Thrush - cytokines Flashcards

1
Q

Th1 cytokines: pro-inflammatory, CMI

A

IL-2
IFNg
TNFa
TNFb/LT

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2
Q

IL-12

A

produced by APCs to promote Th1 cells

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3
Q

Th2 cytokines: humoral

A

IL-4
IL-5
IL-6
IL-10

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4
Q

IL-2

A

Th1-type

potent stimulator of T cells

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5
Q

IFNg

A

Th1 type

activates macrophages, inhibits Th2 cells

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6
Q

TNFa

A

Th1 type

immune system regulator

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7
Q

TNFb/LT

A

Th1 type

stimulate neutrophils

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8
Q

IL-4

A
Th2 type
stimulates B cell proliferation, inhibits Th1 cells, regulates class switching (increases IgE)
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9
Q

IL-5

A

Th2 type

activates eosinophils

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10
Q

IL-6

A

Th2 type

stimulated B cell maturation, IgG production, role in inflammation

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11
Q

IL-10

A

Th2 type

inhibits Th1 response (anti-inflammatory)

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