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Endocrine Week > thyroid > Flashcards

thyroid Flashcards

1
Q

hypothyroid treatment

A

levothyroxine

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2
Q

1 pituitary hypothyroid cause

A

hypopituitarism form non functioning adenoma

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3
Q

thyroid causes of hypothyroid

A

Thyroidectomy
post radioactive iodine ablation

Autoimmune
thyroiditis- postpartum, silent, Hashimoto’s
blocking TSH receptor antibodies

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4
Q

2 congenital causes of hypothyroid

A 
Thyroid dysgenesis (85%)
Dyshormonogenesis
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5
Q

4 causes of Dyshormonogenesis

A

Thyroid peroxidase
thyroglobulin
sodium iodide symporter
pendrin (Pendred syndrome) - deafness and hypothyroidism

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6
Q

Maternal thyroid disease
Neonatal hypothyroidism/cretinism
symtoms

A
  • Coarse facial features
  • Macroglossia
  • Large fontanelles
  • Umbilical hernia
  • Mottled, cool, and dry skin
  • Developmental delay
  • Pallor
  • Myxedema
  • Goiter
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7
Q

Hyperthyroidism

Investigation

A

TSH - free T4 and total T3
TSH receptor antibodies
TPO- thyroid peroxisomal antibody
123 I uptake scan

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8
Q

Hyperthyroidism symtoms

A

Eye symptoms
Petibial myxedma
Thyroid acnopalsty

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9
Q

Treatment of hyperthyroid

A

Beta blockers
Carbimazole 40 mg daily (propylthiouracil)
OR
131I (radioactive iodine)

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10
Q

pituitary cause of hyperthyroid

A

Pituitary adenoma

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11
Q

other hormone acting as TSH causing hypothyroid

A

HCG

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12
Q

Thyroid causes of hyperthyroid

A

Autoimmune

thyroid adenoma

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13
Q

what gives a thyroid bruit

A

graves

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14
Q

how does amidoarone work

A

Amiodarone - releases iodine , good for AF

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15
Q

Jod Basedow phenomenon:

A

iodine induced hyper thyroidism

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16
Q

Wolff Chaikoff effect

A

iodine induced hypo thyroidism

17
Q

Amiodarone thyroid disease
type 1
and treatment

A

autoimmune thyrotoxicosis - unmasking a previous thyroid disease
treatment high dose carbimazole

18
Q

Amiodarone thyroid disease
type 2
and treatment

A

destructive thyroiditis

treatment glucocorticoids / steroids

19
Q

Proptosis increases risk of

A

corneal ulceration

20
Q

what kind of cancer if thyroid c cell

A

medullary cancer

21
Q

4 thyroid carcinomas

A

Papillary
Follicular
Anaplastic
Poorly Differentiated

22
Q

Meduallary thyroid cancer

A

Cancer of parafollicular (calcitonin) producing thyroid cells
Familial

23
Q

3 diseases associated with Mutations of RET protoncogene

A

Familial Medullary Thyroid Cancer
Multiple Endocrine Neoplasia type 2 and 3 (MTC, phaeochromocytoma, primary hyperparathyroidism)
Hirschprungs

Endocrine Week (3 decks)

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