Thyroid and Adrenal gland Flashcards

1
Q

Another name for hyperthyroidism

A

thyrotoxicosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

hyperthyroidism mc form

A

Graves disease(autoimmune disorder most often seen in women 20-40)-antibodies attach the thyroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Thyroid storm

A

Thyroid storm (an medical emergency) symptoms like feeling hot, sweating, heart palpitations, and weight loss.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hyperthyroidism symptoms/signs

A

symptoms: nervousness, emotional lability, sweating, HEAT intolerance, fatigue, increased appetite, diarrhea, wt loss., irregular menses, palpitations, A-fib in elderly
Signs: goiter, warm moist sking, thin hair, hair loss, fine tremor, tachycardic at rest, hyperreflexia, exophthalmos, gynecomastia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

hyperthyroid labs

A

Low TSH/TRH

High T4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Normal TSH and T4 levels

A

TSH 0.4-4.8

T4 0.8-1.7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

hyperthyroid tx

A

radioactive iodine is first line
Propylthiouricil (PTU) blocks T4 concersion to T3 (active form) 100-150 mg/day PO divided q8h
surgery (euthyroid first)
BB for thyroid store, tachy, or a-fib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Hypothyroid causes

A

hashimotos thyroiditis, thryroidectomy, radiation therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

hypothyroidism s/s

A

opposite of hyperthyroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

hypothyroid labs

A

High TSH

Low T4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

hypothyroid tx

A

Levothyroxine (Synthroid) (synthetic T4)
50-100 mcg PO qd
Elderly only 25mcg
once euthyroid maintain on same brand

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Hypoparathyroidism

A

seen after thyroidectomy
manifests as hypocalcemia
occurs w/ mg deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Chvostek sign

A

Seen in hypoparathyroidism
It is the hyperirritability of facial nerve when tapped (due to low Ca++)
“stek is like steak, shove steak in face, facial nerve”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Trousseau sign

A

seen in hypoparathyroidism
carpal spasms seen w/i two minutes of inflating BP cuff over systolic pressure
‘trousseau is like trousers, use my hands to put on trousers, causes my hands to spasm, carpal spasm”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

hypoparathyroidism labs

A
low Ca++
Low parathyroid hormone Low 
low serum mg (maybe) 
high serum phosphate 
normal alk phos
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

hypoparathyroid tx

A

oral calcium and vit d

mg

17
Q

Vitamin D helps absorb what

A

Calcium

18
Q

what does PTH (parathyroid hormone ) do

A

brings Ca++ into the blood by taking it from bone, reducing loss of ca++ in urine, and by increasing absorption of calcium from intestines

19
Q

hyperparathyroidism classic symptoms

A

“bones, stones, moans, abdominal groans”
Classic symptoms: Painful bones, renal stones, ab groans, and psychic moans
other: malaise and fatigue before classic sx

20
Q

Hyperparathyroid causes

A

parathyroid adenoma, hyperplasia, carcinoma

21
Q

hyperparathyroid labs

A

High ca++ and PTH

22
Q

hyperparathyroid tx

A

surgical

hydration, inhibit bone resorption, diuretics

23
Q

Addision disease is characterized by what

A

High ACTH and low cortisol

“A for addision, A for ACTH”

24
Q

Addison dz mc cause

A

autoimmune inflammation of the adrenal cortex

25
Q

addison dz labs

A

high ACTH and low cortisol diagnostic
others: high- ca++, K+
low- na+, glucose, urea

26
Q

Addison dz s/s

A

depression, salt cravings, gi, wt loss, orthostatic hotn, delayed DTR, hyperpigmentation, vitiligo, fatigue

27
Q

addison dz tx

A

5 S’s: Salt, sugar, steroids, search, support
search for underlying cause
“add for addision, add all the s’s”

28
Q

Cushings dz

A

High cortisol due to excess ACTH by pit

“cushings i think a lot of something”

29
Q

Cushings syndrome

A

too much corticosteroid drugs

30
Q

Cushing dz and syndrome diagnostic lab and other test

A

Excretion of free cortisol in urine of >125ug/dL in 24 hours is diagnostic
Dexamethasone suppression test: 1gm dexa at 11pm, blood draw at 8am, should have 50% reduction in plasma cortisol

31
Q

Cushings s/s

A

Buffalo hump, Moonface, obesity, purple striae on skin, think skin, skeletal growth reatrdation in children, HTN