Thyroid Flashcards
What is the dominant hormone produced by thyroid gland
-T4 (thyroxin)
Patient comes with sweating, tremors, palpitation, increase appetite with weight loss, diarrhea
Patient also notices a condition of silky hair, and decrease blood lipid.
-hyperthyroidism
What is the hormones produces by thyroid gland and which cells produce them
-T4 (follicular)
-T3 (follicular)
-calcitonin (parafollicular)
What is A cell and C cell
-A cell: follicular
-C cell: clear cell (parafollicular)
Patient comes with bradycardia, cold intolerance, coarse hair, constipation, depression, myxedema, lethargy and loss 1/3 of eyebrow.
What is the probably diagnosis
hypothyroidism
What is the tx of hyperthroidism
-PTU
-methimazole
-propanolol
-I131
-surgery
What is the tx of hypothyroidism
-levothyroxine
-liothyronin
What is the major characteristic of graves disease
-exophthalmus
-pretibial myxdema
-goiter
What is the major enzyme in thyroid synthesis
-peroxidase enzyme
(It allows oxidation, organification and coupling)
Effects of thyroid on BMR
-increase
-thus increase temperature and O2 consumption
Effects of thyroid on protein
-catabolism
-gluconeogenesis
Effects of thyroid on glycogen
-glycolysis
Effects of thyroid on vessel
-Vd
Patient comes with agitation, delirium, high fever, coma and tachycardia after the history of CT contrast
What is the probable diagnosis
-thyroid storm
Notes: it precipitates stress, trauma, job basedow phenomena
What is the normal value of free T4
-1.6
