Thyroid

Question 1

Is T3 or T4 active (unbound)?

Answer 1

T3

Question 2

How does the negative feedback system work in stimulating thyroid hormone production?

Answer 2

Hypothalamus makes Thyroid regulating hormone TRH

The anterior pituitary makes Thyroid stimulating hormone

Question 3

What drug may cause thyroiditis?

Answer 3

amiodarone

Question 4

What can be used to differentiate between Grave’s and thyroiditis?

Answer 4

thyroid isotope scan (low uptake of iodine suggest thyroiditis)

Question 5

What causes overactive thyroid in preg?

Answer 5

HCG, in first trimester

Question 6

Signs of hyperthyroidism?

Answer 6

gritty eyes
exopthalmos
hair loss/itchy skin
proximal myopathy
heat intolerance
AF

Question 7

Eye signs in thyroiditis?

Answer 7

lid retraction, lid lag, staring eyes

Question 8

Describe how to examine eyes in thyroid exam.

Answer 8

1. Look at a pen in neutral position, checking for lid retraction
2. check for lid lag as you move pen down
3. H shape to check eye movements
4. ask about double vision when looking up and out
5. Check for exopthalmos from above

Question 9

Is a thyroid tremor coarse or fine?

Answer 9

fine

Question 10

What antibody tests for Graves?

Answer 10

TRAb

Question 11

Treatment of hyperthyroidism?

Answer 11

Carbimazole

Question 12

Side effect of carbimazole?

Answer 12

skin rashes, agranulocytosis

Question 13

Treatment of hyperthyroid in pregnancy?

Answer 13

propothyyuracil

Question 14

2nd line for hyperthyroidism?

Answer 14

radioiodine or thyroidectomy