thrombophilias

Question 1

potential mechanisms of thrombophilia

Answer 1

increased coagulation activity
decreased fibrinolytic activity
decreased anticoagulant activity

Question 2

hereditary thrombophilias

Answer 2

factor V leiden
prothrombin 20210 mutation
antithrombin deficiency
protein C deficiency
protein S deficiency

Question 3

management of hereditary thrombophilias

Answer 3

advice on avoiding risk factors
short term prophylaxis: during periods of known risk
short term anticoagulation- to treat thrombotic events
long term anticoagulation- if recurrent thrombotic events