Thrombocytopenia in pregnancy

Question 1

The normal serum level of platelets in pregnancy is

Answer 1

150-400 *10`9/L

Question 2

mild thrombocytopenia level

Answer 2

> 100*10`9/L

Question 3

moderate thrombocytopenia level

Answer 3

50-100*10`9/L

Question 4

severe thrombocytopenia level

Answer 4

<50*10`9/L

Question 5

Causes of low platelet count

Answer 5

• Increase destruction or consumption
• dilution effect
• lack of production of platelets

Question 6

Common signs of thrombocytopenia include

Answer 6

petechiae,
nose bleeding
more rarely, haematuria and gastrointestinal bleeding.

Question 7

platelets count at late pregenancy

Answer 7

lower 10% than pre pregnancy levels

d.t. combination of dilutional effects and acceleration of platelet destruction across the placenta

Question 8

Thrombocytopenia prevalenve

Answer 8

8-10% of pregnancies

75% of them d.t. benign process of gestational thrombocytopenia

Question 9

What to do with platelets counts > 100*10`9/L and are stable

Answer 9

do not require further investigation but should be monitored.

Question 10

platelet count in gestational thrombocytopenia

Answer 10

typically >70
usually >100

no bleeding risk for mother or fetus