brand
This is the most common thyroid disorder in the US
Hashimoto thyroiditis
Who gets hashimoto?
usually women with a strong family hx, 20-50’s
What are some disorders that hashimoto is associated with?
Usually autoimmune disorders: pernicious anemia, Sjogre
What exam findings would you see in hashimoto?
enlarged, firm and nodular thyroid; dry mouth, dry eyes; if one lobe is enlarged think neoplasm
True or False: hashimoto usually progresses to hypothyroidism
True! You don’t need to start patient on levothyroxine until TSH levels are LOW; at first presentation, TSH may be normal but these should be consistently checked
Weight loss OR gain
Hyperthyroidism
What might you find on physical exam in Graves disease?
Goiter, ophthalmopathy, exopthalmos
In endemic goiter, what are the TSH and T4 levels?
usually euthyroid but some can vary
What is an endemic goiter?
Low-iodine diet, usually only seen outside of the US in third world countries
What happens to radioactive iodine levels in Graves disease?
Elevated (RAI), radioactive iodine uptake
What are some complications of hyperthyroidism?
Increased risk of autoimmune disease, DM, celiac, Addison, vitiligo
