Adrenal Gland Flashcards
over secretion Adrenocortical Hormone
Cushing’s syndrome
Cushing’s syndrome symptoms
· High cortisol in the blood · Weight gain · Moon face · Sweating · Thinning of skin · Buffalo hump · Hirsutism
Addison’s disease
Undersecretion Adrenocortical Hormone
Symptoms of Addison’s disease
· Weight loss
· Muscle weakness, fatigue
· Low blood pressure
· Darkening of the skin
topical, systemic, inhaled, nasal
Mechanism of Action: inhibit or help control inflammatory or immune responses
Glucocorticoids
Dexamethasone (synthetic) , Hydrocortisone (natural), Prednisone (synthetic) are example of what?
Glucocorticoids
Fludrocortisone acetate* (synthetic) is a type of
Mineralocorticoids
Ketoconazole (Tx of Cushing’s syndrome) is a type of
Adrenal steroid inhibitors
true or false: Systemic forms may be given by oral, IM, IV, or rectal routes and NOT Subcutaneous
true
true or false: Oral forms should NOT be with food or milk to minimize GI upset
false
true or false: Sudden discontinuation of these agents can precipitate an adrenal crisis caused by a sudden drop in serum levels of cortisone
true