Thymoma/thymic carcinoma Flashcards

1
Q

masaoka staging of thymoma: TNM not preferred: Stage II

A

IIA: microscopic transcapsular invasion
IIB: macroscopic invasion into surrounding fatty tissue or grossly adherent to but not through mediastinal pleura or pericardium

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2
Q

stage III masaoka

A

macroscopic invsion into neighbouring organs (pericardium, great vessels, lung)
A: without great vessel invasion
B: with invasion of great vessels

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3
Q

Stage IV: masaoka

A

A: pleural or pericardial dissemination
B: lymphogenous or hematogenous metastasis.

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4
Q

in few cancers staging system other than TNM is preferred

A

thymus
testicular

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5
Q

Paraneoplastic syndrome associated with thymoma

A

myasthenia gravis
pure red cell aplasia
rheumatoid arthritis
scleroderma
addison disease
myocarditis

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6
Q

hypertension may be caused by which of the mediastinal tumor

A

phemochromocytoma
chemodectoma
neuroblastoma
ganglioneuroma

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7
Q

Differential diagnosis of anterior mediastinal mass

A

thymic tumors
thymomas
thymic carcinomas
thymic cysts
carcinoids
lymphomas
germ cell tumors: seminoma, non seminoma, CCA
parathyroid adenoma
lipoma .
liposarcomas

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8
Q

D/D of middle mediastinal tumor

A

lymphomas
cysts
pericardial mass
thoracic duct
carcinoma
cardiac and pericardial tumor
lymphadenopathy
inflammatory

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9
Q

posterior mediastinal mass

A

lymphomas
neurogenic tumor
peripheral nerve
schwannomas
neurosarcomas
neuroblastomas
paraganglia
mesenchymal tumors
endocrine tumor
esophageal tumor and cyst

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10
Q

Radiation dose for thymic carcinoma/thymoma: unresectable disaese

A

60-70 gy

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11
Q

radiation dose for thymoma: adjuvant

A

45-50 gy for clear/close margin
54 gy for microscopically positive margin
60-70gy for gross residual disease

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