Thrombophilia Flashcards
1
Q
What does thrombophilia mean?
A
increased risk of thrombosis, usually venous
2
Q
what are four inherited conditions that can cause thrombophilia?
A
factor V leiden
prothrombin gene mutation
protein C and S deficiency
antithrombin III deficiency
3
Q
what are some signs that someone might be thrombophilic?
A
arterial and venous thrombus
familial VTE
recurrent fetal loss
4
Q
what investigations should be done for thrombophilia?
A
FBC, clotting screen, fibrinogen
factor V leiden
lupus anticoagulant, anti cardiolipin abs
assays for AT, protein C and S deficiencies
PCR for prothrombin gene mutation
