Thrombolytics Flashcards

1
Q

Physiologic Plasminogen Activators

A
  • t-PA I - Single chain plasminogen activator
  • t-PA II - two chain
  • Pro Urokinase
  • Urokiase
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Physiologic Plasminogen Inhibitors

A
  • PAI-1 (Rapid acting plasminogen activator inhibitor)
  • * Alpha2-Antiplasmin*
  • C1-Esterase Inhibitor
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Streptokinase Mech of Action

A

Fibrinolytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Streptokinase Route of Administration

A

IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Streptokinase Indications

A

Thrombolysis
stroke
MI
PE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Streptokinase Side Effects

A

bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Urokinase Mech of Action

A

Fibrinolytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Urokinase Route of Administration

A

IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Urokinase Indications

A

Thrombolysis
stroke
MI
PE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Urokinase Side Effects

A

bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Tissue Plasminogen Activator Mech of Action

A

Fibrinolytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Tissue Plasminogen Activator Route of Administration

A

IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Tissue Plasminogen Activator Indications

A

Thrombolysis
stroke
MI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Tissue Plasminogen Activator Side Effects

A

Bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Epsilon Amino Caproic Acid (AMICAR) Mech of Action

A

Anti-Fibrinolytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Epsilon Amino Caproic Acid (AMICAR) Route of Administration

A

IV

17
Q

Epsilon Amino Caproic Acid (AMICAR) Indications

A

reversal of bleeding

18
Q

Epsilon Amino Caproic Acid (AMICAR) Side Effects

A

hypotension

19
Q

Aprotonin (Trasylol) Mech of Action

A

Anti-fibrinolytic

20
Q

Aprotonin (Trasylol) Route of Administration

A

IV

21
Q

Aprotonin (Trasylol) Indications

A

reversal of bleeding

22
Q

Aprotonin (Trasylol) Side Effects

A

graft thrombosis

23
Q

Ancrod Mech of Action

A

Fibrinolytic

24
Q

Ancrod Route of Administration

A

IV

25
Q

Ancrod Indications

A

Stroke

26
Q

Ancrod Side Effects

A

Allergic Reaction

27
Q

Tranexamic Acid (AMCHA) Mech of Action

A

Anti-Fibrinolytic

28
Q

Tranexamic Acid (AMCHA) Route of Administration

A

IV

29
Q

Tranexamic Acid (AMCHA) Indications

A

reversal of bleeding

30
Q

Tranexamic Acid (AMCHA) Side Effects

A

retinopathy