Thrombolytics Flashcards
Physiologic Plasminogen Activators
- t-PA I - Single chain plasminogen activator
- t-PA II - two chain
- Pro Urokinase
- Urokiase
Physiologic Plasminogen Inhibitors
- PAI-1 (Rapid acting plasminogen activator inhibitor)
- * Alpha2-Antiplasmin*
- C1-Esterase Inhibitor
Streptokinase Mech of Action
Fibrinolytic
Streptokinase Route of Administration
IV
Streptokinase Indications
Thrombolysis
stroke
MI
PE
Streptokinase Side Effects
bleeding
Urokinase Mech of Action
Fibrinolytic
Urokinase Route of Administration
IV
Urokinase Indications
Thrombolysis
stroke
MI
PE
Urokinase Side Effects
bleeding
Tissue Plasminogen Activator Mech of Action
Fibrinolytic
Tissue Plasminogen Activator Route of Administration
IV
Tissue Plasminogen Activator Indications
Thrombolysis
stroke
MI
Tissue Plasminogen Activator Side Effects
Bleeding
Epsilon Amino Caproic Acid (AMICAR) Mech of Action
Anti-Fibrinolytic
Epsilon Amino Caproic Acid (AMICAR) Route of Administration
IV
Epsilon Amino Caproic Acid (AMICAR) Indications
reversal of bleeding
Epsilon Amino Caproic Acid (AMICAR) Side Effects
hypotension
Aprotonin (Trasylol) Mech of Action
Anti-fibrinolytic
Aprotonin (Trasylol) Route of Administration
IV
Aprotonin (Trasylol) Indications
reversal of bleeding
Aprotonin (Trasylol) Side Effects
graft thrombosis
Ancrod Mech of Action
Fibrinolytic
Ancrod Route of Administration
IV
