Thyroid disease Flashcards
1
Q
consequence of untreated congenital hypothyroidism
A
irreversible neurological defects and poor growth.
2
Q
features of congenital hypothyroidism (15)
A
Jaundice poor feeding, somnelence, lethargy nasal obstruction-flat nasal bridge refractory anaemia cardiomegaly, bradycardia, pericardial effusion dry skin narrow palpebral fissures-swollen eyelids slow reflexes poor growth hoarse voice protruding tongue hypothermia large fontanelles constipation myxoedema-coarse features, large head, swollen eyelids, peripheral oedeam
3
Q
causes of congenital hypothyroidism (5)
A
underdeveloped thyroid=most common thyroid agenesis ectopic thyroid hormone metabolism disorders transient hypothyroidism from maternal Abs/carbimazole
4
Q
Screening for congenital hypothyroidism
A
neonatal pin prick measuring:
- T3/T4/TSH
- anti-thyroid Abs
5
Q
Rx for congenital hypothyroidism (2)
A
begin L-thyroxine at Dx
transient congenital hypothyroidism doesn’t require Rx
6
Q
Cause, associations and presentation of acquired hypothyroidism (4)
A
most common is hashimoto’s
antibodies against thyroglobulin and thyroid peroxidase
assoc. w. turner’s and down’s
presents w. delayed puberty
