Thyroid Flashcards
thickened skin, hair loss, constipation, lethargy, anorexia, intolerance to cold are symptoms of…
Hypothyroidism
abnormality in the thyroid gland itself
Primary hypothyroidism
pituitary gland is dysfunctional and does not secrete TSH
secondary hypothyroidism
hypothalamus gland doesn’t secrete thyrotropin-release hormone, in turn reducing TSH and thyroid hormone levels
tertiary hypothyroidism
hyposecretion during youth - low metabolic rate, retarded growth and sexual development, possibly slowed mental abilities
a. Cretinism
b. Myxedema
c. Goiter
a
enlargement of the thyroid gland – d/t overstimulation by elevated levels of TSH (b/c of lack of thyroid hormone in negative feedback loop)
a. Cretinism
b. Myxedema
c. Goiter
c. Goiter
hyposecretion during adulthood - decreased metabolic rate, loss of mental and physical stamina, weight gain, loss of hair, firm edema, yellow dullness of the skin
a. Cretinism
b. Myxedema
c. Goiter
b
synthetic T4
Levothyroxine
synthetic T3
Liothyronine
Side Effects for levothyroxine
o *Cardiac dysrhythmia o Tachycardia, palpitations, angina, hypertension o Insomnia, tremors, headache, anxiety o Nausea, diarrhea, weight loss o Menstrual irregularities o Sweating, heat intolerance
increased appetite, decreased weight, irritability, nervousness, fatigue, sleep disturbances, flushing, heat intolerance, palpitations, diarrhea, altered menstrual flow, heat intolerance are symptoms of….
Hyperthyroidism (Grave’s disease)
destroys the thyroid gland
Radioactive iodine
thioamide derivatives (methimazole* or propylthiouracil-PUT)
Antithyroid drugs
o Used to palliate hyperthyroidism; and to prevent the surge in thyroid hormones that occurs after the surgical treatment or during radioactive iodine treatment for hyperthyroidism
o May cause liver and bone marrow toxicity
Antithyroid Agents
