Bleeding Diatheses Flashcards
1
Q
what conditions is APTT increased?
A
lupus anti coagulant haemophilia vWD DIC hepatic failure
2
Q
what conditions will PT increased ?
A
warfarin
Vit K deficiency
hepatic failure
DIC
3
Q
when will bleeding time be increased? (low platelets)
A
vWD
aspirin
DIC
BMF
4
Q
how does Ehlers danlos syndrome affect the blood?
A
connective tissue disorder which thins the skin and its easier to bruise
5
Q
what antibody is present in ITP ?
A
anti-platelet Abs
6
Q
what is bernard soulier ?
A
hereditary platelet disorder caused by GpIb deficiency
7
Q
what is glanzmanns ?
A
hereditary platelet disorder caused by GpIIb/IIIa deficiency
8
Q
what is the presentation of anti phospholipid syndrome?
A
coagulation defect (increased APTT) Livido reticularis obstetrics complications (recurrent 1st semester abortions) thrombocytopenia
